The Spine Date Seed or Chinese Sleeping Elixir,What is Semen Ziziphi Spinosa?
- Brief Info and Botanical Description.
- Name Identification.
- Phytochemicals and Constituents.
- Research of Zizyphus spinosa seed.
- Traditional Theory of Insomia due to fatigue.
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- Wild jujube seed helps to sleep well:Mechanism.
- Indication of Jujube Seed:A liver-healthy anti-anxiety Herb.
- How Search engine think about Jujube.
- Research Update:Zizyphus spinosa.
Phytochemicals and Constituents.:
Major effective as jujuboside A,jujuboside B,betulinic acid,betulin,jujuba flavones,proteins, rich of Vitamine C, etc.
Chemical Composition:Zizyphusine; Caaverine; Amphibine D; Sanjoinenine; Lysicamin; Juzirine; Betulinic acid; Betulin; Daucosterol; Jujuboside A, B; Ceanothic acid; Alphitolic acid; Threonine; Valine; Methionine; Leucine; Isoleucine; Lysine; Phenylalanine; Ferulic acid; N-methylasimilobine; 5-hydroxy-6-methoxynoraphine; Cyclic adenosine 3', 5'-monophosphate; Sanjoinine A, B, D-F, G1, G2, Ia, Ib, K.
Sedative Constituents of Zizyphus:
Laboratory animal studies of zizyphus extract confirm a sedative effect, though the constituents that contribute this effect have not all been specifically identified. Some sedative effects were shown to be produced by several different components. The only components of zizyphus that are present in quantities likely to be responsible for the observed clinical effects are triterpenes. The unique triterpenes for this herb are known as jujubosides (see pictures). Additionally, there are related triterpene compounds (such as betulic acid and oleanolic acid) that are found in several other herbs. Structurally, the jujubosides are nearly identical to the active constituents found in ginseng, an herb that is traditionally used as a sedative and a tonic. According to one analysis, the triterpene level in zizyphus is 2%, so that an 18 gram dose, as used in Zizyphus Combination, would yield about 300 mg of triterpenes, a level typically relied upon for most triterpenes. The simple powder of zizyphus, consumed orally, appears to be effective in relatively low dosage. One report indicates that good effects were obtained using 0.8-1.2 grams of the powder before bed.
In one of the best known patent remedies for insomnia, Tianwang Buxin Dan (Ginseng and Zizyphus Formula), many herbs with triterpenes are combined together, including zizyphus, ginseng, platycodon, and polygala. The formula also provides herbs that contain steroid saponins (e.g., ophiopogon and asparagus) that have a similar structure and that are likely to have similar effects. The indications and applications of this large formula are almost identical to that of the smaller and more ancient Zizyphus Combination. The famous tonic mushroom ganoderma contains triterpenes similar to those found in ginseng and zizyphus, and is classified, like zizyphus, as a tonic sedative. It is sometimes recommended as a single herb remedy for insomnia.
- 1.The Spine Date Seed or Chinese Sleeping Elixir,What is Semen Ziziphi Spinosa?
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