Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.
Article Content:
- .Botanical Basic Data of Nettle.
- .Plant Description of Nettle.Urtica dioica L....Spectrology and History of Nettle.
- .Phytochemicals of Nettle.Urtica dioica L.,Urticae radix.
- .Actions and Indications of Nettle.Urtica dioica L.,Urticae radix.
- .Therapeutics and Pharmacology,Historical or traditional use of Nettle.
- .Nettle Pharmacology:5 alpha-reductase inhibition.
- .Nettle Pharmacology:Anti-inflammatory and immunomodulatory activity.
- .Nettle Pharmacology:Antiviral activity.
- .Nettle Pharmacology:Aromatase activity inhibition.
- .Nettle Pharmacology:Cell proliferation inhibition.
- .Nettle Pharmacology:Na+, K+-ATPase inhibition.
- .Nettle Pharmacology:Other activities.
- .Nettle Pharmacology:Pharmacodynamics/Kinetics.
- .Mechanism and General Use of Nettle.
- .Biological Activities and Clinical Research.
- .Dosage,Safety and Suggestions of Nettle.
- .Precautions and Possible Interactions.
- .How Search Engine think about Nettle.
- .Research Update:Nettle and Its Constituents.
Nettle Pharmacology:Anti-inflammatory and immunomodulatory activity.
The proposed use of stinging nettle in the treatment of arthritis and inflammation may be due to components found in the extract of the root. A fraction of an aqueous extract containing polysaccharides demonstrated prolonged anti-inflammatory activity in the rat paw edema test. Some of the polysaccharides isolated from this fraction stimulated T-lymphocyte proliferation or influenced the complementary system. An ethanolic extract was found to potently suppress human leukocyte elastase (HLE). HLE is one of the most destructive enzymes released by polymorphonuclear granulocytes, which migrate into tissues during the inflammatory process. The water-soluble fraction of stinging nettle leaf extract (IDS 23 - Rheuma-Hek, Germany) demonstrated a dose dependent inhibition of phytohemagglutinin stimulated production of Th1-specific interleukin 2 and interferon-( in peripheral blood mononuclear cells. In contrast, IDS 23 stimulated the production of Th2-specific interleukin 4. Inflammatory responses are primarily mediated by Th1 cells. IDS 23 has also demonstrated inhibition of leukotriene and prostaglandin syntheses, reduction of tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta) in lipopolysaccharide stimulated human whole blood and inhibition of nuclear factor (B (NF-(B). The NF-(B family of transcription factors is critical for the inducible expression of many genes involved in inflammatory responses.
Reference:
1.Nettle.Stinging nettle,Nettle leaf,Nettle root,Common Stinging Nettle?Therapeutics and Pharmacology,Historical or traditional use of Nettle.
Statistics
Spectrum
FAQ
Of Herbs