What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?
Article Content:
- .Standard Description of Common cnidium fruit extract.
- .Basic Botanical Data of Cnidium plant and Cnidium Seeds.
- .Pharmacology Actions of of Osthol.
- .Cnidium Monnier works for Eva and Adam.
- .Application and Indications of Osthole.
- .HPLC Determination of Osthole in Rat Plasma after Oral Administration of Fructus Cnidii Extract.
- .Why must throw away Viagra and other out dated thing and choose Natural Cnidium Fruit?
- .Safety and Acute toxicity
- .Cnidium Monnier Research Update.
Standard Description of Common cnidium fruit extract.
Product Name: Fructus Cnidii Powder Extracts:Osthole(C15H16O3)10%HPLC
Standard Name: Standard Common cnidium fruit extract(Fructus Cnidii Extract Standardized to Osthol(C15H16O3)10%HPLC)
Common name: Common Cnidium Fruit Extract
Extracts Synoms:Common Cnidium Fruit P.E. Cnidium Seeds Extracts;Semen Cnidii extracts;Cnidium bhutanicum extracts
Botanical Pharmaceutical Name: Fructus Cnidii
Botanical name: Cnidium monnieri (L.) Cusson;Fructus Cnidii,Cnidium monnieri (L.) Cuss.
Common Name: Cnidium fruit (Shechuangzi),She Mi,She ChuangShi,SheSu,Wild Carrot Seeds,Ye Huluobo ZI.
Mongolia Name:HuXiGeTuReWu
Botanical Source: Common Cnidium Fruit is the dried ripe fruit of Cnidium monnieri (L.) Cuss.(Fam. Umbelliferae).
Source of Earliest Record: Shennong Bencao Jing
What's in Cnidium Monnier:Cnidium seed contains several compounds including coumarins, osthol, imperatorin, glucides and hepatoprotective sesquiterpenes.
Properties of Cnidium:Preliminary studies show some of the compounds in cnidium may have anti-histamine, anti-itch, anti-fungal, and anti-bacterial effects, along with having an influence on the pituitary-adrenocortex axis. Additional studies on rodents indicate that cnidium may improve bone strength (coumarins from fruits of cnidium inhibit formation and differentiation of multinucleated osteoclasts of rats). In rabbits, a compound found in cnidium called osthol or osthole was found to help relax the corpus cavernosa of the penis, which would potentially help with blood flow and erections. Cnidium may also have anti-cancer properties. As of September 2004, no human trials have been published on Medline regarding the clinical use of cnidium.
Availability of Cnidium:Cnidium is available in bulk powder, however cnidium is currently not easily found by itself. Cnidium is most often found in combination with other sex enhancing herbs in formulations.
Phytochemicals and Constituents of Cnidium monnieri:
Constituents: Cnidium fruit contains volatile oil consisting of pinene, carene, osthol, columbia- nadin, archangelicin, bergapten, edultin, isopimpinellin, etc.
Active compounds:
Osthole, Imperatorin, Bornyl isovalerate, Cnidimine, Xanthotoxin, Xanthotoxol, Isopimpinelline, Bergapten, Cnidiadin, Cniforin A, Dihydrooroselol, Columbianadin,berapten,cnidiadin,isopimpinellin,imperation, thymine,hypoxanthine,etc.
Main Phytochemicals:Osthole (C15H16O3),(2.0~3.0%);Xanthotoxin (C12H18O4); imperatorin (C16H14O4),(1.8%~2.2%).
Name:Osthol;Osthole:
Synoms of Osthole:Osthola,osthol,Osthol, osthenol,Ost,Cnidiadin,(C15H16O3),7-Methoxy-8-(3-methyl-2-butenyl)-coumarin; 7-Methoxy-8-isopentenylcoumarin; 8-(3-Methyl-2-butenyl)herniarin ; NSC 31868; Osthol;Osthole;Ostol; Ostole
Chemical Name:7-methoxy-8-isopentenoxycoumarin;
Systematic Chemical Name:2H-1-Benzopyran-2-one, 7-methoxy-8-(3-methyl-2-butenyl)-(9CI) ;Coumarin, 7-methoxy-8-(3-methyl-2-butenyl)-
Name of Substance:Osthol;Osthole
CAS No.:484-12-8
Molecular Formula:C15H16O3
Other Phytochemicals:palmitic acid;beta-sitosterol; edultin; 9-isobutyryloxy-o-actylcolumbianetin; cnidiosides A; cnidiosides B;cnidiol B;Cnidioside C; Cnidiol C. Volatile Oil(1.3%), contain 1-pinene;1-camphene;benzyl isovalerate; isoborneol;isopimpinelline; bergapten; columbianetin; columbianadin; cnidiadin; bornyl acetate;beta-eudesmol; imperation; thymine; hypoxanthine; uracil; L-(+)-valine;d-phenylalanine; etc.
Glucides of Cnidium monnieri fruit.From the fruit of Cnidium monnieri Cusson (Umbelliferae), two glucides were isolated together with other known glucides. Their structures were clarified as glycerol 2-O-alpha-L-fucopyranoside and D-quinovitol (6-deoxy-D-glucitol), respectively.
Brief Benefit of Cnidium monnieri formula:
1) Increased sexual drive and desire
2) Increased Nitric Oxide and cGMP levels
3) Increased blood flow to the sexual organs
4) Increased levels of the hormone responsible for sexual function
The Cnidium extracts from the plant Cnidium monnieri, which occurs in China and whose seed in the Chinese medicine is applied to many different kinds. Among other things the material also sexual Kraft supports, since it supports the production of nitrogen oxides and their receipt,and the final product increase the production of nitrogen oxide (NO) in the body, which restrains the PDE-5-Enzyme. The effect of the nitrogen oxides is extended by this process, which leads to a strong Erection. Viagra affects similar way. Please you note that also sometimes Cnidium extracts is sold for the treatment by ED. This does not work however long so effectively, since it finally acts thereby around nothing else as plant extract.
Reference:
1.What is Cnidium Monnier Extracts?Pharmacology Actions and application of Cnidium Monnier and Osthol,C15H16O3,Osthola?




