Eucommia bark,Duzhong and its Applicable Uses.
Contents:
- Basic Botanical Data of Eucommia Bark.
- What is eucommia bark? What is it used for?.
- Eucommia Bark Varieties and Grading.
- Phytochemicals and Constituents of Eucommia Bark.
- Pharmacology:Eucommia Bark.
- Eucommia Bark Indications and Combinations.
- Primary Combinations of Eucommia Bark.
- Eucommia Bark Dosage and Administration.
- Scientific Data and Mechanism:Eucommia Bark Hypotensive Effects.
- Research update:Eucommia bark.
Pharmacology:Eucommia Bark.
Properties: Sweet in flavor, warm in nature, it is related to the liver and kidney channels.Eucommia Bark is the rare medicinal herb with stable property, sweet and slight-pungent taste, and no poison. It exerts effects of tonifying liver and kidney, strengthening muscles and bones, reducing blood pressure and blood fat, and anti-abortion, etc.
Functions: Tonifys the liver and kidney, strengthens skeletal system, and prevents abortion.Eucommia bark is commonly used in Chinese herbalism, where it is considered to be one of the 50 fundamental herbs. It is considered to be an excellent tonic for the kidneys and liver, and is thought to act specifically on the lower part of the body. Major functions of it are to treat hypertension, dizzy feeling, mild lumbago, kidney deficiency, and frequent micturition, ect. With the "Chinese medicine fever" rising in many countries of the world, the demand for Eucommia Bark is increasing at a fast pace.
Effects on the heart:
Experiments show that administered to guinea pigs, the leaves of Du Zhong (0.2g/guinea pig) can significantly increase the subjects' coronary blood flow. Du Zhong also has a preventive effect on experimental myocardial ischemia in rabbits: the bark and leaves of Du Zhong were administered to rabbits via intravenous injection for four consecutive days, and the pathological results showed that there were no significant hemorrhage, necrosis, or cicatrix formation in the rabbits' endocardium and epicardium; there were dilation and congestion in the capillaries and some larger vessels and there were varying degrees of inflammatory cell infiltration in the endocardium, epicardium, and myocardium.
Lowering blood pressure:
The zinc/copper ratio in the erythrocyte of hypertension patients fluctuates around 15.04- 2.50, which is significantly higher than that in healthy people. Du Zhong can lower the zinc/copper ratio, and the blood pressure.The blood pressure of anaesthetized canine can be lowered significantly by intravenous injection of Du Zhong decoction. At the dosage of 0.4 g/kg, the lowered blood pressure began rising again after five minutes. When the dosage is increased to over 1 g/kg, however, the blood pressure-lowering effect of Du Zhong can be sustained for a relatively long period of time.
Anti-inflammatory and anti-viral effects:
Chlorogenic acid, an active component of Du Zhong, has a pronounced anti-bacterial effect.Aucubin is a significant protector of the liver; it can inhibit the duplication of the DNA of hepatitis B. Although aucubin in and of itself does not have an anti-viral effect, its being cultivated with glucosiduronidase produces an anti-viral effect.
Effects on immunity:
Alcohol-based extract of Du Zhong can promote ConA-induced proliferation of splenic cells, and enhance the phagocytic function of the peritoneal macrophage phagocytosis. But it does not seem to affect splenic antibody formation cells.Du Zhong decoction has a bi-directional regulatory effect on the cellular immune system. It can inhibit DNCB-induced delayed hypersensitivity, counteract hydrocortisone-induced decrease in T-lymphocyte percentage. It can also increase the percentage of T-lymphocytes in the peripheral blood of S180 mice, and strengthen the phagocytic function of the peritoneal macrophage.Various parts of Du Zhong (cortex, leaves, twigs, and regenerated peel, etc.) can elevate the cAMP content in the plasma, indicating a regulatory effect on cyclo-nucleotide metabolism.
Tranquilizing and analgesic effects:
Experiments show that Du Zhong can enhance mice's endurance against exogenous stimulation, and has central tranquilizing effects.Du Zhong also has a significant analgesic effect (P less than 0.01).
Anti-aging effects:
Experiments show that water-based extract of Du Zhong can protect mice from superoxidation injuries due to D-galactose-induced aging.Du Zhong is also shown to increase the activity of GSH-Px in aged mice, increase the activity of SOD and the weight of the adrenal gland in mice of suffering from experimental yang-deficiency.
Reference:
1.Eucommia bark,Duzhong and its Applicable Uses.
last edit date:4th,Mar.2010.
- Name:Eucommia Bark Extract
- Serie No:R053.
- Specifications:5:1TLC.
- INCI Name:EUCOMMIA ULMOIDES EXTRACT
- EINECS/ELINCS No.:N/A
- CAS:223749-00-6
- Chem/IUPAC Name:Eucommia Ulmoides Extract is an extract of the dried leaves of Eucommia ulmoides,Eucommiaceae





