What is Trifolium pratense,Red Clover?History,Phytochemicals and Remedy Uses of Red Clover Blossoms.Red Clover Extract.

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Drug Interactions Summary for Red Clover,Case Stury.

Red Clover Extract Trifolium pratense CAS.NO 85085-25-2 EINECS ELINCS No.:285-356-7 INCI Name Trifolium Pratense Extract photo picture image Here is a list of medications that may interact with red clover. It is recommended you discuss the use of red clover and your current medication(s) with your doctor or pharmacist.

 Oestrogens (Reduced drug absorption/bioavailability *),Heparin (Adverse interaction *),Ticlopidine (Adverse interaction *),Warfarin (Adverse interaction *),
 Case Study:Long-term pharmacokinetics of an extract of isoflavones from red clover(Trifolium pratense).
 Objectives: To study the pharmacokinetics of isoflavones from red clover(Trifolium pratense) after long-term administration as a once-daily dietarysupplementary.

 Design: Fourteen (14) subjects who had been consuming alow-isoflavone diet for 2 weeks were given an oral dose of two isoflavonetablets (approximately 80 mg of total isoflavones) daily for 2 weeks andappeared for a study day at 9:00 AM after an overnight fast on the day that theywere to receive the last dose. Plasma samples were collected for a 48-hourperiod after the last dose. Plasma isoflavones were assayed by high-performanceliquid chromatography (HPLC). RESULTS: Trough plasma levels were significantlyhigher for daidzein and genistein after long-term dosing than levels taken priorto the commencement of the study and plasma levels of isoflavones afterlong-term dosing were in the range previously reported in populations thatconsume an isoflavone-rich diet. The plasma half-lives observed after long-termadministration were, in most cases, consistent with once-daily administration.

 Conclusions: Isoflavones have pharmacokinetic characteristics that suggest thatonce-daily administration is adequate when they are administered long-term asdietary supplements.

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citations1.What is Trifolium pratense,Red Clover?History,Phytochemicals and Remedy Uses of Red Clover Blossoms.Red Clover Extract.

last edit date:5th,May.2009.