Common Motherwort Leonurus Cardiaca Motherwort Herb Extract.

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Constituents and Phytochemicals:Motherwort.Leonurus Cardiaca.

Motherwort Herb Extract Leonurus Cardiaca photo picture image Constituents: alkaloids (including leonurine and stachydrene), iridoid glycoside (leonuride), iridoid glycosides (including leonurin and leonuridine), diterpenoids (including leocardin), flavonoids (including rutin, quercetin, hyperoside and apigenin), volatile oil, tannins, vitamin A.

 Phytochemicals:

 Iridoids: leonuride and others not yet identified

 Diterpenes of the labdane type, such as leocardin, a mixture of two epimers of 8[[beta]]-acetoyx-9[[alpha]], l3[[alpha]], l5, l6-bisepoxy-l5-hydroyx-7-oxo-labdan-6[[beta]], l9-olide (This is why shorter names are coined!)

 Flavonoids:rutin, quinqueloside, genkwanin, quercitin, quercetin, isoquercetrin, hyperoside, and apigenin and kaempferol glucosides.

 Caffeic acid 4-rutinoside. Motherwort Herb Extract Leonurus Cardiaca photo picture image

 Leonurine is the uterotonic principle of Leonurus artemisia. Scientists have developed a simple, high-yield synthetic procedure of 1 that is adaptable to large scale preparation. The synthesis involves the condensation of syringic acid and 4-guanidino-1-butanol hydrochloride in the presence of DDC using 1:1 HMPT-ether as solvent. The synthetic leonurine showed uterotonic activity in vivo and in vitro.

 The uterotonic principle of Leonurus artemisia, a plant leaf, is leonurine. This paper reports the development of a simple, high-yield synthetic procedure of reproducing leonurine that is adaptable to large-scale preparation. The synthetic process includes condensation of syringic acid and 4-guanidino-1-butanol hydrochloride in the presence of dicyclohexylcarbodiimide, using 1:1 hexamethylphosphoric triamide-ethyl ether as solvent. Synthetic leonourine showed uterotonic activity in vitro and in vivo, just like its naturally occurring counterpart.

 Leonurine is easily extracted into water and its derivative compound is hydrochloride monohydrate. Primary uses include (1) Respiratory tract infections caused by Streptococcus pneumoniae and group A hemolytic streptococci. (2) Otitis media due to S. pneumoniae, Hemophilus influenzae, Moraxella catarrhalis (use monohydrate only), staphylococci, streptococci, and N. catarrhalis. (3) GU infections (including acute prostatitis) due to Escherichia coli, Proteus mirabilis or Klebsiella species. (4) Bone infections caused by P. mirabilis or staphylococci. (5) Skin and skin structure infections due to staphylococci and streptococci.

 Motherwort contains Stachydrine; Leonurine; Prehispanolone; Hispanolone; Preleoheterin; Leoheterin; Galeopsin; Preleoheterin; Lavadulifolioside; Verbascoside; Leonoside A and B; Humulene; Leosibirin; Leosibiricin; Preliosibirin; Arginine; Leonurine nitrite; 4-guanidino-1-butanol; 1-octylene-3-alcohol; Trans-caryophyllene.

 Inorganic Chemicals:It also contains many trace elements, such as Zn, Cu, Mn, Fe, Ni, Pb, As, Se, Ge, and Rb, among which Fe, Mn, Zn, and Rb are of relatively high content levels.

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Reference:

citations1.Common Motherwort Leonurus Cardiaca Motherwort Herb Extract.

last edit date:27th,May.2009.