White Peony Root,Radix Paeoniae Alba,Bai Shao and Red Peony Root,Radix Paeonia Rubra,Chi Shao,Origin,function,Phytochemicals and Modern Researches.

Pharmacological Action of of White Peony Root.

Peony Root Extract INCI Name Paeonia Albiflora Root Extract CAS 084929-40-8 Paeoniflorin 23180-57-6 White Peony Root Extract Radix Paeoniae Alba Red Peony Root Extract Radix Paeonia Rubra photo picture image Properties: Bitter, sour and sweet in flavor, slightly cold in nature, it is related to the liver and spleen channels.

Functions:

Replenishes blood, regulates menstruation, suppresses hyperactivity of liver-yang and astringes yin to arrest sweating.

White peony root has been used for over 1,500 years in Chinese medicine. It is known most widely as one of the herbs used to make 'Four Ingredients Soup (Si Wu Tang)', a woman's tonic, and it is also a remedy for gynaecological problems and for cramp, pain and giddyness.

As a sweet and sour herb, this has yin-forcing effect, hence, it can replenish blood of the liver and nourish liver-yin; being bitter and cold in property, it can also suppress hyperactivity of liver-yang and clear liver-fire, supplement its deficiency and reduce its hyperactivity.

It is thus a main herb for treating liver and is often used to treat syndromes of hyperactivity of liver-yang due to yin-deficiency, failure in nourishing liver due to blood-deficiency, night sweat due to yin-deficiency and blood deficiency.

1. Dilating the coronary artery and blood vessels of hind legs in dogs.
2. Lowering blood pressure transiently.
3: Inhibiting the intestines in rabbits in vitro.
4. Its component paeoniflorin inhibits the central nervous system.
Peony Root Extract INCI Name Paeonia Albiflora Root Extract CAS 084929-40-8 Paeoniflorin 23180-57-6 White Peony Root Extract Radix Paeoniae Alba Red Peony Root Extract Radix Paeonia Rubra photo picture image

Immunoregulatory effects:

Total glycosides of peony (TGP), paeoniflorin (PF), and TGP minus PF all have a concentration-dependent effect of increasing the low spleen lymphocyte proliferation in rats of adjuvant arthritis (all with a bell-shaped dose-effect relationship) and all can inhibit the peritoneal phagocytes' overproduction of IL-1 in rats of adjuvant arthritis (all with a reversed bell-shaped dose-effect relationship). In both instances, the effect of TGP is the most pronounced of the three.(Ge Zhi Dong, et al. Chinese Pharmacology Bulletin. 1995;11(4):303-305.)

Counteracting arthritis:

Administered to rats with adjuvant arthritis, TGP can not only inhibit foot swelling, they can also lower the elevated levels of MDA, NO2, and TNF, while raising the sagged activities of SOD, GSH-Px.(Wang Bin, et al. China Journal of Pharmacology andToxicology. 1996;10(3):211-214.)

Protecting the liver:

Experiments show that Bai Shao has a dosage-dependent inhibitory effect on hepatic lipid peroxidation.(Jiang Hui Di, et al. Journal of Traditional Chinese Medicine Material. 1997;20(12):624-626.)

Laxative effects:

Research shows that Bai Shao can directly act on the intestines, increasing mucus secretion in the large intestines, enhancing movement, and increasing the water content in both the small and large intestines.(Tan Jun Jia, et al. China Journal of TCM Science and Technology. 1998;5(3):1550157.)

Effects on the activity of ATPase:

Experiments show that TGP of relatively high concentrations can significantly increase the activity of Ca+|-Mg+|-ATPase and Na+|-K+|-ATPase, and decrease the concentration of cytoplasmic free calcium ions.(Wang Bin, et al. Journal of Anhui Medical University. 1998;33(3):176-177.)

Effects on the cardiovascular system:

TGP can cause vasodilation in isolated rabbit ears.They can also significantly lengthen mice's survival time from oxygen deprivation under normal pressure. They can improve the cardiac function of rabbits of pituitin-induced myocardial ischemia. These effects are dosage-dependent.(Wang Qian Mao, et al. Chinese Pharmacology Bulletin. 1986;2(5):26.Zhu Xiao Guang, et al. Chinese Pharmacology Bulletin. 1999;15(3):252-254.)

Reference:

1.White Peony Root,Radix Paeoniae Alba,Bai Shao and Red Peony Root,Radix Paeonia Rubra,Chi Shao,Origin,function,Phytochemicals and Modern Researches.

last edit date:5th,Mar.2010.

Available Product

Name:Peony Root Extract
Serie No:R083.
Specifications:10:1 TLC,Paeoniflorin 10%,20%,90%HPLC.
INCI Name:PAEONIA ALBIFLORA ROOT EXTRACT
EINECS/ELINCS No.:N/A
CAS:084929-40-8,Paeoniflorin 23180-57-6.
Chem/IUPAC Name:Paeonia Albiflora Root Extract is an extract of the roots of the peony,Paeonia albiflora,Paeoniaceae

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