Arctium lappa L.Great Burdock Achene Extract.Burdock Seed.Burdock Root.

Precautions of Burdock.

Burdock Root Extract INCI Name Arctium Lappa Extract CAS 84012-13-5 EINECS ELINCS No 281-658-8 Great Burdock Achene Extract photo picture image The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, contain active substances that can trigger side effects and that can interact with other herbs, supplements, or medications. For these reasons, herbs should be taken with care, under the supervision of a practitioner knowledgeable in the field of botanical medicine.

Some individuals who handle burdock may experience an irritation of the skin.
Pregnant or nursing women should avoid burdock as it may cause damage to the fetus.
It is best to avoid taking excessive amounts of burdock (especially burdock root) as the toxic effects of this herb are not well understood.

Although in folk medical practices it is believed that burdock lowers blood sugar and may help with diabetes, there is one animal study that suggested that this herb aggravated experimentally-induced diabetes in rats. It is not clear whether this same concern would apply to people.

Because the roots of burdock closely resemble those of belladonna or deadly nightshade (Atropa belladonna), there is a risk that burdock preparations may be contaminated with these potentially dangerous herbs. Be sure to buy products made by established companies with good reputations, and who distribute their products through trustworthy and knowledgeable establishments. Whenever possible, select products with guaranteed potency or standardized extracts.

Some commercially available burdock leaves and roots have been suspected of being adulterated, on occasion, with the root of the deadly belladonna (Atropa belladonna) with toxic consequences to unwary users. Consumers of herbal remedies should find a reliable source for medicinal herbs to avoid hazardous mistakes. Pregnant women should not use burdock, as it has a reported action as a uterine stimulant.

Based on a small animal study, burdock products may promote tightening of the uterus, possibly resulting in a miscarriage. Although no miscarriages have been reported in humans, pregnant women may want to avoid eating or taking burdock.

Burdock belongs to the same family of plants that also includes chrysanthemums, daisies, and ragweed. Individuals who are sensitive to any of these types of plants may also be sensitive to burdock. Additionally, the rough, prickly burrs from burdock may irritate the skin.

Burdock root appears to be safe, even when consumed in large amounts as a vegetable. However, it looks very similar to the roots of belladonna and deadly nightshade, two poisonous plants that may grow in the same areas as burdock. Accidental inclusion of these poisons in burdock root products has resulted in deaths. If you decide to use burdock root, purchase it from a reputable commercial source. Do not try to harvest it from wild burdock plants.

Possible side effects:

No side effects have been associated with using burdock. Since few reliable studies of its use have been conducted in humans, however, it may have side effects that are not yet known. If you experience unexplained side effects while taking burdock, you should stop taking it and tell your doctor or pharmacist about the side effects.

Risks and Notes:

Note: Cases of poisoning have been reported from burdock root products that were mixed unintentionally with the roots of belladonna or deadly nightshade. All three plants look similar and they may grow in the same general environments. Their roots may be impossible to tell apart once they have been collected. If you choose to use burdock root, be sure that it is from a reputable source.

Rarely, burdock root has been found to be contaminated with poisonous material from other plants. Such adulterated products have caused severe illness and death.

Pregnant women should avoid burdock due to a slight potential for causing uterine tightening that could lead to miscarriage. Individuals with allergies to plants in the daisy family should avoid touching burdock.

Safety and Toxicity:

Niu Bang Zi can cause tonic convulsion in frogs, mice, and rabbits: the breathing slows down first, then spontaneous activities decrease, and finally, paralysis sets in without stopping the heartbeat.
Reference:Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Techonology Press; 1998.

Arctiin:
Chemical Name:2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl) methyl]-3-[[4-(Beta-D-glucopyranosyloxy)-3-methoxyphenyl] methyl] dihydro-, (3R-trans)-
Molecular Formula:C27H34O11; Molecular Weight:534.54; Melting Point:110-112 Deg C.

Burdock root extract.Lignans 50%(Arctiin 50% of Total Lignans).Animal test proved that Burdock lignans functions good for lower blood sugar and cholesterol control.
Acute Toxicity.LD50.Oral.Mice.577.6~902.4 times of clinical dose.
LD50.Oral.Rat.495.7 times of clinical dose.
LD50.Intraperitoneal.Mice.119.4 times of clinical dose.
LD50.Intraperitoneal.Rat.22.1 times of clinical dose.
180 days chronic test of Rat at dose 160,80,10.8 times of clinical dose of human prove no toxic effects,and no chronic toxicity.

180 days chronic test of Dog oral dose at 2.13,20,40 times of clinical dose of human shows: at 40 times dose Lignans of burdock do certain harm to liver,kidney tissue and functions,no other kinds of toxic effects,no continuous toxic effects. No any toxic effects appear at lower dose such as 2.13 and 20 times groups.

Reference:

1.Arctium lappa L.Great Burdock Achene Extract.Burdock Seed.Burdock Root.

last edit date:3rd,Mar.2010.

Available Product

Name:Burdock Root Extract
Serie No:R025.
Specifications:10:1.TLC.
INCI Name:ARCTIUM LAPPA EXTRACT
EINECS/ELINCS No.:281-658-8
CAS:84012-13-5
Chem/IUPAC Name:Arctium Lappa Extract is an extract of the roots of the burdock,Arctium lappa,Compositae

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