Prunella vulgaris All heal Selfheal Fruit-spike.immune stimulant and anti-inflammatory effects.
Article Content:
- .Botanical Info of Prunella vulgaris.
- .Prunella spike,Name Origin and Species.
- .Plant Description of Prunella in General.
- .Constituents and Phytochemicals of Prunella Valgaris and Prunella herb.
- .History and Uses:Heal All,All Heal and Self Heal.
- .Functions and Actions of Prunella spike.
- .Prunella vulgaris Pharmaceutical Actions.
- .Suggestions and Administrations:Prunella vulgaris.
- .Research update:Prunella vulgaris.
Constituents and Phytochemicals of Prunella Valgaris and Prunella herb.
Main Effective Constituents:Luteolin,C15H10O6;Esculetin,C9H6O4.
Ursolic acid and caryophyllin (they are the saponin).Contains prunellin,a kind of saponin, it's aglycon just Ursolic acid,other kinds of content such as Ursolicacid,Oleanolic Acid,Rutin,hyperin, alpha-anisylacetone,delphinidin,cyanidin. Seed contain coating oil and lipase. Herb contains naphtha,composed by D-Camphor and fenchone,Vitamine B1,etc.
Whole herb contains triterpenoid saponins,Sapogenol is Oleanolic Acid,free Oleanolic Acid,Ursolic Acid,Rutoside,Hyperin,Caffeic acid,VitaminB1,Vitamin C,Vitamin K,Beta-Carotin,Resins,Bitterness,Tannins,Volatile oil,Alkaloid,water soluble salt(3%,and potassium chloride shares about 63%)
Fruit Spike contains Delphinidin,Cyanidin,d-Camphor,d-fenchone,Ursolic Acid.
Chemical Composition:Oleanolic acid (I); b-amyrin (II); Stigmasterol-7; 22-diene-3-ketone (III); a-Spinasterol (IV); b-sitosterol (V); Daucosterol (VI); 1.8-cineole; b-pinene; Myrcene; Linalool acetate; a-phellandrene; Linalool; Ursolic acid (II); Quercetin (VI); Quercetin-3-o-b-D-galactoside (V); Oleanane-12- alkene- 3b; Oleanane-12-alkene-28-aldehyde- 3b-hydroxy (VII); Vulgarsaponin B (VI, III, V); Ursaane-12- alkene-28-aldehyde-3a-hydroxy (VIII); 28-dihydroxy (IX) and ursaane-12- alkene-3b; 28-dihydroxy (X), IV, VII, VIII, IX and X; 2a, 3a-hydroxyuvaol-12- alkene-28- acid (III); 3b, 16a, 24-trihydroxyoleanane-12-alkene-28-acid-3-o-(6-butyryl)- b-D-glucopyraoside (I).
Other Phytochemicals:Ursolic acid,betulinic acid;2alpha,3alpha-dihydroxyurs-12-en-28-oic acid;2alpha,3alpha,24-trihydroxyurs-12,zo(30)-dien-28-oic acid;2alpha,3alpha,24-trihydroxyolean-12-en-28-oic acid;2alpha,3alpha,24-trihydroxyolean-11,13(18)-dien-28-oic acid;(12R,13S)-2alpha,3alpha,24-trihydroxy-12,13-cycle-taraxer-14-er-28-oic acid;(13S,14R)-2alpha,3alpha,24-trihydroxy-13,14-cycle-olean-11-en-28-oic acid;delphinidin;cyanidin;rosmarinic acid;isoorientin;cinaroside;beta-sitosterol-beta-D-glucoside;sigmast-7-3beta-ol-beta-D-glucoside;dpinasterol-beta-D-glucoside;umbelliferone;scopoletin;vulgarsaponin B;quercitin;quercitin-3-O-beta-D-galactoside;ethyl caffeate;vulgarsaponin A;stigmasterol;caffeic acid;alpha-Spinasterol;volatile oil.
Volatile oil:contains 6,10-dimethyl-2-undecanone,2.828%;hexadecanoic acid,17.155%;9-Octadecenoic acid,0.361%;isochiapin,2.061%;d-camphor;d-fenchone,etc.
Prunella vulgaris widely used as herb medicine to treat and prevent many disease, also used widely recent years for it's good taste and rich nutrition,scientific data proved that the fresh leaves and stem of Prunella vulgaris rich in protein,plant fat, carbohydrate,Carotene,Vitamine B, and nicotinic acid (niacin,Vitamine B3)
1.1.Sugar:Prunella vagaris contains free monosaccharide,disaccharides and polysaccharides.Scientists ever isolated and identified chemicals from Big flower Prunella(Prunella grandiflora Jacq.) free glucose,galactose,fructose,sucrose,combinative mannitose,glucose,Arabinose,xylose and Rhamnose.Tabba and other scientist isolated a kind of polysaccharide from prunella vagaris water extract and identified it as prunellin,molecular weight about 10000,sulfur shares the composition of its molecular.
1.2.Sterol content:Scientists isolated 8 sterols from the fruit spike,stem and leave of prunella herb,4 of them are free sterols,another 4 of them are combinative Glucoside.They are beta-sitosterol, Stigmasterol,Spinasterol, Glucoside and Beta-Amyrin,etc.Another kind of new glucopyranoside chemical isolated recently and named as vulgarsaponin B.
1.3.Organic acids:Organic acids isolated from prunella vagaris mainly composed of Caffeicacid,oleic acid,linoleic acid,Lauric acid,Palmitic acid,myristic acid,Stearic acid and lignoceric acid.GC-MS method applied by scientists of China isolated palmitic acid(PA),Ethyl hexadecanoate;6,9-Octadecadienoic Acid ;Stearic acid;3,6,7-Eicosatrienoic Acid;Oleic acid;Arachidonic acid and behenic acid.Scientists Wan Ju Zhu and others isolated and identified a new kind of organic acid:2alpha,3alpha-dihydroxyurs-12-en-28-oic acid.
1.4.Flavones:Flavones from prunella herb identified till present mainly flavone,flavonol,anthocyanin and anthocyanidin.They are Quercetin, anthocyanin,delphinidin,hyperin,Luteolin-7-O-glucoside,etc.
1.5.Steroids:White flower Prunella(Prunella vulgaris L.var, leucantha Schur Sec.Bailey) contains cyasterone,it shows anti tumor activity.
1.6.Coumarins:Russia scientists isolated 3 kind of coumarins from prunella herb,identified as Umbelliferone,(Scopoletin and Aesculin.
Reference:
1.Prunella vulgaris All heal Selfheal Fruit-spike.immune stimulant and anti-inflammatory effects.




