Ursolic acid:Actions,Commonly Known Benefit and Research.

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Safety and Toxicity for Ursolic Acid.

Loquat Leaf extract.Glossy privet leaf Extract.Ligustrum Lucidum Extract.Loquat Leaf extract.Glossy privet leaf Extract.EINECS ELINCS No.:Ursolic acid.201-034-0,CAS 223749-57-3 Ursolic acid.77-52-1.Loquat Leaf extract.Pentacyclic Triterpenes photo picture image Notwithstanding its numerous cosmetic properties, ursolic acid is an ideal cosmetic ingredient because its overall toxicity (both chronic and acute) is low. It is not a primary irritant or sensitizer. In fact, it has been termed dermatologically innocuous.

 Acute toxicity (LD50):Ursolic acid

 LD50-Lethal dose,50 percent death.Intraperitoneal.Rodent-mouse >637mg/kg.
 LD50-Lethal dose,50 percent death.Oral.Rodent-mouse.8.33grams(8330 mg)/kg.

 Chronic toxicity:Ursolic acid
 Hypodermic Injection:Rodent-mouse.3500mg/kg.No Death in 72 hours.
 Hypodermic Injection:Rodent-Rat.Dose/Period:0.5 gram/kg.30days.No distinctive effect on body weight, blood, cardiogram, liver,and kidney functions. No pathology changes for important organs,result prove ursolic acid low toxicity and safe enough.

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citations1.Ursolic acid:Actions,Commonly Known Benefit and Research.

last edit date:7th,May.2009.