What is Echinacea Purpurea?Good function and application of Polyphenols and Chicoric acid from Echinacea Purpurea Extract?

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Dosage of related extracts.

Echinacea Extract ECHINACEA PURPUREA ROOT EXTRACT;ECHINACEA PURPUREA EXTRACT Echinacea angustifolia,Coneflower extract 289-808-4 90028-20-9 Chicoric acid,dicaffeoyltartaric acid.CAS.NO:70831-56-0 photo picture image Because of the existence of many different types of Echinacea preparations, and the presence in various preparations of more than one immunologically-active class of constituents, firm recommendations regarding dosage are difficult to make. In a recent review, Wagner (1997) advised that for oral administration the best response is obtained from allopathically prepared alcoholic tinctures or homeopathic mother tinctures, up to a dilution of D2. Tinctures are taken in doses of 30 to 40 drops, 3-4 X/day for a period of at least 5-6 days at the onset of acute infections. Wagner added that for prophylaxis, longer treatment times (4-6 weeks), including short intervals (4-5 days) of non-treatment, provide better results than continuous treatment.
 The British Herbal Compendium recommends a dosage of 1 g of dried root (Echinacea angustifolia), or 2-5 mL of a 1:5, 45% ethanol tincture, 3 X/day (Bradley, 1992).
 Murray (1995) suggests the following doses: dried root or as a tea, 1-2 g, 3 X/day; freeze-dried plant, 325-650 mg, 3 X/day; juice of aerial portion of Echinacea purpurea stabilized in 22% ethanol (preferably standardized to contain a minimum of 2.4% b-1,2-fructofuranosides), 2-3 mL (= 0.5-0.75 tsp.), 3 X/day; tincture (1:5), 3-4 mL (= 0.75-1.0 tsp.), 3 X/day; fluid extract (1:1), 1-2 mL (=0.20-0.25 tsp.), 3 X/day; solid dry extract (6.5:1 or 3.5% echinacoside), 100-250 mg, 3 X/day.
 Commercial extracts of Echinacea angustifolia and E. purpurea sold in the United States have commonly been standardized to contain echinacosides and 4-sesquiterpene esters (Flynn and Roest, 1995). More recently, Bauer (1998) suggested that the active substances in Echinacea that may be best utilized as standards are caffeic acid derivatives such as echinacoside and cichoric acid, and other substances; especially polysaccharides, glycoproteins, alkamides, and polyacetylenes. In an analysis of 6 commercial E. purpurea expressed juice preparations, Bauer (1999) found alkamide concentration ranged from 0.1-1.8 mg/mL and chicoric acid from 0.0-0.4%.
 Pediatric:Adjust the recommended adult dose to account for the child's weight. Most herbal dosages for adults are calculated on the basis of a 150 lb (70 kg) adult. Therefore, if the child weighs 50 lb (20 to 25 kg), the appropriate dose of echinacea for this child would be 1/3 of the adult dose.
 Use alcohol-free preparations for children.
 Adult:For general immune system stimulation, during colds, flu, upper respiratory tract infections, or bladder infections, choose from the following forms and take three times a day:
 1 to 2 grams dried root or herb, as tea
 2 to 3 mL of standardized tincture extract
 200 mg of powdered extract containing 4% phenolics
 Tincture (1:5): 1 to 3 mL (20 to 90 drops)
 Stabilized fresh extract: 0.75 mL (15 to 23 drops)
 For slow-healing wounds, creams or ointments should be applied as needed.

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citations1.What is Echinacea Purpurea?Good function and application of Polyphenols and Chicoric acid from Echinacea Purpurea Extract?

last edit date:28th,April.2009.