Ursolic acid:Actions,Commonly Known Benefit and Research.
Contents:
- Basic Chemical Info.
- Basic Introduction and Botanical Info.
- Actions and Chemistry of Ursolic Acid.
- Commonly Known Benefit of Ursolic Acid.
- Pentacyclic Triterpenes (PCTs) as Inhibitors of Inflammation.
- Safety and Toxicity for Ursolic Acid.
- Administration and Dosage.
- Research Update of Ursolic acid.
Safety and Toxicity for Ursolic Acid.
Notwithstanding its numerous cosmetic properties, ursolic acid is an ideal cosmetic ingredient because its overall toxicity (both chronic and acute) is low. It is not a primary irritant or sensitizer. In fact, it has been termed dermatologically innocuous.
Acute toxicity (LD50):Ursolic acid
LD50-Lethal dose,50 percent death.Intraperitoneal.Rodent-mouse >637mg/kg.
LD50-Lethal dose,50 percent death.Oral.Rodent-mouse.8.33grams(8330 mg)/kg.
Chronic toxicity:Ursolic acid
Hypodermic Injection:Rodent-mouse.3500mg/kg.No Death in 72 hours.
Hypodermic Injection:Rodent-Rat.Dose/Period:0.5 gram/kg.30days.No distinctive effect on body weight, blood, cardiogram, liver,and kidney functions. No pathology changes for important organs,result prove ursolic acid low toxicity and safe enough.
Reference:
1.Ursolic acid:Actions,Commonly Known Benefit and Research.
last edit date:26th,Feb.2010.
- Name:Loquat Leaf extract.Glossy privet leaf Extract
- Serie No:S-028.
- Specifications:Ursolic acid 25%50%95%HPLC.
- INCI Name:LIGUSTRUM LUCIDUM EXTRACT
- EINECS/ELINCS No.:Ursolic acid 201-034-0
- CAS:223749-57-3,Ursolic acid 77-52-1
- Chem/IUPAC Name:Ligustrum Lucidum Extract is an extract of the berries of Ligustrum lucidum,Oleaceae





