Griffonia Seed and 5-HTP (5-hydroxy tryptophan),the magic seed from African folk medicine not only play as effective replacement for tryptophan,but more.

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Pharmacology of 5-HTP(5-hydroxy tryptophan).

Griffonia Seed Extract 5-Hydroxytryptophan 5HTP CAS 4350-09-8 photo picture image Low serotonin levels are believed to be the reason for many cases of mild to moderate depression which can lead to symptoms like anxiety, apathy, fear, feelings of worthlessness, insomnia and fatigue.

 5-HTP enhances the activity of serotonin,a hormone produced by the brain that is involved in mood, sleep and appetite.

 Decreased levels of this neurotransmitter has been associated with depression, insomnia, obsessive/compulsive disorders as well as eating disorders leading to obesity, or the reverse/bulimia.

 In a study employing positron-emission tomography(PET) scanning, eight healthy volunteers and six people diagnosed with major depression received infusions of radio labelled 5-HTP.

 The researchers found that significantly less 5-HTP crossed the blood-brain barrier into the brains of the depressed subjects than into the brains of the normal controls1. A significant reduction in anxiety was observed on three different scales designed to measure anxiety2. In a study of 20 people with panic disorders, several experienced a feeling of "relief" after receiving 5-HTP. A group of Italian researchers reported that 20 obese patients taking 5-HTP (900 mg/day) lost a significant amount of weight, had less carbohydrate intake, and consistently became sated earlier than a similar group taking a placebo.

 Therapeutic Uses:It alleviates the effects of a variety of conditions, including depression, anxiety, insomnia and obesity.

 Tryptophan hydroxylase (TrpOH) catalyzes the conversion of tryptophan to 5-hydroxy-tryptophan, which is the initial and rate-limiting enzyme in the synthesis of the hormone serotonin. It is also the first enzyme in the synthesis of melatonin. TrpOH is a member of the aromatic amino acid hydroxylase family, so it shares many structural and biochemical properties with PheOH and TyrOH. Decreased levels of serotonin have been implicated in a wide variety of physiological functions and behaviours, such as appetitive, emotional, motor, cognitive and autonomic.

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citations1.Griffonia Seed and 5-HTP (5-hydroxy tryptophan),the magic seed from African folk medicine not only play as effective replacement for tryptophan,but more.

last edit date:2nd,June.2009.