Ursolic acid:Actions,Commonly Known Benefit and Research.

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Actions and Chemistry of Ursolic Acid.

Loquat Leaf extract.Glossy privet leaf Extract.Ligustrum Lucidum Extract.Loquat Leaf extract.Glossy privet leaf Extract.EINECS ELINCS No.:Ursolic acid.201-034-0,CAS 223749-57-3 Ursolic acid.77-52-1.Loquat Leaf extract.Pentacyclic Triterpenes photo picture image Medicinal plants containing ursolic acid have been used in folk medicine before it was known which constituents were responsible for their therapeutic effectiveness. Contemporary scientific research which led to the isolation and identification of ursolic acid revealed and confirmed that several pharmacological effects, such as, anti-tumor, hepatoprotective, anti-inflammatory (oral and topical), anti-ulcer, antimicrobial, anti-hyperlipidemic and antiviral, can be attributed to ursolic acid.

 However, its anti-inflammatory (topical), anti-tumor (skin cancer), and antimicrobial properties are pertinent to the cosmetic industry.

 Ursolic acid has medicinally action, both topically and internally. Ursolic acid is used in many cosmetic preparations for its anti-inflammatory, antitumor and antimicrobial properties.

 Ursolic acid has antibacterial and antifungal activity. Tests have shown that Ursolic acid inhibits the growth of Candida albicans and Microsporium lenosum.
 Ursolic acid has anti-inflammatory properties and is used in ointments to treat burns.
 Topical application of ursolic acid inhibited TPA-induced initiation and promotion of tumor growth.
 Loquat Leaf extract.Glossy privet leaf Extract.Ligustrum Lucidum Extract.Loquat Leaf extract.Glossy privet leaf Extract.EINECS ELINCS No.:Ursolic acid.201-034-0,CAS 223749-57-3 Ursolic acid.77-52-1.Loquat Leaf extract.Pentacyclic Triterpenes photo picture image

 Chemistry:

 Ursolic acid [(3Beta)-3-Hydroxyurs-12-en-28-oic acid] rarely occurs without its isomer oleanolic acid [(3Beta)-3-Hydroxyolean-12-en-28-oic acid] They may occur in their free acid form, as shown in Figure 1, or as aglycones for triterpenoid saponins which are comprised of a triterpenoid aglycone linked to one or more sugar moieties. Ursolic and oleanolic acids are similar in pharmacological activity.

 Several ursolic acid derivatives, both natural and synthetic, have been reported. Novel ursolic acid derivatives, including ursane-type triterpenoid saponins, naturally occur as secondary metabolites through complex metabolic processes in different parts of the plants. Synthetic derivatives obtained from ursolic acid have been reported and evaluated for their pharmacological action

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citations1.Ursolic acid:Actions,Commonly Known Benefit and Research.

last edit date:7th,May.2009.