Cuscuta chinensis.Dodder.Dodder seed extract Pharmacological Actions.

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Polysaccharide of Cuscuta Chinesis and its Immunological Adjuvant Effect.

Dodder Seed Extract Cuscuta chinensis Extract photo picture image The result indicated that the hot water extract of seeds of Cuscuta chinensis Lam. is able to elicit specific antibody against synthetic peptide or tumor-associated carbohydrate antigens that may has potential as an adjuvant for therapeutic vaccines.

 Immunotherapy of human cancer based on peptide as well as carbohydrate tumor-associated antigens is a rapidly growing experimental area.

 Both synthetic peptides and carbohydrate tumor-associated antigens are poor immunogenic substances which are very difficult to elicit specific antibody against peptide or carbohydrate antigens without adjuvant help. A great need thus exists for safe and effective adjuvants.

 The hot water extracts were prepared from 13 Chinese herbs, and the polysaccharides were precipitated with ethanol. The polysaccharides were mixed with synthetic peptide or tumor-associated carbohydrate antigens and used for immunizing Balb/c mice and the serum titer were monitored every week.

 Immunotherapy of human cancer based on peptide as well as carbohydrate tumor-associated antigens is a rapidly growing experimental area.

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citations1.Cuscuta chinensis.Dodder.Dodder seed extract Pharmacological Actions.

last edit date:19th,May.2009.