Cordyceps sinensis:The longevity and energy mushroom with history application for more than 3000 years.
Article Content:
- .Botanical Info of Cordyceps.
- .Introduction:Cordyceps sinensis.
- .Botanical Description.
- .Cordyceps Sinensis and Its History.
- .Phytochemicals and Constituents.
- .Cordyceps Sinensis and Its Benefits.
- .Cordyceps-History and Science.
- .Pharmacological and Clinical Research.
- .History,Traditional and Reported Uses.
- .Scientific Support and Functions.
- .Administration and Application Guide.
- .Story and Experience.
- .How search engine think about cordyceps.
- .Research Update: Cordyceps sinensis and Its findings.
Administration and Application Guide.
How much is usually taken?
The recommended intake of cordyceps is 3 to 9 grams taken twice daily as a liquid extract, as food, or as powdered extract.
Dosage 2-4 or 5~10 grams per day of cordyceps sinensis has been associated with increased energy levels, reduced fatigue and an enhanced ability to use oxygen.
Dosage:Talk with your caregiver about how much Cordyceps Sinensis you should take. The amount depends on the strength of the medicine and the reason you are taking Cordyceps Sinensis. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.
To store this medicine: Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.
Dosage Range:2 capsules (525mg each) (standardized extract), 2-3 times a day.
Most Common Dosage:2 capsules (525mg each) (standardized extract), 2 times a day.
Standardization:The most current available medical and scientific literature indicates that this dietary supplement should be standardized to 0.14% adenosine and 5% mannitol per dose.
Indications and Combinations:
Deficient kidneys manifested as impotence, seminal emissions and soreness and pain in the lower back and knees. Cordyceps (Dongchongxiacao) is used with Dogwood fruit (Shanzhuyu), Dioscorea (Shanyao) and Dadder seed (Tusizi). The herb can also be used alone.
Chronic cough and asthma or cough with bloody sputum due to lung deficiency. Cordyceps (Dongchongxiacao) is used with Glehnia root (Shashen), Donkey hide gelatin (Ejiao) and Tendrilled fritillary bulb (Chuanbeimu).
Spontaneous sweating and aversion to cold due to weakness of the body or illness. Cordyceps (Dongchongxiacao) is cooked with chicken, duck or pork.
Cautions and Contraindications:This substance should be used cautiously in cases with exterior syndromes.
Cordyceps Sinensis is a well known and important ingredient in Chinesemedicine. It is very widely used both in clinical medicine and as a householdremedy. In the Compedium of Materia Medica, the great classicof Chinese medicine, Cordyceps is described in detail and is consideredpotent at strengthening lung and kidneys, increasing energy and vitality,stopping hemorrhage, decreasing phlegm, and as an overall tonic. However, as the sourcing and gathering of the herb is rare and difficult, so its supply often falls short of demand.
Single herb is prohibited for yin deficiency and fire Hyperactivity, hemoptysis due to lung heat; and the patient who has heat in the exterior excess, anger, disharmony with liver qi and heat extreme in the blood phase are prohibited to use.
Safety Profile:
Toxicity in Animal Models Strain Cs-B414 produced an LD50 in mice of 27.26+-4.38 g/kg i.p. The p.o. tolerance dose was 252.5~300 g/kg.
No significant hematological toxicity was found in rabbits administered Cs-B414 at a dosage of 10 g/kg/day p.o. for 3 months. Neither kidney, liver, nor major organs showed significant toxicity compared to placebo-fed rabbits (Huang et al., 1987).
A 3-month, placebo-controlled, subacute toxicity study in both sexes of rats found the Cs-4 strain caused no toxicity or deaths at a dosage of 3 g/kg p.o. A 30-day, placebo-controlled toxicity study in mice found no signs of toxicity and no deaths from Cs-4. In both studies, organ weights and peripheral blood cells were not significantly different from those of the controls (Zhu et al., 1998a).
Acute toxicity(LD50):Cordyceps
Cordyceps Water Decoction.LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-mice.27.8 grams/kg
Cordyceps Water Decoction.LD50-Lethal dose,50 percent kill.Subcutaneou.Rodent-mice.38.0+-5.1 grams/kg
Cordyceps Fungus Water Decoction.LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-mice.17.9+-1.7 grams/kg
Cordyceps Fungus Water Decoction.LD50-Lethal dose,50 percent kill.Subcutaneou.Rodent-mice.17.1+-1.4 grams/kg
Cordyceps Mycelium Alcohol Decoction.LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-mice.35.2+-1.2 grams/kg
Cordyceps Mycelium Alcohol Decoction.LD50-Lethal dose,50 percent kill.Subcutaneou.Rodent-mice.24.5+-2.2 grams/kg
Cordyceps Sininesis Polysaccharides Oral Liquid.LD50-Lethal dose,50 percent kill.Oral.rodent-mice.LD50 >10 000 mg/kg
Reference:to Study the acute and subchronic toxicity of the cordyceps sininesis polysaccharides oral liquid.NIE Mu-hai,ZHANG Quan-xin,ZHU Mao-cheng,MODERN PREVENTIVE MEDICINE.2005 Vol.32 No.9 P.1062-1063
Are there any side effects or interactions?
There are insufficient studies on the safety of cordyceps. However, it has a long history of use as a food and is generally considered safe. There is no information available about safety in pregnancy, lactation, or use in children.
There are two reported cases of lead poisoning associated with the use of apparently contaminated cordyceps powder. Cordyceps should only be purchased from companies that test to exclude heavy metal contamination.
At the time of writing, there were no well-known drug interactions with cordyceps.
Warnings:
Before taking Cordyceps Sinensis, tell your doctor if you are pregnant or breastfeeding
Use with caution if you have diabetes, as Cordyceps Sinensis can lower blood sugar.
Before Using: Tell your doctor if you ...
are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
are pregnant or plan to become pregnant while using this medicine
are breastfeeding
have a history of depression, breast cancer, have pheochromocytoma, or ulcers
have any other health problems, such as high blood pressure or heart or blood vessel disease.
Possible Side Effects:
Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.
Breathing problems or tightness in your throat or chest
Chest pain
Skin hives, rash, or itchy or swollen skin
Other Possible Side Effects:
You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.
Low blood sugar (hypoglycemia).
Upset stomach and dry mouth.
Quality control:
The finger-print of water-solubility ingredient in Cordyceps sinensis and silkworm cordyceps.
Toxicities and Precautions:
Be sure to tell your pharmacist, doctor, or other health care providers about any dietary supplements you are taking. There may be a potential for interactions or side effects.
This dietary supplement from reputable manufacturers is considered safe when used in accordance with proper dosing guidelines. There have been two case reports of lead poisoning from supplementation with apparently contaminated cordyceps.
If you are planning to have any type of surgery or dental work, stop using this dietary supplement for at least 14 days prior to the procedure.
Health Conditions:If you have a bleeding disorder talk to your doctor before taking this dietary supplement.
Pregnancy/Breast-Feeding:To date, the medical literature has not reported any adverse effects related to fetal development during pregnancy or to infants who are breast-fed. Yet little is known about the use of this dietary supplement while pregnant or breast-feeding. Therefore, it is recommended that you inform your healthcare practitioner of any dietary supplements you are using while pregnant or breast-feeding.
Age Limitations:To date, the medical literature has not reported any adverse effects specifically related to the use of this dietary supplement in children. Since young children may have undiagnosed allergies or medical conditions, this dietary supplement should not be used in children under 10 years of age unless recommended by a physician.
Reference:
1.Cordyceps sinensis:The longevity and energy mushroom with history application for more than 3000 years.
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