Grapefruit and GSE.Function and Application of Grapefruit seed extract.
- Botanical Basic Data of Grapefruit.
- Origin and Distribution of Grapefruit and Grapefruit Seeds?.
- Grapefruit Extract: What is GSE?.
- Production and processing of Grapefruit Extract.
- Function and Application of Grapefruit seed extracts.
- Dosage,Safety and additional comments of GSE?.
- Application of GSE in Pure Dish Wash?.
- External Application of GSE.
- Household uses of GSE.
- Function and Application GSE in slim formula.
- New, artificial grapefruit odorants.
- Frequently asked questions of GSE.
- Introduction of Naringin: Grapefruit's Fat Burning Accelerator.
- How Search Engine think about Grapefruit.
- Grapefruit Seed Extract Applications.
- Research Update:Grapefruit Seed Extract.
Function and Application of Grapefruit seed extracts.:
Grapefruit seed extracts to toothpaste may protect against viral and bacterial infections of the oral cavity, according to a report from New York City's Pace University.
The report was delivered at the 98th General Meeting of the American Society for Microbiology, held May 17-21, 1998, in Atlanta, Georgia, USA.
Over-the-counter toothpastes and mouth rinses may kill bad breath and bacteria, but most are virtually harmless against viruses. In this study researcher Milton Schiffenbauer and colleagues \ added zinc, aloe, or grapefruit seed extract to mouthwashes, rinses, and toothpaste in an effort to prevent disease-causing microorganisms in the mouth.
Medical researchers have recently discovered that bacterial infections in the mouth may lead to blood clots that can bring on heart attacks and strokes. The article also noted that several studies conducted since 1989 suggest that people with periodontal disease also have an increased risk of heart disease and stroke.
For the past several years, scientists in Pace University's Biology Department have conducted research on oral microbiology and viruses. Their studies found that most of a variety of oral \ agents tested for their antiviral properties were not effective, and some even protected viruses under certain conditions.
Their research focused on two viruses(bacteriophages T1 and T7, which infect Excheria coli B) that attack bacteria. Extracts of zinc, aloe, and grapefruit were separately added to toothpaste and combined in test tubes with the viruses. The loss of phage titer, as a result of these natural additives, was observed for phage stored at room temperature(25 degrees C.), at refrigeration(4 degrees C.) and at subfreezing (-12 degrees C.) temperatures.
T1 and T7 were totally inactivated after 10 minutes exposure at room temperature to NutriBiotic brand grapefruit seed extract(undiluted and 10% dilution). An appreciable decrease in T1 titer, i.e. 85% loss, was also obtained with a crude extract of grapefruit peelings.
Zinc totally inactivated both phages. T1 inactivation occurred after 10 minutes mixing at room temperature, whereas T7 inactivation occurred after one day storage under refrigeration.
Tom's of Maine toothpaste had no antiviral effect on T1 or T7 and actually protected the phages from inactivation at sub-freezing terperatures. However, in the presence of 1% zinc, the toothpaste had a very significant antiviral effect on both phages; total inactivation occurred after one day storage under refrigeration.
Substantial inactivation of both phages was obtained with purified aloe vera after two days of storage(day one under refrigeration, day two at subfreezing temperature), i.e. 88% and 95% loss of titer for T1 and T7, respectively.
A crude extract of aloe, strained or unstrained, had little, if any, effect on the phages. Tom's of Maine mouthwash which contains purified aloe vera juice totally inactivated T1 and T7 after 10 minutes of mixing at room temperature. After 10 minutes of storage at room temperature, under refrigeration and in sub-freezing conditions, T1 and T7 viruses were virtually inactivated.
"This research serves as a model to investigate viral and bacterial infections of the oral cavity," Schiffenbauer said. "Pace researchers will expand their study to include other common forms of viruses that may weaken the gums and allow entry of harmful bacteria."
The corresponding author for this study is Milton Schiffenbauer, Pace University Biology Department, 1 Pace Plaza, New York, NY 10038.
Grapefruit extract is also effective in treating thrush, an oral infection of candida yeast. Thrush can be remarkably resistant to many therapies, but excellent results have been obtained with GSE.
Grapefruit Extract effective against anthrax:
No specific anthrax testing has been done, as far as we know. GSE is likely an effective treatment for anthrax, and possibly smallpox and other biological weapons, but we may never know for sure. GSE destroys bacillus subtilis, a spore that causes food spoilage and is a cousin of the anthrax spore, bacillus anthracis. Laboratory tests required only 2 ppm concentration to inhibit B. subtilis.
Serious efforts have been made for years to get the F.D.A. to evaluate GSE(E.P.A. has been petitioned also). Both agencies have consistently ignored the petitions. This is most unfortunate, as there are literally thousands of people who can testify to the effectiveness of GSE against dozens of harmful pathogens, including some very dangerous drug-resistant strains.
GSE damage intestinal flora?
The answer is a qualified no. Even though we don't have clinical studies to prove it, all the feedback from consumers, doctors, veterinarians and others is to the effect that GSE does not damage the beneficial bacteria in the digestive tract at normal doses. We are also highly in favor of supplementation with acidophilous and other so-called probiotics.
Can Germs Become Resistant to GSE as they can to antibiotics?
There is no evidence that any type of micro-organism has ever developed a resistance to Citricidal or Nutribiotic grapefruit extracts. In fact it is believed that such resistance is not possible because of GSE's mode of activity. Because GSE actually disrupts the cytoplasmic membrane, changes in genetic make-up in the pathogenic organism would be irrelevant. What is still not known is how GSE can be effective against viruses, inasmuch as a virus has no cell membrane of its own.
What about rumours of Chemicals in GSE?
Newsgroups and email groups have received postings to the effect that GSE contains Triclosan, Benzelthonium Chloride, or Methyl Paraben. The source of this type of report comes from both Germany(Here is the PubMed reference to the German Report) , where Citricidal is not approved for human consumption. A more recent attack on GSE can be found at this link. The reason is that Citricidal is very similar in molecular weight to both Benzelthonium Chloride and Triclosan, both of which are effective disinfectants, but are toxic to human and animal life. In Germany their test for BC, Triclosan, and M.Paraben comes up positive(which is more correctly called a "false positive") and in China, the same is happening for Triclosan. USDA found benzelthonium chloride in its 2001 test. Was this a simple error or a deliberate attempt to scare people away from Citricidal and Nutribiotic products?
Meanwhile, Citricidal has been tested for the presence of these toxins by independent labs, and has been proven clean. (Ex: Weston Gulf Coast Laboratories, Inc., University Park, IL, test completed in March of 1992. Tested for heavy metals, Cyanides, Pesticides and PCBs and Benzelkonium Chloride. Results: None Detected.) In fact, the accusations about triclosan(used in many dish and hand soaps in the US) became so frequent a few years ago, that Citricidal began specifically testing each batch of GSE for its absense, and providing a Certificate of Analysis to that effect.
The truth is, Citricidal is not only effective, it has been in use for many years. If these allegations had any validity, there certainly would be a history of complaints and judgements against the product, and it would have been removed from the market many years ago. Triclosan has recently been compared to "Agent Orange" in toxicity. The EPA rates triclosan as "highly toxic". The US FDA made inspections of the Nutribiotic manufacturing facility back in the 1990's and found no chemical preservatives; and the formula is the same today.
Such rumours are false, and are not a threat to those armed with accurate information. The test reports from Germany and the USDA are certainly bothersome, but they have produced "false positives", not accurate profiles. The vast body of evidence from many years of use by thousands of satisfied consumers, doctors, manufacturers, and veterinarians, speaks most loudly against such reports. (The German report, linked above, does suggest that some suppliers of "GSE" may, in fact, be fraudulent. But Citricidal and NutriBiotic GSE are both proven, safe, and effective products.)
- 1.Grapefruit and GSE.Function and Application of Grapefruit seed extract.
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