What is Astragalus?what is function of Astragalus?

Constituents and Phytochemicals of Astragalus Root.

Astragalus Root Extract.ASTRAGALUS MEMBRANACEUS EXTRACT.CAS 94166-93-5 EINECS No 303-391-9 Astragalus Root Extracts.Astragalosides.CAS NO 85085-21-8 Tragacanth Astragalus Gummifer Extract,Astragalus Polysaccharides.Astragalus mongholicus photo picture image Phytochemicals of Astragalus Root:ASTRAGALOSIDE-I,Astragaloside-II,Astragaloside-III,Astragaloside-IV,Astragaloside-V,Astragaloside-VI,Astragaloside-VII,Astraisoflavan,Astraperocarpan,Betaine,Calycosin,Formononetin,Gaba,Isoastragaloside-I,Isoastragaloside-II,Isoastragaloside-IV,Isoliquiritigenin,Ononin,Soyasaponin-I.
Active ingredients:total Astragloside, triterpene glycosides, polysaccharides. Astragalus contains numerous components, including flavonoids, polysaccharides, triterpene glycosides (e.g., astragalosides I-VII), amino acids, and trace minerals. Astragalus appears to restore T-cell (a specific type of white blood cell ) counts to relatively normal ranges in some cancer patients.
Astragalus contains several characteristic triterpenoid saponins known as Astragalosides which can be used for the identification and standardization of the plant . The principle compound, astragaloside IV is typically found at 0.15 mg/g. In addition it contains at least 6 isoflavonoids (total 0.02% w/w) including the estrogenic flavonoid fromononetin. Cell wall derived polysaccharides have been isolated from A. membranaceus var mongholicus and designated as astragalans I-III.
Key Components:asparagine,calcyosin,formononetin,astragalosides,kumatakenin,sterols.
Several chemical constituents of astragalus have been identified as potential active compounds, including saponins, flavonoids, polysaccharides and glycosides. Astragalus is often combined with other adaptogenic herbs, such as ginseng, and promoted as a guard against various internal and external stressors. Combination of astragalus with echinacea is common for protection against common infections of the mucous membranes (cold and flu).
Other Content:soyasapogenoside; formononentin; calycosin; canavanine;gama-aminobutyric acid; asparamide; prolin;trace minerals such as iron,zinc,etc;dimethyl 4,4-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2-dicar-oxylate; daucosterol; kaempferol; quercetin; quercetin-3-glucoside; isorhamnetin; formononetin4-O-glucoside; aspartic acid; threonine; serine; glutamic acid;glycine; alanine; methionine; isoleucine; leucinine; trytophan; phenylalanine; cystine; Beta-sitosterol; linoleic acid; linolenic acid; astrafalussaponin I,II,III; astragaloside V-VIII; kumatakenin; 1-3-hydroxy-9-methoxpterocarpan; choline; betaine; follic acid; astragaloside I,astragaloside II, astragaloside IV; 3S-(-)mucronulatol-7-D-glucopyranoside; astraglan I, astraglan II, astraglan III; etc.
New identified:some new chemicals got identified from astragalus root,such as astraisoflavanin (3S-(-)-mucronulatol-7-O-D-glucopyranoside) from alcoholic extract21..
Scientific Support:Most of the scientific data on astragalus comes from Chinese clinical evidence, where astragalus appears to stimulate the immune system in patients with infections. At least one clinical trial in the U.S. has shown astragalus to boost T-cell levels close to normal in some cancer patients, suggesting the possibility of a synergistic effect of astragalus with chemotherapy. In animal studies, astragalus extracts have been shown effective in preventing infection of mice by influenza virus, possibly by increasing the phagocytotic activity of the white blood cells of the immune system.Agroastragaloside II, a new astragaloside was isolated from the hairy root culture of Astragalus membranaceus,its structure got identified(55.).
Some recent analytic study identified that hairy roots of Astragalus membranaceus contains good source of crude saponin and astragaloside i.v,polysaccharide and isoflavonoid compounds,suggest hairy roots may be a new source of A. membranaceus(69.). Some test identified Eight flavonoids from astragalus root recently,they are calycosin-7-O-beta-D-glucoside, calycosin-7-O-beta-D-glucoside-6"-O-malonate (2), ononin, (6aR,11aR)-3-hydroxy-9,10-dimethoxypterocarpan-3-O-bet a-D-glucoside, calycosin, (3R)-7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-beta-D-glucoside, formononetin-7-O-beta-D-glucoside-6"-O-malonate and formononetin by direct comparison with the isolated standards from Astragalus Root(73.).
Studies on pharmacological junctions proved that similar to the natural A. membranaceus, hairy root of Astragalus membranaceus has senility-preventing, antioxidizing and immunomodulating functions(82.).

Reference:

1.What is Astragalus?what is function of Astragalus?

last edit date:25th,Feb.2010.

Available Product

Name:Astragalus Root Extract
Serie No:S-002.
Specifications:Polysaccharides 20%,50%UV Astragalosides 0.3%HPLC.
INCI Name:ASTRAGALUS MEMBRANACEUS EXTRACT
EINECS/ELINCS No.:303-391-9
CAS: Ligustilide.94166-93-5
Chem/IUPAC Name:Astragalus Membranaceus Extract is an extract of the roots of Astragalus membranaceus, Leguminosae

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