Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.

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Nettle Pharmacology:5 alpha-reductase inhibition.

Nettle Extract INCI Name Urtica Dioica Extract EINECS ELINCS No 281-685-5 CAS 84012-40-8 Urticae radix Extracts Nettle Root Extract photo picture image The enzyme 5 alpha-reductase is believed to play a role in the pathogenesis of benign prostatic hyperplasia. A 30% methanol extract of Urtica dioica roots (10:1) markedly reduced activity of 5 alpha-reductase from rats at concentrations (12mg/mL). However, in studies conducted by Rhodes et al, extract of Urtica roots (Bazoton) failed to demonstrate 5 alpha-reductase inhibition in the rat anti-androgen assay, the rat androgen receptor binding assay, and the assay for in vitro inhibition of human prostatic 5 alpha-reductase or a seven-day human clinical trial.

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citations1.Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.

last edit date:22th,May.2009.