The Secret of Soy,What is Soy Isoflavones?Function of Natural Genistein?Soy Bean Extract.

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Soy Isoflavones Estrogenic and Anti-Estrogenic Activities.

Soy Bean Extract INCI Name Glycine Soja Extract Soy Isoflavones Genistein Daidzein CAS 84776-91-0 Genistein CAS 446-72-0 Daidzein CAS486-66-8 photo picture image Soy isoflavones are known to have weak estrogenic activity. Estrogens are signaling molecules that exert their effects by binding to estrogen receptors within cells (chemical structures of endogenous estrogens). The estrogen-receptor complex interacts with DNA to change the expression of estrogen-responsive genes. Estrogen receptors are present in numerous tissues other than those associated with reproduction, including bone, liver, heart and brain. Soy isoflavones and other phytoestrogens can bind to estrogen receptors, mimicking the effects of estrogen in some tissues and antagonizing (blocking) the effects of estrogen in others. Scientists are interested in the tissue-selective activities of phytoestrogens because anti-estrogenic effects in reproductive tissue could help reduce the risk of hormone associated cancers (breast, uterine and prostate), while estrogenic effects in other tissues could help maintain bone density and improve blood lipid profiles (cholesterol levels). The extent to which soy isoflavones exert estrogenic and anti-estrogenic effects in humans is currently the focus of considerable scientific research.

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citations1.The Secret of Soy,What is Soy Isoflavones?Function of Natural Genistein?Soy Bean Extract.

last edit date:6th,May.2009.