The Secret of Soy,What is Soy Isoflavones?Function of Natural Genistein?Soy Bean Extract.

article content dotArticle Content:

Soy Isoflavones Prevent Cardiovascular Disease.

Soy Bean Extract INCI Name Glycine Soja Extract Soy Isoflavones Genistein Daidzein CAS 84776-91-0 Genistein CAS 446-72-0 Daidzein CAS486-66-8 photo picture image Serum Cholesterol:

 The results of numerous controlled clinical trials in Western populations suggest that increasing soy isoflavone intake, particularly by substituting soy protein for animal protein, decreases cardiovascular risk by lowering serum total and LDL cholesterol concentrations. Substituting 25-50 g/d of soy protein for animal protein in the diet has been found to lower serum LDL-cholesterol by about 8% in adults with elevated serum cholesterol levels. There is some evidence that soy protein containing isoflavones is more effective than soy protein without isoflavones in lowering LDL cholesterol, but the consumption of soy isoflavones alone (as supplements or extracts) does not appear to be as effective in lowering serum cholesterol as intact soy protein that contains isoflavones and other phytochemicals. For more information on soy protein and cholesterol, see the article on Legumes.

 Effects on Arterial Function:

 The preservation of normal arterial function plays an important role in cardiovascular disease prevention. The ability of arteries to dilate in response to nitric oxide produced by the endothelial cells that line their inner surface (endothelium-mediated vasodilation) is compromised in people at high risk for cardiovascular disease. However, most placebo-controlled trials found no significant improvement in endothelium-mediated vasodilation when postmenopausal women were supplemented with up to 80 mg/d of soy isoflavones or up to 60 g/d of soy protein containing isoflavones. Measures of arterial stiffness assess the distensibility of arteries, and a strong association between arterial stiffness and atherosclerosis has been observed. In placebo-controlled clinical trials, supplementation of postmenopausal women with 80 mg/d of a soy isoflavone extract for 5 weeks significantly decreased arterial stiffness, as did supplementation of men and postmenopausal women with 40 g/d of soy protein providing 118 mg/d of soy isoflavones for 3 months. Although most studies have not found supplementation with soy protein or isoflavones to improve endothelium-mediated vasodilation, preliminary research suggests that soy isoflavone supplementation may decrease arterial stiffness.

Last PageNext Page

Reference:

citations1.The Secret of Soy,What is Soy Isoflavones?Function of Natural Genistein?Soy Bean Extract.

last edit date:6th,May.2009.