Rhodiola rosea.Rosavin.Salidroside.Narrative History,Function,Uses and Application of Rhodiola rosea.Rhodiola Rosea Extract.
Article Content:
- .Basic Botanical info of Rhodiola rosea.
- .Narrative History of Rhodiola rosea.
- .Rhodiola rosea in Traditional Medicine.
- .Specific compounds set Rhodiola rosea apart from other Rhodiola species.
- .Rhodiola rosea in Modern Medicine.
- .Pharmacological and Clinical Studies of Salidroside.
- .HPLC analysis of rosavins and salidroside.
- .Phytochemistry of Rhodiola rosea.
- .Rhodiola Rosea Summary and Side Effects Note.
- .How Search engine think about Rosavin.
- .Experimental Studies and Application Study.
- .Research Update of Rhodiola rosea.Rosavin.
Phytochemistry of Rhodiola rosea.
The investigation of the phytochemistry of Rhodiola rosea root has revealed the presence of six distinct groups of chemical compounds:
Phenylpropanoids: rosavin, rosin, rosarin (specific to Rhodiola rosea);
Phenylethanol derivatives: salidroside (rhodioloside), tyrosol;
Flavanoids: rodiolin, rodionin, rodiosin, acetylrodalgin, tricin;
Monoterpernes: rosiridol, rosaridin;
Triterpenes: daucosterol, beta-sitosterol;
Phenolic acids: chlorogenic and hydroxycinnamic, gallic acids.
The standardization of Rhodiola rosea root extract has gone through two distinct p hases. Initially, in the 1970s, the compound responsible for its unique pharmacological properties was believed to be salidroside (rhodioloside).Therefore, the first generation of Rhodiola rosea tincture/extracts approved by the Russian Pharmacopoeia Committee was standardized to a minimum of 0.8 percent salidroside content.
In the late 1980s, demand for Rhodiola rosea-based phytomedicines dramatically incr eased. The wild-crafted raw material was over-harvested, resulting in a steady decline in the quality and effectiveness of "Rhodiola" preparations. Scientific investigation revealed that other species of genus Rhodiola (which also contained salidroside) were being substituted for Rhodiola rosea. While some of these mixed batches were highly variable in quality, others had no pharmacological effect. Logically, the suspicion arose that the salidroside standard was inadequate. Based on comparative analysis, the obvious hypothesis was that the original high potency product contained other active compounds specific to Rhodiola rosea that had not yet been identified.
Reference:
1.Rhodiola rosea.Rosavin.Salidroside.Narrative History,Function,Uses and Application of Rhodiola rosea.Rhodiola Rosea Extract.




