Valeriana officinalis.Valerian and Medical Attributes.Valerian Root Extract.
Article Content:
- .Botanical Description of Valerian.Valeriana officinalis.
- .Narrative History and Ancient Register of Valerian.Valeriana officinalis.
- .Medical Attributes of Valerian.Valeriana officinalis.
- .Medical Parts,Key actions and key components of Valerian.Valeriana officinalis.
- .Valerian:Pharmacology,Mechanisms of Action
- .Traditional Uses of Valerian.Valeriana officinalis.
- .Cautions of Valerian.Valeriana officinalis.
- .Dosage of Valerian:How much to take?
- .Safety and Acute toxicity:Valerienic acid
- .Valerian and Dreams
- .Valerian,Nardostachys and Patrinia
- .Research update of Valerian Root.
Safety and Acute toxicity:Valerienic acid
Acute toxicity (LD50):Valerienic acid
LD50:Lethal dose,50 percent kill.Oral.Rodent-mouse.600mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:85GMAT "Toxicometric Parameters of Industrial Toxic chemicals Under Single Exposure,"Izmerov,N.F.,et al.,Moscow,Centre of International Projects,GKNT,1982 Volume(issue)/page/year:-,119,1982.
LD50:Lethal concentration,50 percent kill.Inhalation.Rodent-mouse.4100 mg/m3/2H.
Details of toxic effects not reported other than lethal dose value.
Reference:85GMAT "Toxicometric Parameters of Industrial Toxic chemicals Under Single Exposure,"Izmerov,N.F.,et al.,Moscow,Centre of International Projects,GKNT,1982 Volume(issue)/page/year:-,119,1982.
LD50:Lethal dose,50 percent kill.Intraperitoneal.Rodent-mouse.3590 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:JPPMAB Journal of Pharmacy and Pharmacology.(Pharmaceutical Soc.of Great Britian,1 Lambeth High St.,London SEI 7JN,UK)V.1- 1949- Volume(issue)/page/year:21,85,1969.
LD50:Lethal dose,50 percent kill.Subcutaneous.Rodent-mouse.3590 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:JPPMAB Journal of Pharmacy and Pharmacology.(Pharmaceutical Soc.of Great Britian,1 Lambeth High St.,London SEI 7JN,UK)V.1- 1949- Volume(issue)/page/year:21,85,1969.
LD50:Lethal dose,50 percent kill.Intravenous.Rodent-mouse.1290 mg/kg.
Toxic effects:
Behavioral:altered sleep time(including change in righting reflex)
Behavioral:convulsions or effect on seizure threshold.
Lungs,Thorax,or Respiration:Respiratory depression.
Reference:APTOA6 Acta Pharmacologica et Toxicologica.(Copenhagen,Denmark)V.1-59,1945-86.For publisher information,see PHTOEH Volume(issue)/page/year:18,141,1961.
NOSH data:Valerienic acid
NOHS:National Occupational Hazard Survey(1974)
NOHS Hazard Code: 84212
No. of Facilities: 21 (estimated)
No. of Industries: 1
No. of Occupations: 3
No. of Employees: 497 (estimated)
NOHS:National Occupational Hazard Survey(1983)
NOHS Hazard Code: 84212
No. of Facilities: 79 (estimated)
No. of Industries: 2
No. of Occupations: 8
No. of Employees: 4510 (estimated)
No. of Female Employees: 780 (estimated)
Reference:
1.Valeriana officinalis.Valerian and Medical Attributes.Valerian Root Extract.




