What is Rosmarinic Acid?Super Function of RosA,Rosmarinic Acid?

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Lipoxygenase Inhibitors as Potential Cancer Chemopreventives.

Perilla Extract Perilla Ocymoides Extract EINECS ELINCS No.:290-151-0 CAS 90082-61-4 photo picture image Research and experiment proved that lipoxygenase (LO)-catalyzed products have a profound influence on the development and progression of human cancers.

 Compared with normal tissues, significantly elevated levels of LO metabolites have been found in lung, prostate, breast, colon, and skin cancer cells, as well as in cells from patients with both acute and chronic leukemias. LO-mediated products elicit diverse biological activities needed for neoplastic cell growth, influencing growth factor and transcription factor activation, oncogene induction, stimulation of tumor cell adhesion, and regulation of apoptotic cell death.

 Agents that block LO-catalyzed activity may be effective in preventing cancer by interfering with signaling events needed for tumor growth. In fact, in a few studies, LO inhibitors have prevented carcinogen-induced lung adenomas and rat mammary gland cancers.

 Rosmarinic acid,linoleic acids all good Lipoxygenase Inhibitors, and could find from perilla leaves and perilla seeds.

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citations1.What is Rosmarinic Acid?Super Function of RosA,Rosmarinic Acid?

last edit date:5th,May.2009.