Magnolia officinalis,Its Bark Magnolia Cortex,Its Fragrance Components and Magnolia Alkaloids,Magnolol,Honokiol.

Contents

Common uses and Application of Magnolia Bark Extract.:

Magnolia Cortex Extract Honokiol Magnolol INCI Name MAGNOLIA BIONDII BARK EXTRACT EINECS ELINCS No 285-376-6 CAS 85085-47-8 Magnolia bark extract Officinal Magnolia Bark Extract photo picture image 1.Antioxidant and anti-stress:

 Magnolia bark has been used to treat menstrual cramps, abdominal pain, abdominal bloating and gas, nausea, and indigestion. The bark is also an ingredient in formulas used for treating coughs and asthma. The bark is used internally in the treatment of abdominal distension, loss of appetite, gastro-enteritis, vomiting, diarrhoea, asthma and coughs with acute phlegm. The bark and flower buds of Magnolia officinalis have been used to treat coughs and colds and intestinal problems.

 Researchers have determined that "honokiol" and "magnolol", two chemicals found in Magnolia Bark, are up to 1000 times more potent than Vitamin E in antioxidant activity. These two active compounds are thought to contribute to the primary anti-stress and cortisol-balancing effects of the plant. Numerous animal studies have demonstrated honokiol to act as an anti-stress agent at lower doses. Magnolol, a compound isolated from the cortex of Magnolia officinalis, has been found to possess anti-allergic and anti-asthmatic activity.

 2,Weight loss:

 Magnolia Bark is getting much press as a "cortisol", the stress hormone-lowering supplement. Cortisol has also been associated with weight gain (particularly fat in the abdominal area), sugar control problems, memory problems, and a host of other stress induced disorders.
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 3,Strong in reducing anxiety:

 In studies, honokiol was compared with diazepam (Valium), a well known pharmaceutical anxiolytic. Honokiol was found to be five times stronger than diazepam in reducing anxiety without the side effects of diazepam. While Diazepam does reduce anxiety, it also induces muscle relaxation, an effect not shared by honokiol. It would seem that honokiol is less likely than diazepam to induce physical dependence, central nervous system depression, motor nerve disruption, or amnesia at doses eliciting the anxiolytic effect. Because honokiol reduces anxiety without disruption of motor activity, it is postulated that the mechanism of the anxiolytic effect of honokiol is at least partially different from that of diazepam.

 4.Alzheimers Disease:

 Magnolia has several powerful effects on acetylcholine levels in the brain, offering potential benefits for victims of Alzheimer's Disease. Alzeimer's Disease is characterised by insufficient levels of acetylcholine, accompanied by the buildup of amyloid plaque in the brain, disrupting normal brain functioning. Two biphenolic compounds found in Magnolia, Honokiol and magnolol, increase choline acetyltransferase activity, inhibit acetylcholinesterase, promote potassium-induced acetylcholine release and exhibit neurotrophic function in in vitro studies. Choline acetyltransferase is an enzyme involved in the cellular synthesis of acetylcholine, an increase of which can up-regulate the production of acetylcholine necessary for proper brain function. Acetylcholinesterase is an enzyme that breaks down acetylcholine, the inhibition of which preserves available acetylcholine. Honokiol and Magnolol also exhibited neurotropic effects in vitro, which could translate into enhanced brain cell growth and reduced brain cell death in vivo.

 5.Asthma:

 Magnolol was found in studies to support the body's natural production of adrenal steroids (corticosteroids) which suppress inflammation. This anti-inflammatory effect is thought responsible for alleviating the allergic inflammatory response in cases of asthma. Increases in corticosteroids may be a concern for those wishing to use Magnolia as a weight loss product, but in a patented product combining the herb with Phellodendron this effect was reversed, resulting in corticosteroid reduction, and reduced cortisol-induced food cravings.
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 6. Gastric andabdominal distension of various causes:

 such as retention of dampness, stagnation of indigested food andstagnation of qi. For retention of dampness in the middle-jiao marked by abdominaldistension, nausea and vomiting, it can be dispensed with atr-actylodes and tanger-ine peel, as in Peptic Powder (Pingwei San); for stagnation of food complicated bystagnation of qimanifested as abdo-minal distension andconstipation, it can be given with rhubarb and bitter (orange,as in Decoction of Three Herbs Including Magnolia (Houpo Sanwu Tang).

 7. Cough and as-thma due to accumula-tion of phlegm in the lung:It can be used with ephedra, pinelliatuber and bitter apri-cot kernel, as in Decoction of Magnolia and Ephedra (Houpo Mahuang Tang).

 8.Traditional Applications:

 1).To treat abdominal disorders due to the obstruction of the spleen and stomach by dampness and the stagnation of qi: This herb is often used together with Chinese atractylodes rhizome (Rhizoma Atractylodis), dried tangerine peel, etc., e.g., Ping Wei San.

 2).To treat gastrointestinal food stagnancy, abdominal distention and constipation:

 a) Stagnancy and distention: This herb is often used together with immature citron or trifolia orange (Fructus Aurantii Immaturus) and rhubarb (Radix et Rhizoma Rhei), i.e., Houpu Sanwu Tang.

 b) Constipation due to heat accumulation: It is used in combination with rhubarb (Radix et Rhizoma Rhei), mirabilite and immature citron or trifolia orange (Fructus Aurantii Immaturus), i.e., Da Chengqi Tang, in order to achieve the effects of eliminating the accumulation of heat by drastic purgation and the removal of food stagnancy.

 3).To treat coughing and dyspnea (difficult or labored respiration) due to the retention of phlegm: It can be used together with cassia twig, apricot kernels, etc., e.g., Guizhi Jia Houpu Xingzi Tang.

 4).To treat coughing and dyspnea with tightness in the chest due to obstruction of phlegm and dampness in the interior: It is often used together with purple perilla seed, tangerine peel, etc., e.g., Suzi Jiangqi Tang.
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Reference:
  • Magnolia officinalis,Its Bark Magnolia Cortex,Its Fragrance Components and Magnolia Alkaloids,Magnolol,Honokiol.

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