What is danshen?What is Tanshinone IIA?Application and function of Tanshinone IIA.Modern Developments and application research of Radix Salvia miltiorrhiza.

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Active Constituents and phytochemicals of Radix Salvia miltiorrhiza(Danshen).

Radix Salvia miltiorrhiza Salvia miltiorrhiza B red sage root Dan Shen Tanshinones Tanshinone IIA photo picture image The main active constituents of salvia are diterpene quinones, known as tanshinones (the Wade-Giles transliteration of danshen is tan-shen, hence the quinones were called tanshinones). Most of these compounds are colored, providing the reddish appearance of the roots. The group of components, labeled tanshinone I, tanshinone II, cryptotanshinone, etc. (see Figure 3), were first described by researchers in 1968, though investigations had been underway since the pigments were isolated from salvia in 1934. More recently, nearly 40 variants of the basic tanshinone structures have been found in the roots. The tanshinones are unique chemical constituents, and similar compounds are not found in other Chinese herbs. The total tanshinone content of the roots is about 1%, with tanshinone I and II and cryptotanshinone being present in the largest amount. In one recent study, the concentration of Radix Salvia miltiorrhiza yielded tanshinone II 0.29%; cryptotanshinone 0.23%; tanshinone I: 0.11%.

 The primary active constituents of Radix Salvia miltiorrhiza(Danshen):

 Cryptotanshinone Photo Picture imageTanshinone i Photo Picture image
 tanshinone ii Photo Picture imagetanshinone vi Photo Picture image

 The isolated tanshinones have been shown to inhibit bacteria, reduce fever and inflammation, inhibit platelet aggregation, dilate the blood vessels, and aid urinary excretion of toxins,also many other good benefits.

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citations1.What is danshen?What is Tanshinone IIA?Application and function of Tanshinone IIA.Modern Developments and application research of Radix Salvia miltiorrhiza.

last edit date:29th,April.2009.