Description and remedy use of Tall Gastrodia Tuber,Rhizoma Gastrodiae and its Determination Method...

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Actions and Pharmacology of Tall Gastrodia Tuber:Rhizoma Gastrodiae.

Tall Gastrodia Tuber Extract Tianma Rhizoma Gastrodiae Extract Gastrodia elata Bl Extract photo picture image 1. Calming the endopathic wind and relieving convulsion and spasm.
 2. Calming the liver and suppressing liver-yang.
 3. Removing obstruction in the channels to relieve pain.
 4. Vertigo, dizziness, headache
 5. Hypertension
 6. Facial palpsy, hemiplegia, cerebral vascular accident, numbness of extremities
 7. Infantile convulsions, epilepsy

 Gastrodia Tuber Pharmacology:

 Effects on cardiac muscles:

 Experiments show that Tian Ma solution can decrease the number of pathologic Q-waves number in the electrocardiogram of the precardium, after ligation at the left ventricle branch of the coronary artery. It can also reduce the level of propionic aldehyde, a product of lipid peroxidation in the serum, and shrink the area of cardiac infarction.Furthermore, research shows that used in combination with intra-aortic balloon counterpulsation, Tian Ma solution has a significant synergistic effect of restricting the area of myocardial necrosis.(Luo Hong Ling, et al. Journal of Huaxi Medical University. 1992;23(1):53-56.Luo Hong Ling, et al. Journal of Biomedical Engineering. 1997;14(3):296-298.)

 Effect on the cardiovascular system:

 Intravenous injection of Tian Ma at 1g/kg has the following effects: 1) decreasing resistance in the blood vessels in the hindquarter and head of rabbits; 2) significantly increasing perfusion flow into isolated rabbit ears; 3) counteracting adrenalin-induced decrease in blood flow; and 4) increasing cerebral blood flow and coronary blood flow in isolated guinea pig hearts. Intraduodenal medication (10g/kg) or abdominal injection (5g/kg) can reduce the blood pressure and slow down the heart rate in rats. Intravenous injection to rats at 2g/kg can significantly prevent changes in electrocardiogram due to pituitrin-induced myocardial ischemia.(Ren Shi Lan, et al. Journal of Chinese Materia Medica. 1992;23(6):302-304.Ren Shi Lan, et al. Journal of Chinese Materia Medica. 1992;23(6):302.)

 Sedative and analgesic effects:

 Experiments show that administered at 5g/kg i.p., Tian Ma can significantly reduce the level of DA in the cortex (P less than 0.05) and in three other cerebral areas. It is speculated that Tian Ma's sedative and analgesic effects may be related to reducing DA in the brain.Cultivated Tian Ma can strengthen the hypnotic effect of sub-threshold dose of pentobarbital sodium in mice.(Huang Shan, et al. Guizhou Journal of Medicine. 1993;17(1):14-15.Zhang Jun Ying, et al. Journal of Traditional Chinese Medicine Material. 1992;15(3):37-40.)

 Effects on inflammation and immunity:

 Tian Ma solution can strengthen mice's non-specific immunity and the immune response of T cells. It can also promote the formation of specific humoral antibody and the integration of specific antigens with cells.Moreover, Tian Ma (5g/kg) can inhibit agar-induced swelling in mice, carrageenin- and 5-HT-induced swelling in the feet of rats.(Chen Yi Min, et al. Shanghai Journal of Immunology. 1998;8(5):337.Yu Long Shun, et al. Journal of Chinese Materia Medica. 1989;20(5):221-213.)

 Anti-aging and anti-fatigue effects:

 Fed to D-galactose-modeled senile mice, Tian Ma (4.8g/kg) can significantly recover the subjects' reduced passive avoidance reaction, enhance the activity of SOD in RBC, increase the content of oxyproline in the skin, and reduce lipofuscin in cardiac muscles. The reduction of lipofuscin in the brain and liver, however, is not significant.Research further shows that administered to mice, Tian Ma can decrease HOP in the serum, increase SOD in the blood, and enhance the subjects' swimming endurance.(Gao Nan Nan, et al. Journal of Chinese Materia Medica. 1994;25(10):521-523.Bai Xiu Rong, et al. Journal of Mathematical Medicine. 1996;9(2):180-182.)

 Effects on memory:

 Tian Ma can improve the learning and memory potential of mice that have suffered from cerebral ischemia.Research shows that Tian Ma can significantly promote the proliferation of large gliocytes in rats, enlarge their surface area, and increase their number, thereby supporting learning and memory functions.Tian Ma is also shown to improve the learning and memorizing abilities of senile mice and mice with experimental memory damages.(Du Gui You, et al. China Journal of Chinese Medicine. 1999;24(10):626-628.Liu Jian Xin, et al. China Journal of TCM Theories. 1997;3(6):23-25.Zhou Ben Hong, et al. Journal of Pharmacology and Clinical Application of TCM. 1996;12(3): 32-33.Gao Nan Nan, et al. China Journal of Chinese Medicine. 1995;20(9):562-563.)

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citations1.Description and remedy use of Tall Gastrodia Tuber,Rhizoma Gastrodiae and its Determination Method...

last edit date:15th,June.2009.