Silymarin.Milk Thistle and applications.
Contents:
- Botanical Basic Data of Milk Thistle.
- Phytochemicals of milk thistle.
- History of Silymarin and foundation.
- Modern Application and function of Silymarin and silybin.
- Dosage and Administration.
- Milk Thistle:Pharmacology.
- The Awesome Power of the Milk Thistle.
- How Search engine think about Milk Thistle.
- Research Update of Silybum Marianum.Silymarin
Applications and Properties:
Applications:
Inhibitor of Beta-glucuronidase.
Anti Free radicals.
Hepatoprotective,Liver injury protection of silymarin.
Silymarin reduced lipoperoxidative hepatic damage.
Silymarin proved against hepatotoxicity.
Promotes milk secretion,treat lactation problems,prevent cancer.
Properties:
A number of studies have suggested that silymarin is an anti-inflammatory. It regulates inflammatory mediators such as tumor necrosis factor (TNF), TNF-alpha, nitrous oxide, interleukin-, and interleukin-1 receptor antagonist. Silymarin also increases lymphocyte proliferation, interferon gamma, interleukin-, and interleukin- cytokines, in a dose-dependent manner. Taken together, these effects suggest a possible role in preventing or treating infectious disease.
Dosage: For standardized extract, 200-400 mg of silymarine per day is recommended.
Safety and Toxicity:
Acute toxicity(LD50):Silymarin.LD50-Lethal dose,50 percent kill. Intravenous.Rodent-mouse.>1600 mg/kg.Details of toxic effects not reported other than lethal dose value.
Reference:
1.Silymarin.Milk Thistle and applications.
last edit date:25th,Feb.2010.
- Name:Milk Thistle Extract
- Serie No:S-017.
- Specifications:Silymarin 80%UV.
- INCI Name:SILYBUM MARIANUM EXTRACT
- EINECS/ELINCS No.:283-298-7
- CAS:84604-20-6
- Chem/IUPAC Name:Silybum Marianum Extract is an extract of the seeds and leaves of the lady's thistle,Silybum marianum,Compositae.





