White Peony Root,Radix Paeoniae Alba,Bai Shao and Red Peony Root,Radix Paeonia Rubra,Chi Shao,Origin,function,Phytochemicals and Modern Researches.
Article Content:
- .Basic Botanical Data Identification of White Peony Root.Radix Paeoniae Alba.
- .Botanical Description of White Peony Root.
- .Botanical Description of Red Peony Root.Radix Paeonia Rubra.Chi Shao.
- .Origin of of White Peony Root.Radix Paeoniae Alba.
- .Phytochemicals and Constituents of of White Peony Root and Red Poeny Root.
- .Functions of of White Peony Root.
- .Common medicinal uses of of White Peony Root.
- .Pharmacological Action of of White Peony Root.
- .Pharmacological Action of of Red Peony Root.
- .Uses and combinations of of White Peony Root.
- .How to take of White Peony Root.
- .Precautions and Cautions on Use of White Peony Root.
- .Safety and Acute toxicity.
- .Modern Researches of White Peony Root,Red Peony Root.Paeoniflorin and Peony Root Extract.
Safety and Acute toxicity.
Acute toxicity(LD50):White Poeny Root LD50 (mice): 81g/kg (oral/decoction), 125mg/kg (i.p./TGP), 3.53g/kg (paeoniflorin).Reference:Li Jin Cai. Traditional Chinese Medicine Bulletin. 1987;12(8):54.Wang Yong Xiang. Journal of Anhui Medical University. 1986;2(1):11.Herbal Information Center. State Drug Administration of China. Active Components of Medicinal Herbs. People's Health Press. 1986.
Acute toxicity(LD50):Red Poeny Root MTD (mice/IV injection/water-based extract): 50g/kg. MLD (cats/IV injection/water-based extract): 186g/kg. LD50 (mice/abdominal injection): 4.6g/kg (Chi Shao D), 2.9g/kg (Chi Shao C), 10.8g/kg (Chi Shao A).Reference:Editorial Committee of Chinese Materia Medica. State Drug Administration of China. Chinese Materia Medica. Shanghai: Science and Technology Press; 1998.
Paeoniflorin Identification
Chemical name:Paeoniflorin
CAS No.:23180-57-6. Molecular Formula:C23-H28-O11. Molecular Weight:480.51
Synonyms:5beta-[(Benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1alpha(2H)-yl-beta-D-glucopyranoside
Acute toxicity(LD50):Paeoniflorin
LD50:Lethal dose,50 percent kill. Intraperitoneal. Rodent-mouse. 3530mg/kg.Toxic Effects:Behavioral-somnolence(general depressed activity).
LD50:Lethal dose,50 percent kill. Intravenous.Rodent-mouse.9530mg/kg.Toxic Effects:Behavioral-sleep. Behavioral-somnolence(general depressed activity).
Reference:YKKZAJ Yakugaku Zasshi.Journal of Pharmacy.No.1-1881-Volume(issue)/page/year:89,899,1969
Reference:
1.White Peony Root,Radix Paeoniae Alba,Bai Shao and Red Peony Root,Radix Paeonia Rubra,Chi Shao,Origin,function,Phytochemicals and Modern Researches.
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