Properties of Atractylodes lancea Rhizome(Cang Zhu).
Article Content:
- .Botanical Info of Atractylodes lancea Rhizome(Cang Zhu) and Rhizoma Atractylodes Macrocephalae (Bai Zhu).
- .Atractylodes lancea Rhizome(Cang Zhu) Introductions.
- .Properties of Atractylodes lancea Rhizome(Cang Zhu).
- .Phytochemicals and Constituents.
- .Effects of Atractylodes lancea Rhizome(Cang Zhu) and Rhizoma Atractylodes Macrocephalae (Bai Zhu).
- .Applications of Atractylodes lancea Rhizome(Cang Zhu).
- .Indications and Pharmacology:Atractylodes lancea Rhizome(Cang Zhu).
- .Indications and Pharmacology:Rhizoma Atractylodes Macrocephalae (Bai Zhu).
- .Dosage and Administration.
- .Research Update:Atractylodes lancea Rhizome(Cang Zhu) and Rhizoma Atractylodes Macrocephalae (Bai Zhu).
Phytochemicals and Constituents.
violet oil,atractylodin,beta-eudesmol,hinesol,hydroxy-atractylon,etc.
Phytochemicals: (-maaliene; a, d-Guaiene; Chamigrene; Caryophyllene; Elemene; Humulene; Selinene; Patchoulene; 1,9-aristolodiene; Guaiol; Elemol; Atractylon; 4(-ethanonaphthalene; Atractylodinol; Acetyl atractylodinol; (-bisabolol; Atractylodin; Hinesol; (- eudesmol; Furaldehyde; 3b-acetoxyatractylon; 3b-hydroxyatractylon; Butenolide B; Tryptophane; 3,5-Dimethoxy-4-glucosyloxy; Selina- 4(14),7(11)-diene- 8 one; ( 2-carene,1,3,4,5,6,7-hexahydro-2,5,5-trimethyl-2H-2; ( 2- (1,4a-dimethyl-3-glucosyloxy-2-oxo-2,3,4,4a,5,6,7,8-octahydronaphthalen-7-yl)- isopropanol glucoside; ( 2-(8-methyl-2,8,9-trihydroxy-2-hydroxymethyl-bicyclo[5.3.0]decan-7-yl)isopropanol glucoside; ( 2-(8-methyl-2,8-dihydroxy-9-oxo-2-hydroxymethyl-bicyclo[5.3.0]decan-7-yl) isopropanol glucoside; ( 2-(1,4a-dimethyl-2,3-dihydoxydecahydroxynaphthalen-7-yl) isopropanol glucoside.
Inorganic Chemicals:Co, Cr, Cu, Mn, Mo, Ni, Sn, Sr, V, Zn, Fe, P, Al, Zr, Ti, Mg, Ca.
The investigation of the aromatic oils is a key to understanding the atractylodes herbal materials, particularly cangzhu. Atractylodes lancea is rich in a volatile oil, making up 3.5-7% of the dried rhizome, with atractylodin, beta-eudesmol, hinesol, elemol, atractylone, and beta-selinene; A. chinensis and other substitute species have less essential oil. The main constituents in the essential oils from the rhizome of A. chinensis are beta-eudesmol and atractylone; A. lancea also has hinesol as a major constituent. beta-eudesmol is a major component of the essential oil of magnolia bark, an herb in the same Materia Medica category as cangzhu. The fraction comprising the combination of hinesol and eudesmol in A. lancea is called atractylol, and this is the reddish substance appearing on the surface of the sliced rhizome, giving the name red atractylodes.
Atractylodes macrocephala (baizhu) has less essential oil than the cangzhu varieties, with only 0.35-1.35% and with atractylone as the main component, along with smaller amounts of other lactones having similar structure. The differences in chemical composition help confirm that the two herbs (cangzhu and baizhu) may have differing properties, further justifying their separation in the Materia Medica.
Since white atractylodes has little essential oil, and even less of it after being fried (the heat drives off or destroys volatile components), other active ingredients may be present to explain its functions. A component called atractylenolide (a group of sesquiterpene lactones; three noted thus far) is found in baizhu; this component increases with frying of the herb (highest in lightly fried herb, which has turned yellowish, not brown). In terms of the atractylodes effects, it is thought that these components may serve as antispasmodic agents, thus reducing intestinal contractions associated with diarrhea. Diuretic action, measured in laboratory animal experiments, has been attributed to both volatile and non-volatile compounds of atractylodes, including ?-eudesmol, sesquiterpene lactones, and polyacetylenes.
Atractylodes lancea Thunb contains 5~9% of essential oil. The main ingredients of the oil consist of atractylo, hinesol), beta-eudesmol etc.
Atractylodes chinensis (DC.) Koidz. contains 1.5% of essential oil. The main ingredients of the oil consist of atractylol, atractylone, hinesol, beta-eudesmol etc.
Atractylodes japonica Koidz. Kitam contains 1.5% of essential oil. The main ingredients of the oil consist of atractylol, atractylone, hinesol, beta-eudesmol, atractylodin, atraetylin, atractylone etc.
Phytochemicals of Rhizoma Atractylodes Macrocephalae (Bai Zhu):
2-furaldehyde, 3-beta-acetoxyatractylon, 3-beta-hydroxyatractrylon, Acetylatractylodinol, Atractylodin, Atractylodinol, Atractylon, Beta-eudesmol, Beta-selinene, Calcium, Copper, Elemol, EO, Furfural, Hinesol, Iron, L-alpha-bisabolol, Magnesium, Manganese, Potassium, Sodium, Zinc
Reference:
1.Atractylodes lancea Rhizome(Cang Zhu) and Rhizoma Atractylodes Macrocephalae (Bai Zhu).




