Hoodia kills the appetite and attacks obesity, is organic with no synthetic or artificial appetite control agents, has no known side effects, contains a miracle molecule (up to 100000 times more powerful than glucose) that fools the brain into believing you are full, and even stops you from thinking about food. But it actually does MORE...
It gives you the freedom and control you've always wanted. It allows you to lose weight in the knowledge and comfort that you'll never miss out on a luncheon, dinner, or festive occasion again for fear of overeating.Hoodia Cactus contains a molecule that is estimated to be up to 100000 times as potent as glucose in sending a signal to the brain that the body is in a state of satiety, or in common terms not hungry.
Hoodia is a plant belong to the Trichocaulon order of Asclepiadaceae(Asclepiadeae) family,A small genus (two species) of dwarf-growing succulents, natives of South Africa. Genus Hoodia is selected from the species Hoodia gordonii,Hoodia curroii,Hoodia lugardii, Hoodia macrantha, Hoodia ruschii,Hoodia currari and several others,How to bet or guess which Hoodia of Trichocaulon contains P-57?
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Basic Instruction
Hoodia.the Succulent Asclepiad Trichocaulon.Natural Arid Hoodia Plus Sense Thirst.How the Hoodia Appetite Suppressant Steroidal Glycoside work?
Botanical Basic Data of hoodia:Natural Arid Hoodia,Miracle Cactus
Botanical Source:Succulent Asclepiad Trichocaulon Hoodia Gordonii,
Scientific Name: Hoodia gordonii Sweet
Common Names:Hoodia(Who Dee a),Miracle Cactus
Synonym: Hoodia Cactus Gordonii,Hoodia Gordonii,the Carrion Flower (Hoodia)
Part Used:plant material such as the core part of stems and roots of Hoodia Gordonii cactus,The P57 molecule was extracted from the heart of Hoodia Gordonii,- not the skin.
Genus Hoodia is selected from the species Hoodia gordonii,Hoodia curroii,Hoodia lugardii, Hoodia macrantha, Hoodia ruschii,Hoodia currari and several others
Order: Trichocaulon
Note of Trichocaulon:from thrix, trichos, a hair, and caulon, a stem; alluding to the bristles that tip each tubercle. Hoodia spp. belong to the Trichocaulon Subgroup of Succulent Asclepiad Genera.
Family: Asclepiadaceae(Asclepiadeae)
Recommended Temperature Zone:USDA: 10-11
Frost Tolerance: Hardy to 28oF ( -2oC)
Sun Exposure: Light shade, morning sun
Origin: Southwestern Africa,East Part of South America, some other desert living circumstance, or exactly, it is the succulent plants growing in arid regions.
Growth Habits: Succulent, forming clumps of 12 inches tall, 12 inches wide (30 by 30 cm); mature in 5 years or longer.Commercially planted Hoodia Gordonii herb normally cutted to use when grow to about 2 inches around.
Propagation: Cuttings
Hoodia is a succulent in the family Asclepiadaceae. It forms multi-stemmed clumps 45cm (18in) high and bears unpleasant-smelling, pale purple disc-shaped flowers 7.5-10cm (3-4in) in diameter.First found in semi-arid areas of South Africa. The San people, formerly known as bushmen, of the Kalahari eat the bitter-tasting plant to suppress their appetite and thirst when on long hunting expeditions.
Hoodia gordonii looks very much like a columnar cactus. It is not a very common plant and it grows in the semi-deserts of Zambia, Zimbabwe, Botswana, Namibia, Angola and Republic of South Africa.. It grows rather slow - it takes about 5 years of growing it, before it flowers and before you can start harvesting any of it. It can be 15 - 20 years before the plant is fully grown and at the peak of its productive life.
What is hoodia(Hoodia Gordonii Cactus) and Hoodia Extract?:
An Internet search for "Hoodia", "Xhoba" (the name given the cactus by the San Bushmen) and "Hoodia Extracts" (so named because it was the Extracts or powdered extract of Hoodia) turns up some very interesting information.
Hoodia is a plant belong to the Trichocaulon order of Asclepiadaceae(Asclepiadeae) family,A small genus (two species) of dwarf-growing succulents, natives of South Africa. Flowers small, proceeding from the angles near the upper part of the stem, sub-solitary; calyx five-partite, the segments acuminate; corolla deeply five-lobed; outer corona deeply bilobed. Leaves none. Stems dwarf, stout, fleshy, many-angled; angles tuberculate; tubercles tipped with a bristle.
If you look at the picture on our site of the Hoodia in Bloom you will see pink flowers on the tops. They smell like dead animals so they attract flies and that is how they germinate. The part of the hoodia plant that we use is the stem that comes up from the ground and the root is left in to regrow.
Hoodia cacti discovered first in the semi-deserts of South Africa, Botswana, Namibia and Angola. There are about 20 species in this family but the cactus gordonii is the one that contains a natural appetite suppressant.
Hoodia is a bitter-tasting cactus-like plant. The full name is Hoodia Gordonii. Hoodia is a Succulent botanical which resembles a "cactus". For this reason, hoodia is often mistaken called the "african hoodia cactus". If you must know all the technical data it is Genus: Trichocaulon and Family Name: Asclepiadaceae. Full grown Hoodia plants can grow over 6 feet tall.
But using modern farming methods (use every means to make it look a picture of perfect health, make it taste good, and accelerate physical growth to maximum, regardless of nutritional qualities) the first harvest is possible at the age of four years and now cultivated large scale and big quantity at Farm land of SA and other Areas of Africa,some other arid regions of South America Nations such as Chile,Peru and some arid regions of West China.
Extract contain concentrated amounts of the active ingredients found in nature,The 20:1 extract in Hoodia is twenty times as potent in active constituents as the hoodia plant itself.
Extract from this succulent have shown in clinical trials on obese subjects to reduce caloric intake by 30% to 40%. Significant weight loss has resulted from such a drop in caloric intake.
Some tech data basic of hoodia extracts:
Extract method:Hydro-alcoholic (Ethanol&Water);Appearance:Light yellow fine brown powder.
The Hoodia plant literature:
Hoodia is a genus in the Asclepiadaceae family.There are approximately 20 species in the genus. The unusual flowers are flat and saucer-like in shape and red, purple to brown or mottled dark yellow in colour. Flowers form prolifically near the stem tips in summer. The short stems are many angled with white spikes appearing at short intervals on each angle. Stems are single or branch forming, they occur in variable shades of green. Plants are found in a large part of Southern Africa, also other desert living circumstance.
Deep inside the African Kalahari desert, grows an ugly cactus called the Hoodia. It thrives in extremely high temperatures, and takes years to mature.
The Hoodia gordonii has become lately in the spot light of a public interest as a supplement for diet by suppressing hunger and thirst.
Since time immemorial, the succulent Hoodia has grown in the Kalahari desert in southern Africa and has been eaten by the San bushmen during their long hunting trips. Its juice takes the edge off appetite and thirst, and has enabled the hunters to respect their tradition of bringing home their entire catch, without eating of it on the way.
The San Bushmen of the Kalahari, one of the world's oldest and most primitive tribes, had been eating the Hoodia for thousands of years, to stave off hunger during there trips they cut off a stem of the Hoodia cactus about the size of a cucumber and munch on it over a couple of days.
The Haioms of northern Namibia still use Hoodia sap to treat allergic reactions in the eyes, and to treat severe stomach pain they boil Hoodia pieces in water and drink the brew. The Anikhwe of northern Botswana feed children who "eat too much" pieces of Hoodia to make them eat less. Already decades ago obese members of the Khomani community of north-western South Africa were eating the Hoodia to slim down or to maintain a high energy level.
In the old days people consumed the plant to meet the requirements of a healthy body whereas today overweight young people do so to slim down to meet the requirements of fashion. Now the Hoodia, which grows to 6ft - taller than the bushmen themselves - is in the centre of public interest the cactus also attracted the interest of the Western drug industry.
Cultivating these slow growing plants can be difficult, they need temperatures of at least 10 -16 oC (50-61 F) in sun or shade. There are about 20 species in this family. The plant form a clump of short, upright stem in pale green.
The History of Hoodia Discovery:
Hoodia is an ugly cactus that first discovered the African Kalahari desert. It thrives in extremely high temperatures, and takes years to mature. Kalahari natives been eating the Hoodia for thousands of years, to stave off hunger during long hunting trips. Scientists using extracts of Hoodia believe they can manufacture an organic diet pill that reduces appetite and attacks obesity. Because Hoodia has no known side-effects, and contains a powerful molecule that fools your brain into believing you are full, experts consider that, when properly developed and tested, Hoodia weight loss pills may be a solution to the obesity epidemic.
In 1937, a Dutch anthropologist studying the San indigenous people in the Kalahari desert near what is now the South Africa-Namibia border noted that they sucked on the Hoodia plant as an appetite suppressant and thirst quencher.
These bushmen did not eat on their two to three day hunts; instead, they munched on the stem of this succulent to suppress their hunger and thirst. The San people, known for their survival skills, rock art, trance-dancing and mystic symbiosis with their semi-desert or savannah environment, can trace their heritage back some 27,000 years on the basis of rock paintings drawn by their ancestors.
The reason it has taken so long to bring this natural compound to the marketplace has to do with modern research methodology since the effects were first observed in 1937 by a Dutch anthropologist studying the San Bushman of the Kalahari Desert. He noticed that they munched on the stem of a certain variety of Hoodia plant as an appetite suppressant and thirst quencher before and during nomadic hunts through the sandswept and sparsely vegetated area.
Interestingly, the San, who can trace their heritage back 27,000 years based on rock paintings, are one of the world's oldest and most primitive tribes. They have known about the properties of Xhoba for thousands of years.
Besides alleviating hunger and thirst, Xhoba also provides a state of alertness but without the jittery feeling produced by the current Western diet remedy of ephedra stacked with caffeine. Thus it is an ideal choice for days' long hunts where prey is tracked over hundreds of miles.
Hoodia sat on the back shelf in a lab for almost another thirty years when South African scientists at the Council for Scientific and Industrial Research (CSIR) began studying it. Lab animals fed the flesh of the cactus lost weight, but otherwise suffered no ill effects.
Why we need Hoodia?
One Fact: Obesity is a growing problem in Western countries, where 100 million people are dangerously overweight.
Doctors say excessive weight gain causes a myriad of medical problems including heart disease, diabetes, cancer and the onset of strokes.
The truth about food after 40 is that it is required for maintenance only. We really don't need to eat that much to keep healthy, trim and fit. The problem is we live in a culture that forces food at us.
In America the tendency is to snack all day. For many of us there are no meal times. We sneak down to the fridge at two in the morning and hit the HaagenDaz, consume huge amounts of calories and still not feel full. We think too much about food, make too many ceremonies around it. But how can we stop?
The miracle of hoodia is that it's able to do it for you:
Hoodia extracts gives you the freedom and control you've always wanted. It allows you to lose weight in the knowledge and comfort that you'll never miss out on a luncheon, dinner, or festive occasion again for fear of overeating.
Mechanism of hoodia extract work? :
Hoodia Contains Steroidal glycosides:
When scientists were routinely testing Hoodia, they discovered that Hoodia contains a previously unknown molecule, which has since been identified as Steroidal glycosides.
Whole hoodia powder contains variable amounts of fiber, organic material, antioxidants and biologically active substances including steroidal glycosides, which appear to fool the brain into thinking the stomach is full.
Chemical Name: Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O- methyl-Beta-D-ribo-hexopyranosyl)oxy]- 14-hydroxy- 12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn- 5-en-20-one.
Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O- methyl-Beta-D-ribo-hexopyranosyl)oxy]- 14-hydroxy- 12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn- 5-en-20-one.
(3Beta,12Beta,14Beta)-3-[(O-6-Deoxy-3-O-methyl-Beta-D-glucopyranosyl-(1->4)-O-2,6-dideoxy-3-O-methyl-Beta-D-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-Beta-D-ribo-hexopyranosyl)oxy]-14-hydroxy-12-[[(2E)-2-methyl-1-oxo-2-butenyl]oxy]pregn-5-en-20-one
Other names: P57;P57AS3.
Chemical formula: C47H74O15Molecular mass: 879.08 g/mol CAS No: 384329-61-7
How Hoodia Steroidal glycosides Helps to Reduce Weight
There is a part of your brain, the hypothalamus. Within that mid-brain there are nerve cells that sense glucose sugar. When you eat, blood sugar goes up and these nerve cells signal that you are full. The Hoodia Steroidal Glycosides is about 10,000 times as active as glucose. It goes to the mid-brain and actually makes those nerve cells react as if you were full. But you have not eaten. Nor do you want to.
Hoodia Steroidal glycosides works by mimicking the effect that glucose has on nerve cells in the brain : in effect fooling the body into thinking it is full, even when it is not, thus curbing the appetite.
The irony that some of the world's most overfed people may benefit from some of the hungriest was not lost on the San.
"At first people here were a bit shocked," said Nigel Crawhall, a professor at the South African San Institute and a campaigner for the rights of indigenous tribes. "Why would anybody want to lose weight by eating the hoodia plant? Because it's meant for when you're traveling across the desert and you don't have enough to eat. So we thought it was a bit weird."
hoodia extracts kills the appetite and attacks obesity, is organic with no synthetic or artificial appetite control agents, has no known side effects, contains a miracle molecule (up to 100000 times more powerful than glucose) that fools the brain into believing you are full, and even stops you from thinking about food. But it actually does MORE...
Since Hoodia Contains a powerful molecule that fools your brain into believing you are full, experts consider that, when properly developed and tested, Hoodia weight loss formula may be a solution to the obesity epidemic.
Most human users claim that it produces an immediate effect upon eating - an upliftment in mood immediately, followed by a complete satiation of the appetite. After eating Hoodia one simply doesn't feel like eating a thing. You might want to eat because you know its lunchtime, but there's simply no desire to chew and swallow your food.
According to some users of fresh Hoodia it is a wonderful plant to eat. They say it tastes sweet and bitter, but others say the taste needs to be improved to be as edible to humans as cucumbers.Though clinical trials on aphrodisiac qualities of the plant have not been conducted, the reports and testimonials of users are very persistent. Besides alleviating hunger and thirst, Hoodia also provides a state of alertness but without the jittery feeling produced by the current Western diet remedy of ephedra stacked with caffeine and aspirin. Thus it is an ideal choice for days' long hunts where prey is tracked over endless miles and there is no food available. It is equally useful for people in urban and western societies, when people are either bored or stressed and overeat to ease the boredom or the stress.
The steroidal glycosides that help Hoodia gordonii to survive by curbing the appetite of grazers, will have to be present in Hoodia macrantha and ruschii and currari and several others - where the species differ just by the average height, or how many ribs they have, or the color of the flowers. According to one contributor to a gardening forum, Hoodia macrantha cannot be distinguished from Hoodia gordonii until the plants are some 5 years old and they start to flower.
Clinical Diet and Weight Loss Trials of Hoodia
The first animal trials for Hoodia were on rats. Rats will eat literally anything. But after being given Hoodia they stopped eating completely. When the first human clinical trial was conducted, a morbidly obese group of people were placed in a "phase 1 unit", a place like a prison. All the volunteers could do all day was read papers, watch television, and eat. Half were given Hoodia, half placebo. Fifteen days later, the Hoodia group had reduced their calorie intake by 1000 a day. These remarkable weight control results are the reason why scientists see Hoodia weight loss pills as a potential answer to obesity and severe overweight.
Hoodia Gordonii Cactus and Hoodia Extract, the new weight loss miracle?. and More...
Currently there is a major breakthrough on the weight loss front as South African researchers did research on the food eaten by the San people.
They discovered they did eat parts of the Hoodia cactus to suppress their appetite during hunting trips.
We consider Hoodia Gordonii Cactus to be the answer to obesity in western civilization, after eating Hoodia you just don't think about food. We put small doses into our products just to reduce your appetite, as Hoodia is so powerful eating too much and going without food for days can be harmful, the San tribesmen can do this as they have practiced this for generations.
When you consider the recent government reports on obesity then what better product can there be to reduce this plague in western society. We foresee that in the future there will be thousands of Hoodia products available and it will overtake Natural Hoodia Pluse Sense Thirst as the next diet phenomena.
Steroidal glycosides is an appetite suppressant with novel pharmacological properties that has no effects on behavior. It is extracted from the Hoodia cactus, a dwarf-growing succulents plant which has been eaten by Bushmen for thousands of years to stave off thirst and hunger during long hunting trips.
Hoodia Diet and formulas are made from Gordonii Cactus Plant extracts and are the result of years of scientific research. Hoodia had its native origin in South Africa where it was noticed that Indigenous people were using this plant to both quench their thirst and as an appetite suppressor. Only when clinical trials confirmed the effectiveness of gordonii cactus plant extract, was it made available as a dietary weight loss product.
Some Hoodia formula have been supplemented with calcium pyruvate to enhance weight loss through fat reduction and chromium to help regulate blood sugar levels.
Effects of Hoodia and clinical trial and values of hoodia.
According to Dixey, the hypothalamus is the organ affected by the Steroidal glycosides molecule because it's the location of the "nerve cells that sense glucose sugar. . . .When you eat, blood sugar goes up because of the food, [and] these cells start firing [so you feel full]. What the Hoodia seems to contain is a molecule that is about 10,000 times as active as glucose. It goes to the [hypothalamus] and actually makes those nerve cells fire as if you were full. But you have not eaten. Nor do you want to."
From the first animal trials, choosing rats because they are "creatures who will eat literally anything." When fed the cactus, they stopped eating completely.
When the first human clinical trial was conducted, a morbidly obese group of volunteers were placed in a Phase 1 Unit. In this controlled environment, where subjects were literally incarcerated, all they did was read, watch television, and eat. Half were given Hoodia and the other half, a placebo. Fifteen days later the Hoodia group had reduced their caloric intake by 1000 a day and suffered no ill effects. The stuff clearly seemed to work as shown by the following graph.
The truth about food after 40 is that it is required for maintenance only. We really don't need to eat that much to keep healthy, trim and fit. The problem is we live in a culture that forces food at us. In all late modern big cities the tendency is to snack all day. For many of us there are no meal times. We sneak down to the fridge at two in the morning and hit the HaagenDaz, consume huge amounts of calories and still not feel full. We think too much about food, make too many ceremonies around it. But how can we stop?
The miracle of Hoodia is that it's able to do it for you,experience with hoodia:
In addition to my skepticism about the studies conducted on hoodia so far, my own experience with hoodia uncovers some additional questions. Naturally, I tested hoodia on myself for quite some time. During that time, I carefully noted my level of hunger three times a day (rating my appetite on a scale of 2 - 10), and noted my dosage of hoodia gordonii. Here's what I learned:
Hoodia does help suppress your appetite, but there are many caveats.
The dosage of hoodia necessary to truly suppress my appetite was far, far larger than the dosages claimed by many websites selling hoodia. While some hoodia formulas contain only 100mg of hoodia per serving, I found that I needed 500mg of hoodia three times a day to have any real effect. That's 1.5 grams of hoodia per day.
Hoodia does not counteract the blood sugar drops that occur following the consumption of refined carbohydrates like soft drinks, cookies, white bread, white rice and other simple carbohydrates. In fact, on days that I ate carbs, my appetite wasn't lowered at all. Hoodia only appeared to work in conjunction with a controlled carbohydrate diet. And some would say that a controlled carb diet works by itself anyway (which is partly true, but in my case, I also have to give some credit to the hoodia).
Hoodia in no way stops your body from feeling intense hunger after a heavy workout. When I engage in strength training, I feel ravenous within minutes. Of course, I train harder than 99% of the people out there, but let this be a lesson: if you work out hard, you're still going to feel hungry, hoodia or not. In other words, hoodia doesn't cause your body to lose its mind. Your muscles still scream out for calories.
The best form of hoodia was the powder extracts. Turns off the hunger more rapidly (which requires slow digestion to extract the chemical compounds).
Hoodia Drive Out Obesity.
The "Eat less and exercise more" recommendation is much too simplified solution to obesity. There are dozens and dozens reasons for the epidemic of obesity. One could almost say there are as many reasons as there are fat people. In scientific terms, obesity occurs when a person consumes more calories than he or she burns. Causes of this imbalance will differ from one person to another.
The major causes of Obesity are following:
- Nutritional quality of the foods consumed,
- Environmental and social factors: eating habits, levels of activity, choices of food
- Metabolism of an individual
- Food and environmental allergies and sensitivities, prescription drug use,
- Psychological factors, such as stress, emotions, boredom, sadness, anxiety, or anger
- Genetic, though this is believed to be the cause in less than 10% of overweight individuals
- Some illnesses: Cushing's syndrome, depression, hypothyroidism, organ disease, blood sugar imbalance, essential fatty acid deficiency, and certain neurological problems.
We are told all the time - a balanced diet will provide your body with all the nutrients it needs for good health, but in recent years first cracks started to show in official reports, though VERY cautious, such as: It appears that the mass produced foods we eat may have low levels of certain nutrients. We may have to consume greater quantities of foods (and calories) to meet the requirement of our bodies.
This can explain why the general health of somewhat overweight individuals is sometime better than health of many slim people. Most diets will direct you to reduce the quantity of food you consume and do aerobics, or go jogging, or vigorous physical exercises. If you will follow that kind of program, by reducing the quantity of the food you eat, you will further reduce the intake of the micro nutrients that your body craves for. The craving will be even worse. Taking appetite suppressants will help in some cases, but in most cases the cause of the increased appetite is not solved - the appetite suppressants won't supply you with the micro nutrients that your body craves.
A technical, encyclopedic definition of starvation: Starvation is classified into three categories based on caloric intake over time (Frisancho, 1981):
1. Acute - less than 600 calories/day for less than two weeks.
2. Semi acute starvation - less than 1100 calories/day for less than 30 days.
3. Moderate semi starvation - less than 1600 calories/day for as long as 24 weeks.
This is where Hoodia comes in so handy. It is not terribly difficult to design a diet that has 100% of the nutrients, but only 60% of the calories that you need, especially if you use such nutrients dense foods as spirulina, nuts, some supplements, vitamins and minerals. (There are some fantastic computer programs to help you with the selection of the foods.) Hoodia will suppress the hunger feelings and you will function normally.
Where to Souce Hoodia Gordonii Cactus Extract?.
Powder processing of Hoodia Gordoni Cactus Extracts:
MDidea Group confirm developed special method to make extracts from the genus Hoodia and process deliver Hoodia Gordonii extracts bulk and solely control the commercially production quantity and market policy.
The succulent plants growing in arid regions ground dried and milled, leaving only 5% of its original weight, this fine powder appeared its special light pale yellow and light smells.Extracts from this succulent have shown in clinical trials on obese subjects to reduce caloric intake by 30% to 40%. Significant weight loss has resulted from such a drop in caloric intake.
Method brief as following:Preparing an extract of a plant of the genus Hoodia, the extract comprising an appetite suppressant agent, the process including the steps of treating collected plant material with a solvent to extract a fraction having appetite suppressant activity, separating the extraction solution from the rest of the plant material, removing the solvent from the extraction solution and recovering the extract. The extract so recovered may be further purified, eg by way of suitable solvent extraction procedures.
Extracts contain concentrated amounts of the active ingredients found in nature.The 20:1 extract in Hoodia is twenty times as potent in active constituents as the hoodia plant itself. Whole hoodia powder contains variable amounts of fiber, organic material, antioxidants and biologically active substances including steroidal glycosides.
Research from MDidea Group found that the aqueous ethanolic extract from the fresh stems of Hoodia Cactus showed potent radical scanvenging activity. Some new compounds, opuntioside I, 4-ethoxyl-6-hydroxymethyl-alpha-pyrone, and kaempferol 7-O-beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranoside, were isolated from the extract.
Also an important phytochemical identified: 3-0-[-.beta.-D-thevetopyranosyl-(1.fwdarw.4)-.beta.-D-cymaropyranosyl-(1.f wdarw. 4)-.beta.-D-cymaropyranosyl]-12.beta.-0-tigloyloxy-14-hydroxy-14.beta.-pre gn-50-en-20-one
The structures of the new compounds were determined on the basis of chemical and physicochemical evidence and the radical scavenging effects of principal constituents were examined.
Hoodia Gordonii:Scientific Support..
Studies of the anorectic mechanism of Hoodia Steroidal Glycoside.:
A Steroidal Glycoside with anorectic activity in animals was isolated from Hoodia gordonii and found to have homologies to the steroidal core of cardiac glycosides.
Intracerebroventricular injections of Steroidal Glycoside demonstrated that the compound has a likely central mechanism of action. There is no evidence of Steroidal Glycoside binding to or altering activity of known receptors or proteins, including Na/K-ATPase, the putative target of cardiac glycosides.
The studies demonstrated that the compound increases the content of ATP by 50-150% in hypothalamic neurons. In addition, third ventricle administration of Steroidal Glycoside, which reduces subsequent 24-h food intake by 40-60%, also increases ATP content in hypothalamic slice punches removed at 24 h following the injections.
In related studies, in pair fed mice fed a low calorie diet for 10 days, the content of ATP in the hypothalami of control i.c.v. injected animals fell by 35-45%, which was blocked by i.c.v. injections of Steroidal Glycoside.
With growing evidence of metabolic or nutrient-sensing by the hypothalamus, ATP may be a common currency of energy sensing, which in turn may trigger the appropriate neural, endocrine and appetitive responses as similar to other fundamental hypothalamic homeostatic centers for temperature and osmolarity.
These research of the anorectic mechanism of hoodia steroidal glycoside guided by scientists of MDidea Group proved that Increased ATP content & production in the hypothalamus may be a signal for energy-sensing of satiety.
Weight control is all about calorie control. Recent scientific studies have confirmed the ability of hoodia to suppress appetite, helping obese people and free-feeding rats lower dietary calorie intake to a degree that promotes weight loss, at least in the short term.
Controlled clinical and laboratory experiments show both animals and humans will restrict the calorie intake in their diet when hoodia is taken orally. Some experiments have involved elaborate studies where obese people have taken hoodia in a controlled metabolic environment; and they have been able to reduce their calorie intake by 1,000 calories per day.
Benefit of Hoodia Gordonii Cactus and Hoodia Extract?:
Appetite decrease and energy increase: Increase your energy by removing toxins that wear you down.
Hoodia is a new, exciting and powerful nutritional supplement that will supress your appetite like no other product.
Hoodia Cactus is not really new, it has been used by the indigenous tribal people in South Africa as a natural appetite suppresant and thirst quencher during long hunting trips for generations.
Used for hundreds of years by African tribes when hunting for many days, this plant extract stops the hunger feeling, allowing the hunters to last many days without eating while collecting food for the family. This unique natural cactus extract will not only stop your hunger, it also makes you feel good, removing the normal tiredness and weakness feeling you get when not eating.!
Consume Calories: basic function of the Hoodia Gordonii Cactus
Hoodia Cactus contains a molecule that is estimated to be up to 100000 times as potent as glucose in sending a signal to the brain that the body is in a state of satiety, or in common terms not hungry.
In clinical tests, rats which normally eat everything given them, stopped eating when fed hoodia cactus. In humans, two groups were given equal diets and placed in a setting where there was nothing to do but sit, eat, read or watch the TV. One group was given hoodia and the other a placebo. The hoodia group consumed on average 1000 calories a day less than the placebo group.
The rediscovered extract from this cactus has been tested in clinical trials and discovered on obese subjects to reduce caloric intake by 40% to 50%.In effect telling us we're full, even when we are not, thus curbing the appetite....And some of benefit of the hoodia extracts briefly listed following:
*End your cravings for habit-forming substances such as sugar, caffeine, nicotine, alcohol, and drugs.
*Shrink your stomach to its normal size, making it easier to control the quantity of food eaten.
*Boost your mental clarity by flushing away chemicals, food additives and preservatives.
*Break your bad eating habits to achieve or maintain your desired weight.Lose weight.
*Cleanse your digestive tract of accumulated waste and bacteria.
*Purify all your major organs allowing you to function at your best.
*Reduce cellulite, allergies, acne and obesity safely and naturally.
Administration and Safety Study:
Is hoodia safe for orally taken?
How about the safety of hoodia? It can be a useful weight loss tool in conjunction with exercise and major dietary changes, but it's no miracle weight loss pill. By itself, hoodia (even real hoodia) won't make you look fit and trim, although it can no doubt help you get there if you're willing to exercise and eat right.
Genuine hoodia has a wide safety margin, especially compared to pharmaceuticals. It's a succulent, not a drug, and if you've ever chewed on various cacti (I have), you already know that they taste terrible but certainly don't make you sick. There may be exceptions found in particularly poisonous succulents, but hoodia certainly isn't one of them. Remember: The San tribesmen have chewed on this for eons. Indigenous use of herbs is actually a good indication of long-term safety, despite the frustrating fact that conventional medicine ignores all such cultural evidence.
In the 1990's, the CSIR (Council for Scientific and Industrial Research) in Africa conducted a study on the food that the Bushmen ate. They tested different natural food sources, mostly to ensure that the foods were non-toxic. When they found the Hoodia Gordonii cactus, animal testing was ordered to determine whether the plant was toxic.
Their findings paved the way for the Hoodia Gordonii Cactus Diet, a diet that isn't really a novel concept, but rather an old concept made easy. Since this cactus-style plant is a vegetable, it is also 100% safe and healthy. The Bushmen ate this plant during long journeys in the desert to ward off hunger. The CSIR found some interesting results after animal testing. Hoodia Gordonii Cactus was not toxic. It also caused the animals to lose weight! By 1997, the CSIR isolated P57, the ingredient responsible for the weight loss. The cactus diet was introduced to the general population in 2004.
Suggestive Dosage: Daily suggestive dosage of this appetite suppresant scoped from 500mgs to 3000mgs daily.according to different body weight and conditions.
Toxicity&Risk Studies:
Acute Toxicity of Hoodia Gordonii: Acute toxicity.Oral.Rodent Rat.5000 mgs/kg body weight. No mortality or toxicity was observed.
No mortality was observed following the administration at a very high dose of 5 g/kg body weight.Body weight,feed and water intake in all the rats were comparable with that of the control.
Subchronic Oral Toxicity of Hoodia Gordonii: A Subchronic Toxicity Study was done in Rodent Rat.at 90 mg per kg bodyweight, which is equivalent to the recommended human dosage of 1 gram a day. No mortality or toxicity was observed.
A: Hoodia Gordonii is a succulent in the family Asclepiadaceae. It forms multi-stemmed clumps 45cm (18in) high and bears unpleasant-smelling, pale purple disc-shaped flowers 7.5-10cm (3-4in) in diameter. Hoodia Gordonii grows in semi-arid areas of South Africa. The San people, formerly known as bushmen, of the Kalahari eat the bitter-tasting plant on long hunting expeditions,The species including Hoodia gordonii,Hoodia currorii, and Hoodia lugardii, belong to the genus Hoodia.
The consistent demonstration of the appetite-controlling effects of hoodia has led to massive public interest in the use of this plant as the basis of a dietary supplement for weight control.
Q: Is Natural Hoodia a Drug?
A: No....Natural Hoodia is an all natural dietary supplement and contains NO Caffeine or Ephedra. The major effective content in natural hoodia extracts is the Hoodia Steroidal glycosides and other things such as variable amounts of fiber, organic material, antioxidants,opuntioside I, 4-ethoxyl-6-hydroxymethyl-alpha-pyrone, and kaempferol 7-O-beta-D-glucopyranosyl-(1-->4)-beta-D-glucopyranoside; and a newly identified content: 3-0-[-.beta.-D-thevetopyranosyl-(1.fwdarw.4)-.beta.-D-cymaropyranosyl-(1.f wdarw. 4)-.beta.-D-cymaropyranosyl]-12.beta.-0-tigloyloxy-14-hydroxy-14.beta.-pre gn-50-en-20-one .
Q: Is hoodia steroidal glycosides same as a Cardiac Glycoside?
A: The researchers were intrigued by the fact that hoodia appetite suppresant Steroidal Glycoside is chemically similar to a class of plant-derived compounds called cardiac glycosides from chinese foxglove. These powerful drugs increase the force of contraction of the heart muscle and help maintain normal heart rate and rhythm. A common side effect of the cardiac glycosides is loss of appetite.
Like many drugs, cardiac glycosides act by interacting with specific receptor molecules embedded in the walls of our cells. When stimulated by such interactions, these receptors (which are large, complex proteins that act as molecular channels) initiate a chain of events inside the cell, the net effect of which is the action attributed to the drug. In the case of cardiac glycosides, the receptor molecule is called Na/K-ATPase. Its primary function is to regulate the flow of sodium ions (Na+) and potassium ions (K+) into and out of the cell through the molecular channel, using chemical energy provided by molecules of ATP (adenosine triphosphate). This process, called a sodium/potassium pump, is critically important in maintaining proper cell function and allowing cells to perform certain actions, such as muscle contraction (including that of the heart muscle) and nervous impulse transmission.
Despite the similarities (including the appetite-suppressing effect) between Steroidal Glycoside and cardiac glycosides, however, initial studies with Steroidal Glycoside failed to show any effect on Na/K-ATPase receptors, indicating that Steroidal Glycoside is probably not a cardiac glycoside. Steroidal Glycoside also failed to show an effect on a wide range of other types of receptors. Thus its mode of action at the cellular level was somewhat of a mystery.
Some researchers believe they have pinpointed the active constituent(s) responsible for hoodia appetite-suppressant actions, without much investigation into the plant other potential mechanisms of biological action. However, Hoodia Sppetite Suppresant Steroidal Glycoside may have only been partially identified. Government researchers in South Africa have focused attention on the sterol glycosides. Part of a group of naturally occurring substances called cardenolides, glycosides are best known for their effects on cardiac function. However, measurable effects on Na/KATPase, the target of action of cardiac glycosides, are not believed to be associated with the administration of hoodia.
Q:How does Hoodia formula actually work?
Hoodia formula contain Hoodia Gordonii Cactus extract. the Hoodia cactus contains a molecule Hoodia Steroidal Glycoside that is estimated to be up to 100000 times as potent as glucose in sending a signal to the brain that the body is in a state of satiety, or in common terms: not hungry. and you may read more from the mechanism of Hoodia mentioned above.
Hoodia formula simply takes away your craving for food instantly.
Q:Are Hoodia formula safe?
Yes! Not only are Hoodia formula completely free of dangerous stimulants like Ephedra, Ephedrine, Guarana and Caffeine as well as additives and fillers, Hoodia formula is a 100% natural dietary supplement with no addition of synthetical substances.
Q:What is the suggested usage?How much Hoodia should I use?
For adults,Depending on your current body weight we suggest an intake of 2 formula 1 hour before a meal. Initially take 6 - 8 capsules per day for 5 - 7 days. After that, most people will have good results using only (1) to three (3) capsules about one hour before meals with 8 oz.twice water daily. If you frequently crave a midnight snack, an additional capsule in the evening will help to curb those late-night cravings.
Q:Are there side effects from using Hoodia?
As is commonly known,Hoodia is an all natural herbal dietary supplement. There are no known negative side effects found,no known side effects. When it comes to hoodia side effects there is very little to fear. Not only have all the major studies proven hoodia to be free of serious side effects, the South African government classifies hoodia as "food stuff", not a drug. Moreover, the South African natives (including the children and the elderly) have used hoodia for thousands of years without any known adverse side effects. It appears the only thing to be concerned about is if the hoodia is truly pure genuine South African hoodia. If so, hoodia side effects are practically non-existent.
There Are No Dangerous Hoodia Gordonii Side Effects But How Does It Work?
Hoodia gordonii side effects are for the most part a mystery. Before taking a look at any possible hoodia gordonii side effects lets find out exactly what this fat burner really is.
hoodia gordonii cactus is just that - it's a cactus and it's been creating quite a bit of controversy because of it's being reported as the next breakthrough in fat burners. It's been featured on popular investigative television shows such as 60 Minutes, ABC, and the BBC. There have not been any reported negative hoodia gordonii side effects.
And here's another important fact: in addition to there not being any harmful hoodia gordonii side effects a lot of people believe it to be better than the best fat burners currently available, because unlike most other fat burners, hoodia gordonii cactus has an amazing ability to suppress a persons appetite therefore drastically speeding up the weight loss process.
In short, the p.57 molecule tricks your brain into thinking that you have enough energy in your body and it stops your hunger pains.
It's generally believed that the best hoodia gordonii cactus will only need one or two weeks start working effectively. This is much faster than many of the best fat burners available.
It has been reported however that many people notice the appetite suppressing actions in less than an hour of taking their first dose.
The best way to take hoodia gordonii is with a glass of water about 60 minutes before you eat your meals.
Now, as mentioned earlier, there are no reported bad hoodia gordonii side effects but make sure you do drink an adequate amount of water each day while using it.
The only hoodia gordonii side effects that could be considered to be on the negative side of things, although very minor, is that it can very slightly dehydrate your body.
Other than that there are no reported negative hoodia gordonii side effects. As with any fat burners or weight loss products do your homework and make sure you are getting a pure form of the hoodia gordonii cactus. Many hoodia gordonii fat burners do not contain the pure form of the p.57 molecule and therefore should not be considered.
Q: Are there any side effects?Is there anyone who should not use Hoodia?
A: There are no known side effects.While hoodia is considered very safe and side effect free, we do not feel that women who are pregnant or nursing should use hoodia supplements. In addition, if you have high blood pressure, you may want to check with your Doctor before using a hoodia supplement. It makes sense to always check with your doctor before starting any new supplements program.
Q: How much Hoodia should I use?
A: Most people have positive results taking 1 - 2 capsules an hour before each meal with a large glass of water. Each Pure Hoodia?capsule contains 400mg pure Hoodia Gordonii refined powder. If you frequently crave a midnight snack, an additional capsule in the evening might help to curb those late-night cravings.
Q: How many days does it take to see effects of common hoodia formula.
A: Common hoodia formula 4 to 6 caps daily first month make lose 5~20 Lbs or less in first month depend on different cases.
Frequently Asked Questions:For Distributor
Q: Can we be the Distributor for super Hoodia at local market?.
A:Negotiable and Welcome,we have distributors in many areas.
Distributor friends from other Nation States, Areas and Cities welcomes as normal.
Scientific References:
1.Hoodia.the Succulent Asclepiad Trichocaulon.Natural Arid Hoodia Plus Sense Thirst.How the Hoodia Appetite Suppressant Steroidal Glycoside work?
Claims & Warning:
Claims: Information this web site presented is meant for Nutritional Benefit and as an educational starting point only, for use in maintenance and promotion good health in cooperation with a common knowledge base reference...Furthermore,it based solely on the traditional and historic use or legend of a given herb from the garden of Adonis. Although every effort has been made to ensure its accurate, please note that some info may be outdated by more recent scientific developments......
Pharmakon Warning: The order of knowledge is not the transparent order of forms and ideas,as one might be tempted retrospectively to interpret it; it is the antidote....(Dissemination,Plato's Pharmacy,II.The Ingredients:Phantasms,Festivals,and Paints;138cf. Jacques Derrida.).
And as it happens,the technique of imitation,along with the production of the simulacrum,has always been in Plato's eyes manifestly magical,thaumaturgical:......and the same things appear bent and straight to those who view them in water and out,or concave and convex,owing to similar errors of vision about colors, and there is obviously every confusion of this sort in our souls.And so scene painting (skiagraphia) in its exploitation of this weakness of four nature falls nothing short of witchcraft (thaumatopoia), and so do jugglery and many other such contrivances.(Republic X,602c-d;cf.also 607c).
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MDidea Extracts Professional
Newly Developed Extracts Series:
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Serie No.:R014.Basic Data Sheet Download
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seminal trace...Hoodia Gordonii Extract,Hoodia Cactus Extract.Appetite suppressant P57;P57AS3;Hoodia Powder,Dry Hoodia Powder,Hoodia Powdered extracts,Hoodia Slim Blend,20:1;12:1;10:1,8:1,6:1.Extracts Saps Hoodia Strong...
Botanical Basic Data of hoodia:Natural Arid Hoodia,Miracle Cactus
The Hoodia plant literature:
Acute Toxicity of Hoodia Gordonii: Acute toxicity.Oral.Rodent Rat.5000 mgs/kg body weight. No mortality or toxicity was observed.
Scientific References:
Claims & Warning:
