Bencao Gangmu noted "West River North exist lascivious Goat,make coition hundreds times daily,for the cause of taking this weed,so named goat weed. This kind of grass also named three branches-nine leaves grass,for the 3 branches steps from stem, then 3 leaves stems from each branches.leaves and stem can be remedy use."
Horny Goat Weed has been used as an aphrodisiac for hundreds of years, and research has also proven its effects on improving sexual desire and performance. Research has shown that Horny Goat Weed can inhibit an enzyme called acetylcholinesterase (AChE). AChE rapidly stops neurotransmission at cholinergic synapses like those found in the brain and at neuromuscular junctions, which are needed for speedy responses in the neuromuscular system.By inhibiting AChE,Horny Goat Weed supports higher levels of the key cholinergic neurotransmitters associated with sexual arousal.
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Basic Instruction
What is icariin or Horny Goat Weed Extract?Does Horny Goat Weed and Icariin Work for Erection?How does icariin mime testosterone?
seminal trace...Epimedium Extract.Horny Goat Weed Extract.Icariin.CAS.NO:489-32-7.M.F.C33H40O15.Epimedium brevicornum Maxim Extract.Icariine,Epimedium sagittatum,Epimedium Leaf Extract.Epimedium extract powder,Epimedium Alcohol Water Extract.icariin,Power of Love,Super Penis Enlarges,improves the kidney function,solves impotence and the early ejaculation,small penis,prostate diseases,sterility of long marriage,male and female frigidity,awkwardness,pains of having sex,spermatorrhoea,sore wrist and feet,poor sleep and memory,mentally depression, baldness,white hairs,middle aged and older male adults who are physically weak with a kidney dysfunction,penis shrinking and shortening,early ejaculation,scarce sexual needs etc...
Botanical info of Horny Goat Weed or Epimedium:
Common names: Horny Goat Weed,Horny Goat Grass,Xianlingpi,Herba Epimedii,Epimedium Herb.
Botanical Source:Epimedium brevicornum Maxim.;Epimedium sagittatum (Siebold. et Zucc.) Maxim., Epimedium koreanum Nakai.,Epimedium pubescens Maxim.,Epimedium sinense, Epimedium wushanense T.S.Ying.
Synonyms:Shorthorned Epimedium Herb extracts; Epimedium segittatum (Sitb.et Zucc.) Maxim extracts;Horny Goat Weed,Lusty goat herb,etc.
PinYin Name:Xianlingpi;Xianlingpi alludes to the immortals' intelligent nature (pi refers to the spleen, which is, according to the Chinese, the source of wisdom); this name appears to have been a popular designation for the herb that was originally called yinyanghuo.
Plant Part Used: Branches and Leaves.
Extract Solubility:soluble in water and ethanol. soluble excelent in alcoholic drink.
This herb is the dried leaf of Epimedium brevicornum Maxim.;Epimedium sagittatum (Siebold. et Zucc.) Maxim., Epimedium koreanum Nakai.,Epimedium pubescens Maxim.,Epimedium sinense, Epimedium wushanense T.S.Ying.,of the barberry family (Berberidaceae). Native to east Asia, the plant is grown on hillsides in damp shady bamboo groves or in moist woodlands in China.
The perennial plant grows to about 0.5 m by 0.4 m. The leaf is in the shape of an arrowhead, thus the word "sagittatum," which means arrowhead shaped. It is in flower from May to June. The flowers are hermaphrodite (have both male and female organs). The plant can grow in semi-shade (light woodland). It requires dry or moist soil.
Epimedium is often cultivated as a ground cover, and chosen among herbs to be planted in the informal woodland garden in the West for informality and naturalness. The Chinese, however, use it as a yang tonics in traditional Chinese medicine.
In China, epimedium is produced mainly in the provinces Shannxi, Liaoning, Shanxi, Hubei, Sichuan, and Guangxi. It is collected in summer and autumn when the stem and leaves are exuberant, and dried in the sun following removal of impurities.
Phytochemicals and Constituents of Herba Epimedii:
Main Content: icariin. C33 H40 O15.
Synonyms:Icariine; -((6-Deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
Formula: C33 H40 O15. Molecular Weight: 674.69 CAS RN:489-32-7
Chemical Name:3-((6-deoxymannopyranosyl)oxy)-7-(glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one
CAS Type 1 Name:4H-1-Benzopyran-4-one, 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-butenyl)-
Horny Goat Weed Archeology:How did Horny Goat Weed get its name?:
Horny Goat Weed is also called Ying Yang Huo in Chinese, and has been used to treat kidney, joint, liver, and back disorders, and it's also used as an aphrodisiac. Horny goat has testosterone like effects, stimulating sexual activity, desire,increases sperm production, and stimulates sensory nerves.
Centuries ago, Chinese goat farmers noticed that both their younger¡and older goats experienced sexual rejuvenation after eating the Epimedium plant¡or, in more general terms, Horny Goat Weed.Horny goat weed (Epimedium) is a pungent ornamental herb found in Asia and the Mediterranean. The Chinese call it Yin Yang Huo, which loosely means "licentious goat plant." Legend has it that the name came from a herder who noticed his goats becoming more sexually active after eating the plant. Supplement companies have adopted the provocative name by which it is known in the U.S.
Horny Goat Weed and folk Physician Tao Hongjing:
What about the details of the legend described following: During the South North and Dynasties of Ancient China, Goatherd and farmers noticed occasionally when herd in field,that everytime after the Goat or Sheep chew some small grass,the male Goat oestrust more times and the Goat penis erect hard and long, intercourse and mating with female Goat more times daily, and period last longer. So some Goatherd talk this case to a folk Physician,this Physician is the Great Pharmacist of the South North and Dynasties of Ancient China,his name is Tao Hongjing (A.D.451~536,famous of Taoism,Physician,Alkamie.would-be named Brightly Lit or Hua Yang Hermit),Physician Tao Hongjing investigate this case with Goatherd times fieldly and identify this grass with properties of Yang Boosting,and later he began to put this grass into remedy for treatment of patient with erection dysfunction,good result proved after orally dosed,and this bring another good fame for Physician Tao Hongjing. For the grass can make male goat or the horny goat more enegy and coition,so it was called Horny Goat Grass or Horny Goat Weed ever then.
Horny Goat Weed from Bencao Gangmu:
Bencao Gangmu noted "West River North exist lascivious Goat,make coition hundreds times daily,for the cause of taking this weed,so named goat weed. This kind of grass also named three branches-nine leaves grass,for the 3 branches steps from stem, then 3 leaves stems from each branches.leaves and stem can be remedy use."
Etymology or Name origin of "Epimedium":
The plant was named epimedium because it is similar to a plant found in the ancient Asian kingdom of Media, now a part of Iran. Epimedium is a genus of many related plant species and some are used for medicinal purposes, including Epimedium sagittatum, Epimedium brevicornum, and Epimedium koreanum. Although this herb has a history of traditional use for disorders of the kidneys, joints, and liver, its principle use is as an aphrodisiac and to combat fatigue.
A great deal of research has been done in recent years concerning human sexual performance and libido drive. Some of that research have focused on natural, botanical ingredients which have legendary history as natural aphrodisiacs, and Horny Goat Weed is among the top performers. Horny Goat Weed is a low growing, deciduous perennial with leathery leaves (up to 1 foot long) spreading by underground stems. The flowers of this plant are 1 to 2 inches wide, resemble a bishop's hat (pendent-shaped), have long spurs, and come in various colors (purple, pink, yellow or white).
Mechanism of Action:How Does Horny Goat Weed and Icariin Work?:Icariin act as super AChE inhibitor and libido Stimulator. Horny Goat Weed's combination of botanical ingredients may enhance sexual performance through a variety of mechanisms such as increased testosterone production, increased energy and increased sexual hormone production. ( See Clinical Trials)
Many of the herbs contained in Horny Goat Weed have been used in traditional botanical medicine in China, South America and Ayruveda.
Epimedium contains a compound known as lcariin that helps stimulate the nerves throughout the body. Advanced studies reveal that this stimulation effect is particularly experienced in the genital area of the body.
Horny Goat Weed has been used as an aphrodisiac for hundreds of years, and research has also proven its effects on improving sexual desire and performance. So how does Horny Goat Weed work? Research has shown that Horny Goat Weed can inhibit an enzyme called acetylcholinesterase (AChE). AChE rapidly stops neurotransmission at cholinergic synapses like those found in the brain and at neuromuscular junctions, which are needed for speedy responses in the neuromuscular system. By inhibiting AChE,Horny Goat Weed supports higher levels of the key cholinergic neurotransmitters associated with sexual arousal.
It is a robust all-natural stimulant that can support a more robust life as well as love-life
The leaves of the plant contain a variety of flavonoids, polysaccharides, sterols and an alkaloid called magnoflorin. Many cultures have reported that Horny Goat Weed supports increased libido, improved erectile function, and relief from menopausal discomfort. While the scientific community has focused mainly on men and treatments for erectile dysfunction, women's sexual performance and loss of sex drive (among both sexes) are also hot issues today.
Mechanism study:the therapeutic action of icariin on erectile dysfunction(ED):
Some clinical researchers do research and showed PDE5 was isolated from the human platelet and PDE4 from the rat liver tissue using the FPLC system (Pharmacia, Milton Keynes, UK) and the Mono Q column. The inhibitory effects of icariin on PDE5 and PDE4 activities were investigated by the two-step radioisotope procedure with [(3)H]-cGMP/[(3)H]-cAMP. Papaverine served as the control drug.
Icariin and papaverine showed dose-dependent inhibitory effects on PDE5 and PDE4 activities. The IC(50) of Icariin and papaverine on PDE5 were 0.432 micromol/L and 0.680 micromol/L, respectively and those on PDE4, 73.50 micromol/L and 3.07 micromol/L, respectively. The potencies of selectivity of icariin and papaverine on PDE5 (PDE4/PDE5 of IC(50)) were 167.67 times and 4.54 times, respectively.
And icariin is a cGMP-specific PDE5 inhibitor that may be developed into an oral effective agent for the treatment of ED.
Horny Goat Weed and Icariin:An All Natural Salvation For Male&Female Happiness:
The Chinese, the worlds leading herbalists, are famous for their healing ability exemplified by their longevity and virility. Most Americans are under the impression that ginseng is the only sexual stimulant in the Chinese healing arsenal. This is far from the truth, Fo Ti, Deer Antler, Rhinoceroses Horn are among the plethora of Chinese Herbal Stimulants.
Western scientists have been alerted to a potent Chinese sexual enhancer - epimedium sagittatum - commonly known as Horny Goat Weed. Horny Goat Weed stimulates the nerves throughout the entire body especially n the genital area according to researchers. Desire is also increased along with erectile function, increased testosterone levels, androgen like influence on the testes, prostate and important sexual muscles. The Chinese Academy of Sciences recommend the regular use of Horny Goat Weed to slow the aging process, as it improves the quality of life.
Horny Goat Weed was discovered by Chinese goat farmers who observed old "over the hill" goats sexual rejuvenation after eating the large thorn covered weeds that other animals avoided, hence the reason for the name.
So,Substitution and Libido Stimulator are always necessary,Let's try Horny Goat Weed and Icariin,the natural wonders in gods phamacopia and a natural alternative to Viagra. It has been proven safe and it willl improve the enjoyment and quality of our lives.
Horny Goat Weed Series base for extending and Strong Your Imagination and Ability both As Man or As Women,that means Icarrin Not Only for Eva,But Also For Adam.
Horny Goat Weed and its Traditional Applications:
Being sweet and warm, it can tonify the kidney and invigorate yang; being pungent and warm, it can also dispel pathogenic wind and dampness. Being stronger in tonifying the kidney and strengthening uscles and bones, it serves to treat syndromes of impotence due to kidney-deficiency, infertility due to uterine coldness, wind-dampness with arthralgia, and weak extreties. In spite of weaker dryness than Rhizoma Curculiginis, it still can pair yin and help yang. So it should be used cautiously.
1. For lumbago due to kidney-deficiency, impotence and infertility due to sperm coldness, it is often used with Fructus Lycii, Radix Morindae Officinalis, Radix Rehmanniae Pareparata, Radix Acontit, etc., to tonify the kidney, strengthen yang and supplement esssence and blood.
2. For climateric irregular menstruation, fluctuation of blood pressure, and functional uterine bleeding in the type of deficiency of kidney-yang, it is often used with Rhizoma Curculiginis, Radix Angelicae Sinensis, Rhizoma Anemarrhenae and Cortex Phellodendri to regulate and tonify yin and yang, and to nourish blood and modulate menstruation.
3. For chronic arthralgia, low immunity, cold pain and lassitude in the loins and knees, it is often used with Radix Morindae Officinalis, Ramulus Loranthi, Radix Achyranthis, Cortex Eucommiae, Radix Dipsaci, etc., to dispel wind-dampness and strengthen muscles and bones.
Modern Researches:
Epimedium has androgenic (related to male sex hormone) effect. Its liquid extract (especially that made from its leaves and roots) can promote seminal secretion in dog. It can inhibit cardiac contractility. The preparation of this herb can obviously increase the coronary flow in both vivo and vitro. It also can dilate peripheral blood vessels, increase the blood flow of extremities and improve the micro-circulation.
Unlike the many herbs that have estrogenlike effects, epimedium is an unusual herb in that it has testosteronelike effects. It stimulates sexual activity in both men and women, increases sperm production, stimulates the sensory nerves, and increases sexual desire. This herb increases blood flow to the penis and also prevents a protein called fibrin from being deposited on capillary walls, thus preventing loss of sexual function in men with atherosclerosis. Epimedium's testosteronelike actions also allow it to fight the muscle wasting experienced by many people with AIDS. In laboratory tests, chemical components of the herb even act against human immunodeficiency virus (HIV) itself.
Its decoction, alcohol extract and methyl alcohol extract all have significant and lasting hypotensive action when intravenously injected into the rabbit. It also has bacteriostatic effect, obviously on poliovirus, mildly on staphylococcus albus and staphylococcus aureus, and also on enterovirus and Mycobacterium tuberculosis. It also has effects of raising mice's tolerance on hypoxia (a deficiency of oxygen reaching the tissues of the body), lowering blood sugar and blood lipid, inducing diuresis, arresting cough and expectorating (ejecting from the throat or lungs).
Used as a kidney tonic, epimedium also treats sterility and barrenness. It is taken internally for a number of ailments, including asthma, bronchitis, cold or numb extremeties, arthritis, lumbago, impotence, involuntary and premature ejaculation, high blood pressure and absentmindedness.
Affecting the cardiovascular system:
The heart: Experiments show that, to varying degrees, non-amino acid components of alcohol-based extract of Yin Yang Huo improves the subjects' myocardial ischemia and EKG readings, and that Yin Yang Huo increases coronary blood flow, decreases heartbeat rate, and improves myocardial ischemia tolerance.
Blood pressure: Yin Yang Huo lowers the blood pressure by one of the following mechanisms: 1) effecting a sympathetic block; 2) counteracting endogenous catecholamine; 3) dilating arteria coronaria, arteria femoralis, and cerebral vessels; and 4) blocking the ROC and PDC Ca2+ channels of vascular smooth muscles.
Blood rheology: Experiments on rabbits show that Yin Yang Huo lowers whole blood viscosity and inhibits red blood cell aggregation. In a healthy person, Yin Yang Huo significantly lowers the rate of ADP-induced blood platelet aggregation, inhibits blood platelet aggregation reaction, and lengthens blood zymogen coagulation time.
Arrhythmia: Administered by vena jugularis injection at the dosages of 60mg/kg and 120mg/kg, the total flavone glycoside of Epimedium koreanum Nakai can significantly counteract barium chloride-induced arrhythmia in hamsters and adrenaline-induced arrhythmia in guinea-pigs.
Effects on the immune system:
Regulating macrophage: Yin Yang Huo, Yin Yang Huo polysaccharide, and Yin Yang Huo glycoside can enhance the function of mice's abdominal macrophage. Under LPS stimulation, they can also promote IL-1 and TNF production by mice's abdominal macrophage to stimulate.
Regulating T-lymphocytes: Administered to mice with cyclophosphamide-impaired immune systems, Yin Yang Huo can restore their ANAE to the normal level, and increase the permeating ability of their thymocyte 3H-TdR.
Regulating B-lymphocytes: Experiments show that Yin Yang Huo can promote antibody production in hydrocortisone- and hydroxyurea-treated mice (i.e., mice whose immune system has been inhibited).
Regulating NK and LAK cells: Yin Yang Huo can significantly enhance the activity of NK cells in senile hamsters; similarly, it can enhance the activity of LAK cells, and act synergistically with IL-2.
Anti-aging effects: Yin Yang Huo can enhance the activity of LH, FSH, T, E2, and IL-2 and NKC.
Anti-inflammatory effects: Yin Yang Huo can significantly lower the prostaglandin E content in inflammation exudate, enhance erythrocyte catalase activity in mice, inhibit ear swelling in mice with the adrenal grand removed, and does not significantly affect the weight of the adrenal gland or the vitamin C level in hamsters.
Promoting fracture recovery: Administered to patients with fractures, Yin Yang Huo can promote hematoma polarization and absorption, cartilaginous calcification, callus growth, porotic bridging and rebuilding, and increase both the number and activity of cells of fractured bones.
Horny Goat Weed Research and case study:
Effect of Horny Goat Weed Herbal Complex Supplement on Sexual Satisfaction in Healthy Men and Men Treated with Viagra Clinical Trial.There have been much research done on Horny Goat Weed, and its aphrodisiac effects have been well demonstrated in animals and humans.
Purpose: We examine the effects of an herbal complex product on sexual satisfaction in healthy male volunteers and male volunteers who use Viagra.
Methods: In this study, 25 healthy men (HM) and 13 men (VM) who used Viagra were assigned to initially receive daily therapy for 45 days with two capsules (808 mg x 2) of a commercially-prepared herbal complex of epimedium grandiflorum, maca pure (lepidium meyenii), mucuna pruriens, and polypodium vulgare . An additional four capsules (3232 mg) were taken one to two hours prior to sexual activity to determine its effect on sexual interest, sexual performance, and overall sexual satisfaction. After 45 days, the double-blind phase of the study began with a placebo product and active product randomly given to healthy men (HM) who had reported a positive response and taken for two weeks to four weeks. All subjects were evaluated after the first 45 days of treatment and finally after 60 days.
Results: 13 of 20 HM had a positive response to the herbal mixture and 6 of the 13 VM had a positive response to the herbal mixture. In the double-blind placebo portion of the study, no HM had a positive response to placebo product; 6 of the 7 HM had a positive response to the active product.
Conclusions: Daily use of the herbal complex for a minimum of 45 days resulted in an enhancement of sexual satisfaction in 60 percent of healthy male subjects and 45 percent of men using Viagra. The exact mechanism of action of the herbal mixture is unknown although it may have a testosterone-like effect.
More Case Study:
In a study done by Steven Lamm, M.D, 38 men were administered 2 capsules (2 X 800mg) of herbal complex of epimedium grandiflorum, maca pure (lepidium meyenii), mucuna pruriens,and polypodium vulgare (in short, Horny Goat Weed) for 45 days:25 were healthy men and 13 were men already taking Vi agra. Another 4 capsules of Horny Goat Weed were taken 1 to 2 hours prior to sexual activities.
The study found 13 of 20 healthy men responded positively to Horny Goat Weed, and 6 of the 13 men already on Viagra also had a positive effect from using Horny Goat Weed. In most cases, the men reported overall improvement in sexual satisfaction and increase in sexual desires.
Rabbit corpus cavernosum case study:
Scientific study about the relaxation effects of icariin(C33H40O15,MW:676.67) on rabbit corpus cavernosum (CC) were investigated by in vitro study and the effects of icariin on erectile function of rats and the effects of icariin on cGMP formation and PDEs activity were investigated by in vivo study. The effects of 4 weeks oral administration of icariin (Dosage:1mg/kg/day, 5mg/kg/day) on castrated rats ED model and vasculargenic ED model were investigated too.
icariin showed a dose dependent relaxation effects on CC of rabbit and the relaxation effects of icariin on CC were significantly inhibited by pre-treating NOS inhibitors (LNNA) and gunylate cyclase (GC) inhibitors (ODQ) by in vitro study and icariin significantly increased ICP rats without influence on MBP by in vivo study. icariin also showed specific inhibiting effect on cGMP specific PDE5 compared with other PDEs. Four weeks oral administration of icariin could enhance erectile function (ICP) of castrated and vasculargenic rats ED models with increasing NOS and isoform mRNA and protein expression in CC compared to controls.
icariin showed selective inhibiting activity on cGMP specific PDE5 and enhancing erectile function after 4 weeks oral administration in castrated and vasculargenic ED models with regulation of NOS mRNA and protein expression in CC.
icariin mime testosterone study.:
To evaluate the testosterone mimetic properties of icariin.Forty-eight healthy male Sprague-Dawley rats at the age of 15 months were randomly divided into four groups with 12 rats each: the control group (C), the model group (M), the icariin group (ICA) and the testosterone group (T). The reproductive system was damaged by cyclophosphamide (intraperitoneal injection, 20 mg/kg x day) for 5 consecutive days for groups M, ICA and T, at the sixth day, ICA (gastric gavage, 200 mg/kg x day) for the ICA group and sterandryl (subcutaneous injection, 5 mg/rat . day) for the T group for 7 consecutive days, respectively. The levels of serum testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH), serum bone Gla-protein (BGP) and tartrate-resistant acid phosphatase activity in serum (StrACP) were determined. The histological changes of the testis and the penis were observed by microscope with hematoxylin-eosin (HE) staining and terminal deoxynucleotidyl transferase biotin-dUTP-X nick end labeling (TUNEL), respectively.
Experiment above got result effectively as following expressions:
(1) Icariin improved the condition of reproductive organs and increased the circulating levels of testosterone.
(2) Icariin treatment also improved the steady-state serum BGP and might have promoted bone formation. At the same time, it decreased the serum levels of StrACP and might have reduced the bone resorption.
(3) Icarrin suppressed the extent of apoptosis of penile cavernosal smooth muscle cells.
Conclusion was made that Icariin has testosterone mimetic properties and has therapeutic potential in the management of hypoandrogenism.
Experimental study on antagonizing action of herba Epimedii on side effects induced by glucocorticoids::
The experimental result has shown that the water extract of Herba Epimedii (Epimedium sagittalum) works very well in preventing and curing the side effects induced by long-term use of glucocorticoids in rats, especially in antagonizing adrenocortical atrophy and osteoporosis.
Cautions,Side Effects and Acute Toxicity of Horny Goat Weed.:
No major side effects have yet been discovered. In very high doses, horny goat weed may have a stimulatory effect and may cause sweating or feeling hot.
There are no documented, undesirable Horny Goat Weed side effects. In the study mentioned above, no side effects were noticed in any of the participants. However, many positive side effects (or benefits) were noted:
Increases Sexual Drive:The men reported a increase in desire to engage in sexual activity.
Increases Sexual Satisfaction:The men noted overall increase in satisfaction with their sex life.
Some men also reported a increase in their partner's satisfaction - presumably from their improved performance.
Increases Stamina,Increases Sensitivity and Increases Confidence.
Are there any side effects or interactions?
In traditional Chinese medicine, horny goat weed is usually combined with yin tonic herbs when used long term for support of sexual health. If this is not done, it is believed the herb could cause problems such as aggressiveness, irritability, fever, or other hot symptoms (such as racing heart beat). In animal studies, prolonged use of excessive amounts of horny goat weed was associated with decreased thyroid activity.
Horny Goat Weed:Dosage and Availability
The ideal dosage of horny goat weed is not known, but may range from 1 to 3 grams per day. Capsules or tablets are sold in various doses, ranging from 250 to 500 mg. Some products are standardized to a flavonoid called icariin, which has been found to be protective of liver.
The traditional use of horny goat weed is as a hot-water decoction (tea), which results in a different set of active constituents when compared to the alcohol extracts that are more commonly used in commercial products. It is difficult to know which form is best suited as an aphrodisiac.
How much is usually taken?:Traditionally 5 grams (1 tsp) of horny goat weed was taken three times per day, usually after being simmered (decocted) in 250 ml (1 pint) of water for 10 to 15 minutes. A similar amount can be taken in the form of granules, which are freeze-dried grains made from decocted herb, or powdered herb in capsules.
Safety and Acute toxicity:
Icariin Acute toxicity(LD50):
LD50-Lethal dose,50 percent kill. Intraperitoneal. Rodent-mouse, 80gm/kg.
IC50:Lethal dose,50 percent kill.Chinese hamster lung cells: 55.4 mg/ml.
IC50:Lethal dose,50 percent kill.Chinese hamster ovary cells: 19.53 mg/ml.
Negative result get from genotoxicity experiments including mice bone marrow micro-nuclear test, Ames test and TK gene test.
Reference:Carcinogenesis,Teratogenesis and Mutagenesis.2006 Vol.18 No.6 P.439-442.The Safety Evaluation of Herba Epimedii Water Extract.by SUI Hai-xia.GAO Peng.XU Hai-bin.
Summary
Horny goat weed is likely to make you horny. Don't expect much the first or second day of use. Most users will notice a mild to moderate effect on the third or fourth days.
Poor bedroom performance and sexual dysfunction are unfortunate, but trust me, THERE IS SOMETHING THAT CAN BE DONE TO HELP. It won't cost you an arm and a leg, and it won't jeopardize your health and safety. In this article, my goal is to show you the way to the sex life you've only dreamed about . . . until now.
So please read on.
In recent studies, a daily dose of Horny Goat Weed extract has shown significant results as a sexual performance enhancer for both men and women - boosting sexual energy & stamina.
Horny Goat Weed lowers blood pressure by dilating capillaries and blood vessels while slowing the adrenal production that can hinder blood flow to the sex organs.
Men achieve better erections due to this effect and it is thought that women benefit from the increased blood flow as well, and perhaps from other testosterone-like alkaloids and sterols within the plant.
Research has also shown that Horny Goat Weed significantly increases testosterone in mice. Horny Goat Weed is a traditional Chinese herb of long-standing use by those in the health care profession, where it has been used in the past to relieve liver, joint, knee, and back problems.
Let me briefly explain why so many males suffer from sexual dysfunction.From a biological anthropological standpoint, the male's job is to impregnate as many females as possible, which increases the chance that he will successfully pass his genes on to the next generation. It is therefore of benefit if ejaculation occurs rapidly so he can move on to the next mate. Now what this means is that once the job is done, there is no need for further sexual interaction.
Unfortunately, this usually leaves the female unsatisfied and displeasured.This is because biologically, women are programmed completely differently than men. their job is to ensure that the male's semen is passed on-otherwise, child rearing would be impossible.
his is why women have such an insatiable appetite for orgasms . . . continuation of the human race depends on her lasting at least as long as the male!
OK - enough scientific jargon. Now let's talk about what we can do to help you improve your sexual performance and erectile potential. The bottom line is that to satisfy your woman, you need to match her stamina with a strong, solid, long enduring erection.
Horny Goat Weed----Get ready to heat up your love life!
A Tradition from Erxian Tang: Two Immortals Decoction?:
The Two Immortals Decoction has an intriguing name. Who are these immortals? And, why is the formula named after them?
Two (er = two) of the formula ingredients in the six herb formula Erxian Tang have xian in their names: curculigo (xianmao) and epimedium (xianlingpi), explaining, most simply, how the formula got its title. There are other formulas named in this way, such as Erdong Tang, comprised of ophiopogon (maimendong) and asparagus (tianmendong). But, in that case, the name is not so interesting: dong (= winter) was used in the name for ophiopogon because the plant doesn't wither in winter; it was used in the name for asparagus because of the similarity of its uses to that of ophiopogon. In the case of curculigo and epimedium, the common term xian (= immortal) applies to an important part of Chinese culture.
Xianmao was named in the Bencao Gangmu (by Li Shizhen; 1596) as one of the herbs believed to contribute to immortality. This property was described as making the body lighter when taken over a period of time (the mao portion of the name refers to the spear shaped leaves). Xianlingpi alludes to the immortals' intelligent nature (pi refers to the spleen, which is, according to the Chinese, the source of wisdom); this name appears to have been a popular designation for the herb that was originally called yinyanghuo (which describes it as an aphrodisiac).
The Taoists who undertook the effort to become immortals were thought to become lighter and lighter, until they could float up into the clouds. This, and other changes, was brought about by their meditations in seclusion and their ingestion of elixirs prepared in secret. The Chinese character for xian (immortal) is the combination of man and mountain: it refers to the mountain dwelling Taoists.
Around 100 B.C., a poem about attaining immortality, the ode Yuan Yu (Journey to Remoteness, or Roaming the Universe) was written. It depicts the transition to immortality thus:
Having heard the precious teaching, I departed,
And swiftly prepared to start on my journey.
I met the feathered ones at Cinnabar Hill,
I tarried in the ancient Land of Deathlessness.
In the morning, I washed my hair in the Hot Springs of Sunrise,
In the evening, I dried myself where the suns perch.
I sipped the subtle potion of the Flying Springs,
And held in my bosom the radiant metallous jade.
My pallid countenance flushed with brilliant color,
Purified, my jing began to grow stronger;
My corporeal parts dissolved to a soft suppleness,
And my spirit grew lissome and eager for movement.
The writer then describes clinging to a cloud and riding aloft on it, to "the very spheres of the storied heavens" where he entered the court of the Supreme Ruler (Heavenly Emperor), and entered the precincts of the Great Beginning. The various stops along the way, at Cinnabar Hill, Land of Deathlessness, Hot Springs of Sunrise, etc., are the meditational goalposts of his efforts at cultivating his qi and jing. The potion of the Flying Springs is his alchemical, possibly herbal, concoction of immortality; the jade was his amulet of spiritual freedom. Though he started out pallid, his complexion became radiant, and his jing (essence) was supplemented. Then his physical weight dropped away, allowing his spirit to roam free. The removal of corporeal weight is one of the signs that immortality is at hand and is mentioned frequently in the Shennong Bencao Jing as a property of herbs. Epimedium, listed in that text, was not included among the herbs that caused the body to become light, but it apparently gained a reputation as valuable for the immortals at some later date. But, even in the ancient text, it was noted the epimedium boosts the qi and strengthens the will, important contributors to the path to immortality.
Stories of the immortals date back to around 400 B.C. and continued until the 20th century, though their heyday was during the period from the Han Dynasty up to the first part of the Tang Dynasty. The early Chinese Emperors were quite interested in gaining this immortality; lacking the time and discipline to pursue the Taoist mental and physical exercises, they supported the study and development of elixirs that they could take. After the 8th Century A.D., there was more emphasis on down-to-earth practicality and only a few Taoists still spent time seeking immortality.
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Scientific References:
1.Bencao Gangmu (by Li Shizhen; 1596)
2.Narrative History and Mythology of Icariin,Chapter3,Lover and Imagination of Inter-subjectivity.
3.What is icariin or Horny Goat Weed Extract?Does Horny Goat Weed and Icariin Work for Erection?How does icariin mime testosterone?
Claims & Warning:
Claims: Information this web site presented is meant for Nutritional Benefit and as an educational starting point only, for use in maintenance and promotion good health in cooperation with a common knowledge base reference...Furthermore,it based solely on the traditional and historic use or legend of a given herb from the garden of Adonis. Although every effort has been made to ensure its accurate, please note that some info may be outdated by more recent scientific developments......
Pharmakon Warning: The order of knowledge is not the transparent order of forms and ideas,as one might be tempted retrospectively to interpret it; it is the antidote....(Dissemination,Plato's Pharmacy,II.The Ingredients:Phantasms,Festivals,and Paints;138cf. Jacques Derrida.).
And as it happens,the technique of imitation,along with the production of the simulacrum,has always been in Plato's eyes manifestly magical,thaumaturgical:......and the same things appear bent and straight to those who view them in water and out,or concave and convex,owing to similar errors of vision about colors, and there is obviously every confusion of this sort in our souls.And so scene painting (skiagraphia) in its exploitation of this weakness of four nature falls nothing short of witchcraft (thaumatopoia), and so do jugglery and many other such contrivances.(Republic X,602c-d;cf.also 607c).
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MDidea Extracts Professional
Standard Herbal Extract Series:
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Serie No.:S015.016.Basic Data Sheet Download
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seminal trace...Epimedium Extract.Horny Goat Weed Extract.Icariin.CAS.NO:489-32-7.M.F.C33H40O15.Epimedium brevicornum Maxim Extract.Icariine,Epimedium sagittatum,Epimedium Leaf Extract.Epimedium extract powder,Epimedium Alcohol Water Extract.icariin,Power of Love,Super Penis Enlarges,improves the kidney function,solves impotence and the early ejaculation,small penis,prostate diseases,sterility of long marriage,male and female frigidity,awkwardness,pains of having sex,spermatorrhoea,sore wrist and feet,poor sleep and memory,mentally depression, baldness,white hairs,middle aged and older male adults who are physically weak with a kidney dysfunction,penis shrinking and shortening,early ejaculation,scarce sexual needs etc...
Botanical info of Horny Goat Weed or Epimedium:
1. For lumbago due to kidney-deficiency, impotence and infertility due to sperm coldness, it is often used with Fructus Lycii, Radix Morindae Officinalis, Radix Rehmanniae Pareparata, Radix Acontit, etc., to tonify the kidney, strengthen yang and supplement esssence and blood.
Scientific References:
Claims & Warning:
