What is Chinese FoxGlove Root? How to use a Mountain Cabbage having a root?
Article Content:
- .Basic Botanical Data and Identification of Rehmannia Root.
- .Rehmannia Plant Description.
- .Phytochemicals and constituents of Chinese FoxGlove Root.
- .Edible Uses of Chinese FoxGlove Root,Rehmannia Root.
- .Medicinal Uses and common benefits:Rehmannia Classifications and Main Actions.
- .Actions of Chinese FoxGlove Root,Rehmannia Root.
- .Mechanism of chinese FoxGlove Root,Rehmannia Root:How it Works.
- .Combinations and Application Case Study:Rehmannia Root.
- .Rehmannia Root Suggestions and Administrations.
- .FoxGlove Witchcraft.
- .Rehmannia and Its Relatives.
- .Research Update:Rehmannia glutinosa.
Combinations and Application Case Study:Rehmannia Root.
Combinations of Raw Rehmannia Root:
1. For treating dryness of the mouth with a crimson tongue due to the entry of heat into the blood:
(A) Febrile diseases with such symptoms as coma with high fever and dryness of the mouth with a crimson tongue due to the entry of heat into the blood: It is used with Zhejiang figwort root (Radix Scrophulariae), etc., e.g., Qingying Tang.
(B) Night fever with morning chills and rapid pulse with a red tongue due to unexhausted latent heat and loss of yin fluid in the later stage of a febrile disease:It is used with turtle shell, sweet wormwood (Herba Artemisiae Chinghao), windweed rhizome (Rhizoma Anemarrhenae), etc., e.g., Qinghao Biejia Tang.
2. For treating skin eruption, hematemesis (vomiting of blood) and epistaxis (nosebleed) due to blood heat:
(A) Hematemesis, epistaxis, hemafecia, metrorrhagia and metrostaxis due to blood heat: It is used with fresh lotus leaf, raw Chinese mugwort leaf (Folium Artemisiae Argyi) and oriental arborvitae twig (Cacumen Biotae), e.g., Sisheng Wan.
(B) Hematemesis, epistaxis and dark purple skin eruption due to the entry of heat from a febrile disease into the blood system and exuberant toxic blood-heat:It is used with herbaceous unpeeled peony root (Radix Paeoniae Rubra) and tree peony root-bark.
3. For treating thirst due to impairment of body fluid and diabetes due to interior heat:
(A) Diabetes due to interior heat: It is used with yam, raw milk vetch root (Radix Astragali seu Hedysari) and pig's pancreas, e.g., Zicui Yin.
(B) Constipation with intestinal dryness due to impairment of yin by a febrile disease: It is used with Zhejiang figwort root (Radix Scrophulariae) and ophiopogon root, e.g., Zengye Tang.
Combinations of Prepared Rehmannia Root:
1. For blood deficiency syndrome manifested as pale, dizziness, tinitus, palpitation, insomnia, irregular menstruation:
Prepared Rehmannia Root is often used together with Radix Angelicae Sinensis, Rhizome Ligustici Chuanxiong and Radix Paeoniae Alba to enrich blood and regulate menstruation, as in Decoction of Four Ingredients (Siwu Tang).
2. For yin-deficiency of both the liver and kidney marked by lassitude of the loins and legs, dizziness, tinitus, night sweat, spermatorrhea, fever due to yin-deficiency:
Prepared Rehmannia Root is often used with Rhizoma Dioscorear, Fructus Corni, Cortex Moutan Radicis, Rhizoma Anemarrhenae to nourish yin, replenish kidney, clear away heat and reduce ministerial fire, as in Bolus of Six Herbs Including Rehmannia (Liuwei Dihuang Wan).
Application Case Study of Rehmannia:Shi-Quan-Da-Bu-Tang
Shi-Quan-Da-Bu-Tang (Ten Significant Tonic Decoction), or SQT (Juzentaihoto, TJ-48) was formulated by Taiping Hui-Min Ju (Public Welfare Pharmacy Bureau) in Chinese Song Dynasty in AD 1200. It is prepared by extracting a mixture of ten medical herbs (Rehmannia glutinosa, Paeonia lactiflora, Liqusticum wallichii, Angelica sinesis, Glycyrrhiza uralensis, Poria cocos, Atractylodes macrocephala, Panax ginseng. Astragalus membranaceus and Cinnamomum cassia) that tone the blood and vital energy, and strengthen health and immunity. This potent and popular prescription has traditionally been used against anemia, anorexia, extreme exhaustion, fatigue, kidney and spleen insufficiency and general weakness, particularly after illness. In order to restore immunity in cancer patients, potentiate the therapeutic effect and ameliorate adverse toxicity of anticancer agents, 116 Chinese herbal formularies (Kampo) have been screened and evaluated. Fifteen compounds were found to have such actions. Among these, SQT was selected as the most effective as a potent biological response modifier. During the last eight years, animal models and clinical studies have revealed that SQT demonstrates extremely low toxicity (LD50 > 15 g/kg op murine), self-regulatory and synergistic actions of its components in immunomodulatory and immunopotentiating effects (by stimulating hemopoietic factors and interleukins production in association with NK cells, etc.), potentiates therapeutic activity in chemotherapy (mitomycin, cisplatin, cyclophosphamide and fluorouracil) and radiotherapy, inhibits the recurrence of malignancies, prolongs survival, as well as ameliorate and/or prevents adverse toxicities (GI disturbances such as anorexia, nausea, vomiting, hematotoxicity, immunosuppression, leukopenia, thrombocytopenia, anemia and nephropathy, etc.) of many anticancer drugs. The application and mechanistic studies of SQT in future development have potential importance in basic and clinical research of the traditional Chinese therapeutic approach of "toning the blood and strengthening Qi (vital energy)" in cancer immunotherapy.
Application Recipes Cases from Rehmannia Root:Case 1.Female Regularity Recipe
Female Regularity recipe is made of ginseng, deer horn, carthamus, millettia, notoginseng, common peony root, prepared rehmannia root, Chinese angelica root, atractylodes, wolfberry, scute, cyperus, mother wort, cnidium, de-glued antler powder, donkey hide glue and corydalis.Deficiency of both qi and blood, irregular menses, dkysmenorrhea, sterility.
Modern studies on pharmacodynamics reveal that this product yields actions of activity similar to female sex hormone, remitting the tension of smooth muscle of uterus, analgesia, strengthening the phagocytosis of the organism.
1. Activity similar to female sex hormone:
The method of increasing the weight of female sex organ by estrogen is adopted. Young female rats are used and assigned to experimental and control group. This product is given by gastric perfusion 6000mg/kg. The control group is administered excipient powder in same volume (1 ml) for gastric perfusion. The positive control group is given 4mg of stilbestrol as a reference dissolved in 0.2ml vegetable oil, once every other day for 5 times (10 days). The animals are anatomized 3 days after suspension of the remedy. The weights of ovary and uterus /100g body weight are compared among groups. The weight in the experimental group is 161(mg/100g body weight); the blank control group is 131, the stilbestrol group is 254, with very significant difference among the groups, indicating that this product possesses the activity similar to female sexual hormone. Under the microscope, the endometrium of rat is thickened, with cells arranged evenly in two layers with more acinus in larger volume and near to the endometrium. The acini are in secreting status. In the ovary, there are ova of primary, secondary and mature stages, developed steadily in order. This offers a pharmacological evidence for the action of treating irregular menstruation, underdeveloped sex organs and sterility with this product. It is also evident that, unlike the strong action of stilbestrol, this product demonstrates that the compound recipe of TCM yields persistent and mild actions.
2. Remission of tension of smooth muscle of uterus:
In the solution of this product (1:5) 0.5 ml or 1 ml, the in vitro rat uterus doesn't show tension reaction. After Magnus bath for 5 minutes, 0.125 ipituitrin is added, the uterus contracts. When the medicinal and nutritional solution are removed and the uterus washed, then equal volume of this product (1:5) 1 ml and pituitrin 0.125 are added , the uterus contracts, with a distance 5 mm less than the former one.
3. Analgesia:
One hour before the gastric perfusion administration of this product 0.3g/20g chemical stimulation is given in mice. Aspirin is given for the positive control group in the dose of 180mg/kg, while the blank control group reveals 212 paroxysmal pain within 5 ~10 minutes, being 17.7 in average per mouse. In the aspirin group, there are 81 within 5~10 minutes, being 8.1/mouse. The experimental group reveals 80 in 5~10 minutes, being 8.0/mouse. The inhibition of paroxysmal pain being 50% of the control group, indicating that this product yields marked analgesic effect.
4. Increase of phagocytosis:
This product is prepared as feeding fragments and administered to mice in the dose of 4.8g/kg. The control group is given the same fragments without this product for 7 consecutive days. Then, sterilized broth is injected peritoneally. After 22 hrs, another injection containing chicken RBC suspension 0.5ml /(5,106) is administrated. After 40 minutes, the animals are killed and smears made of abdominal fluid, and stained. Phagocytosis index is determined under the microscope. The control group reveals a phagocytosis rate of 17.32,1.5%, phagocytic index 1.44 ,0.15.That of the experimental group are 32.76,1.80% and 1.50,0.15 respectively, with very significant difference. The phagocytic capacity is markedly increased, but the phagocytic index shows no significant difference.
Clinically, this product was used in menstrual disorders, sterility, and post partal deficiency.
1. Menstrual disorders: Mainly manifesting irregular menstrual cycle, profuse menstrual bleeding, light color and loose texture, lumbago, scanty blood, pink and clear blood like water, or with coagulated clots, leukorrhea, rubrorrhea, phthisis, hectic fever, massive hemorrhage, leaking blood, bloody fainting, bloody collapse, delayed or prior menstruation, menolipsis prior to climacteric period, functional uterine bleeding, uterine bleeding during puberty, climacteric period. This product is indicated for the above disorders.
2. Sterility: This product is indicated for non-organic sterility.
3. Postpartum deficiency: This product is indicated for lassitude after delivery, loss of appetite, insomnia, forgetfulness, lower abdominal pain, and lingering lochia.
Application Recipes Cases from Rehmannia Root:Case 2.Healthy Pregnancy Recipe
Healthy Pregnancy recipes is made of cuscuta seed, amomum fruit, prepared rehmannia root, ginseng, mistletoe, donkey hide gelatin, Chinese cornbind (shou wu), mugwort leaf, morinda, atractylodes, codonopsis, deglued antler powder, wolfberry, dipsacus and eucommia bark.
Chinese uses this time-honored formula to tonify the Qi and blood, promote secretion of ovary hormone, ovulation and conception, maintain healthy functions of the ovary and uterus, nurture the fetus and promote healthy pregnancy.
Chinese Use: Habitual miscarriage, habitual abortion, threatened abortion.
Modern studies on pharmacodynamics reveal that this product yields actions of promoting secretion of ovarian hormone, promoting ovulation, and promoting the growth of ovary and uterus.
1. Promoting secretion of ovarian hormone:.
Female rabbits are randomly assigned to experimental group and control group. The former group is given 27.5g/kg of this product, once daily. For the control group, no medication is given. Other treatments are the same as the experimental group for 26 days. The animals are killed by air emboli on the 13th, 20th, 26th days after medication. Internal sexual organs such as uterus and ovary are taken out for observation of changes under naked eyes and microscope. It can be seen that:
(1) Mild hyperplasic of endometrium, with increased glands, marked secretion, which is increased with the increase of medication days.(secretion is transition from early to late stages ).For the control group , there are less glands ,with proliferation: A few rabbits reveal secretion, but less conspicuous than the test group. Thus, it can be inferred that this product may promote the secretion of luteotrophic hormone, or promote the secretion function of female sex hormone.
(2) The ovary of rabbit in the medication group has more corpus lutcum. Those rabbits receive medication over 21 days have luteum cells distributed over the whole ovary while the control group, had only a certain part of the ovary without corpus hemorrhagicum. The formation and its existence are related to the female sex hormone and pituitary luteotrophic hormone. Thus, it is inferred that this product can promote the level of female sex hormone, or even excite the hypothalamus-pituitary function.
(3)The rabbits in medication group during observation reveal overlapping sexual behavior, but absent in the control group. This overlapping activity is an indication of oestrous period, based on the stimulation of estrogen produced in the ovary, indicating that this product stimulates the ovary to secret estrogen.
2. Promotion of ovulation:
Oral medication of this product is given (dosage 27.5g/kg) for over 21 days. In some individual animals, corpus albicans and corpus hemorrhagicum can be seen which is an indirect indication of ovulation.
3. Promoting the formation and growth of ovary and uterus:
Female rabbit fed with this product (27.5g/kg) for 26 days are examined for its ovary and uterus under the microscope. It can be seen that the rabbits in medication group have richer blood supply to the ovary and uterus than the control group. Since the ovarian blood supply does affect its secretion, therefore, it can be concluded that this product can promote blood circulation through which the metabolism of the ovary and uterus is raised, and as a result their growth are promoted.
Clinically, this product was applied in habitual abortion and threatened abortion.
1. Prevention and treatment of habitual and threatened abortion:
Medication of this product (5g, tid, with 3 months as a therapeutic course, for 1~3 courses, same below), 124 cases were treated, the total effective rate being 94.35%.
2. Sterility:
10 male cases were treated. Among them, 3 cases were impotence, 1 case of non-ejaculation, 6 cases of abnormal seminal fluid. 7 female cases, among them, 2 cases of underdeveloped uterus, 5 cases were dysfunction of corpus luteum and an ovulation .1~3 courses of this product were given (3 months as a course), all cases were cured and fertilized.
Application Recipes Cases from Rehmannia Root:Case 3.Back to Youth Recipe
Back to Youth recipe is made of extracts from prepared rehmannia root, common yam, achyranthes, wolfberry, dogwood fruit, poria, salty eucommia bark, polygala prepared with licorice, roasted morinda, schizandra fruit, salty fennel, chinquapin seed, cistanche, acorus root and common jujube fruit, chinese herbs for aging.
Chinese uses this time-honored formula for its adaptogenic, endocrine regulating and metabolism promoting properties to tonify the heart, kidney, spleen and stomach, help maintain healthy memory power and revive sexual potency, especially among the elderly.
Chinese Use: Hypogonadia, senile dementia.
Modern studies on pharmacodynamic reveal that this product yields actions of anti-senility, regulating endocrine secretion, promoting organic metabolism, stimulating immunity, protecting the liver and detoxication, tolerating anoxia, and sedation.
1. Anti-senility:
The alcohol extract of this product markedly prolongs the average life and highest life time of drosophila, indicating its anti-senility action.
2. Regulating endocrine secretion:
(1)Action similar to androgen: castrated young male mice are administered this product 10g/kg, q.d. for 21 consecutive days. The weight of its seminal vesicle can be greatly increased.
(2)Stimulating the function of adrenal cortex: by evaluating the content of adrenal cortical hormone in mice, it can be proved that the contents of cortisone in the plasma in mice can be increased by this product.
(3)Effect on model of deficient kidney yang induced by "hydro-cortisone": This product can protect, to certain extent, the failure of adrenal cortical function in mice induced by massive dose of hydro-cortisone (i.m. 1.0mg/day for 10 consecutive days.)
3. Promoting organic metabolism:
This product promotes the infiltration of 3H-TdR, 3H-UR and 3H-Leu into the DNA and RNA in mice liver, indicating that it promotes the nucleic acid metabolism and protein synthesis.
4. Stimulating immunity:
This product can activate the phagocytosis of abdominal macrophage in mice, and markedly increase the T-cell in 615 mice as compared with the control group, indicating that it excites the immunity.
5. Adaptogenoid action.
(1) Protecting the liver and detoxifying action: This product markedly lowers the mortality of mice due to CCl4 intoxication as compared with the CCl4 model group, thus inferring that it may yield certain antagonistic action on the peroxidation of facts due to CCl4, or, in other words, it yields some protection on the injury caused by the free radicals. This is beneficial to the delay of advent of senility.
(2) Tolerance to anoxia: This product markedly increases the tolerance to anoxia under regular atmospheric pressure in mice.
Toxicological studies: after perfused with the maximal amount of this product in a dose of 40g/kg in mice, no abnormal reaction or death can be seen, indicating its low toxicity. When perfuse this product in the doses of 4,8,16g/kg for 6 consecutive months, no obvious reaction can be seen in its growth, appetite, blood picture, EKG, hepatic and renal functions.
Clinically, this product was applied in hyposexuality, and senile dementia.
1. Hyposexuality:
by adopting double blind method with anxiyong as control, this product was tested clinically with a dose of 6 capsules t.i.d for 3 consecutive months, 61 cases of deficient kidney-yang in senile and middle-aged patients were treated (30 cases were in the control group). After treatment, symptoms in the treatment group were markedly ameliorated. Among them, marked improvements were seen in chillness, cold limbs, sour waist and knee, nocturnal urination, loose stool, hypo-sexual desire, lassitude, white hairs, forgetfulness. This product also yielded actions of reinforcing the holding strength, decreasing the width of senile circle, improving scores of psychic senility, strengthening immediate memory and increasing the time of standing with a single foot. The total analysis showed the total effective rate to be 74.2%, while that for the control group, 30%, indicating that this product yielded better therapeutic effect on anti-senility and deficient kidney yang syndrome.
2. Senile dementia:
Decoction of this product was given once daily with 3 weeks as a therapeutic course. The patients ranged from 65~75, evidenced by cerebral atrophy under CT, cerebral malacia. After 3 weeks of treatment, 5 cases were cured; 4 cases, markedly improved; 3 cases, improved; 2 cases, ineffective.
Application Recipes Cases from Rehmannia Root:Case 4.Eye Sight Recipe
The Eye Sight recipes is made of extracts from wolfberry, chrysanthemum flower, prepared rehmannia root, dogwood fruit, moutan bark root, common yam, poria and alisma, this time-honored formula is used in Chinese medicine for its immune supporting, and other properties to nourish the liver and kidney and to maintain healthy eyesight.
Chinese Use: Central retinitis, glaucoma, senile cataract, neuropapillitis, cerebral concussion sequelae, hypertension, chronic hepatitis.
Modern studies on Pharmacodynamical reveal that this product yields actions of strengthening the immunity and anti-senility.
1. Promotion of immunity:
200% Decoction of this product is administered to young mice by gastric perfusion in a dose 60g/kg daily for 2 consecutive weeks. The positive percentage of acidic ANAE lymphocytes in peripheral blood and the number PFC of the spleen are all markedly higher than that in the control group, demonstrating that this product yields an effect of strengthening the function of T, B- lymphocyte. By adopting the receptor tests of EA rosette (Fc receptor) and YC rosette (C3b receptor) exams, it is demonstrated that this product also markedly strengthens the function of abdominal macrophage C3b receptor in young mice, but yields little effect on the Fc receptor, demonstrating that this product possesses multifacet function for strengthening the immunity; its mechanism of action may be optional.
2. Anti-senility:
200% Decoction of this product is given by gastric perfusion to senile mice in a dose 60g/kg daily for 2 successive weeks. The peripheral blood positive ANAE lymphocyte percentage is markedly elevated, and even exceeding that of the young control group. It also markedly promotes the PFC, and markedly recovers the senilized immunity in senile mice, demonstrating that this product yields certain anti-senilily action.
Clinically, this product was applied in central retinitis, glaucoma, papillitis, sequelae of cerebral concussion, hypertension, and chronic hepatitis.
1. Eye diseases:
Modification of this product was applied to treat 140 cases of old retinitis for 9 weeks, 22 cases were cured; 21 cases, markedly effective; 70 cases, ameliorated; the total effective rate being 80.27%. When this product was used with Rhizoma Dioscorea excluded and Radix Angelica sinensis, Radix Salviae miltiorrhigae, Lignum Sappan added for a case of central retinitis of the type of yin deficiency of liver-kidney, with asthenic fire flaring upward for 3 months. The eyesight was totally recovered from 0.2 and 0.8 before treatment to 0.9 and 1.5 after the treatment. A case of glaucoma was treated with modification of this product for over 1 months, the eyesight was also recovered completely. Another case of sudden blindness due to fundal bleeding was treated with over 20 doses of this decoction, the bleeding was absorbed and vision recovered. 21 cases (32 eyes) of degeneration of macula lutea were treated with oral solution of this product, with another 19 cases (32 eyes) administrated with Vit. E (0.1g, t.i.d.) as control for 4 months. Results showed that the symptoms vanished in 14 eyes (43.8%) in the treatment group; that of the control group, 5 eyes (15.6%). Amster test in the treatment group revealed that 12 eyes out of the 18 abnormal eyes recovered to normal, while only 5 out of the 16 abnormal eyes in the control group recovered. For eyesight, 20 eyes in the treatment group recovered. (Increase of 2 lines as compared with the original vision), representing 62.5%, vision in 5 eyes (15.6%) was aggravated. While in the control group, the results being 4 eyes (12.5%) and 12 eyes (37.5%) respectively.
2. Sequelae of cerebral contusion:
12 cases were treated with modification of this product for an average of 12.5 doses. 9 cases were cured for short-term, 1 case ameliorated, the total effective rate being 83.3%.
3. Chronic viral hepatitis:
32 cases were treated (18 were active cases, 14 delayed chronic cases, all liver protection agents were interrupted), one pill, b.i.d. for the 10 cases in the control group were administered granules one package, t.i.d. and 3 tablets t.i.d. for 3 months as a course. After 1~2 course of treatment, 23 cases in the treatment group had symptoms basically vanished; 7 cases, ameliorated; 2 cases remained unchanged; the total effective rate being 93.8%. 12 cases had the size of liver shrunk to normal. 2 cases had spleen size returned to normal. The results in the control group revealed that 1 case had symptoms basically disappeared, 5 cases ameliorated, 4 cases unchanged, the total effective rate being 60%. 1 case had liver size turned to normal. The long-term effect of this product is also superior to the control group.
4. Hypertension:
16 cases of primary hypertension of deficient kidney yin type (I stage) were treated with this product for 8~12 weeks. The clinical symptoms were markedly ameliorated, with marked lowering of the score for 7 symptoms.
Application Recipes Cases from Rehmannia Root:Case 5.Blood Circulator Recipe
Blood Circulator Made of medicinal rhubarb, prepared rehmannia root, common peony root, peach seed, bitter apricot seed, licorice root, scute, dun fly, gadfly, leech, June beetle grub, dried lacquer and ground beetle
Chinese medicine uses this time-honored formula to promote micro-circulation, increase blood flow to heart muscles, open and clear arteries, inhibit intestinal adhesion, soothe the liver, remove stasis and maintain healthy blood circulation and regular menses.Chronic hepatitis, hepatocirrhosis, hypertension, cerebral thrombosis, aplastic anemia, chronic leukemia, varicosity complication and sequelae, and surgical, gynopathic and dermopathic diseases.
Modern studies on pharmacodynamics reveal that this product yields action of improving micro-circulation, increasing myocardial blood flow, lowering blood viscosity, anti-thrombosis and inhibiting platelet aggregation, anti-atherosclerosis, preventing and treating intestinal adhesion, and protecting chronic liver injury.
1. Improvement of micro-circulation:
This product is perfused to the stomach of rat of blood stasis model induced by metamethasone for 7 consecutive days. The symptoms are markedly ameliorated, the flowing status of blood stream is mainly on particle or line stream, the number of open capillaries is increased with greater calibre, RBC aggregation and its adhesion to the vessel wall in the capillary loops also decreased, indicating that this product markedly improves the microcirculation in blood stasis animal model.
2. Increasing myocardial blood flow:
Experiments show that, in cardiac ischemic mice induced by pituitrin and in normal mice, this product dilates coronary arteries, improves myocardiac microcirculation, markedly increases the nutritional blood flow to ischemic myocardium in mice and normal mice.
3. Lowering blood viscosity, shortening the time of electrophorasis:
When rat is given 13g/kg (i.g.) for 4 consecutive days, the viscosity of whole blood and plasma is decreased in blood static model induced by adrenalin. Time of cellular electrophoresis is shortened, and the Evans blue content in the arterial wall is markedly lowered.
4. Anti-thrombosis and inhibiting platelet aggregation:
Experiment on rats, both in vivo and in vitro, show marked inhibitive action on hemostasis induced by ADP, and decreasing in adhesion and aggregation of platelets.
5. Anti-atherosclerosis:
This product markedly lowers the TG and TC in both hyperlipidemia patients and experimental hyperlipidemia partridges, the size of plaques in these experimental animals are reduced and vanished fast.
6. Preventing and treating intestinal adhesion:
Gastric perfusion with suspension of this product is given to intestinal adhesion rat induced by clamping the intestines, resulting in great amelioration of the adhesion. When administrated to dogs or mice, the intestinal in vivo can be mildly and persistently strengthened.
7. Protecting chronic liver injury:
This product can mitigate the formation and progress of chronic hepatic lesion in rat induced by CCL4 and ethyl alcohol. It inhibits fibrosis and proliferation of fibers. In addition, it also eliminates the immune compound material precipitated in the liver, increases the immunity, turns the HbsAg negative.
Clinically, this product is applied in chronic active hepatitis, hypertension, liver cirrhosis, cerebral thrombosis, aplastic anemia, chronic leukemia, complications and sequelae of varicose veins, and other diseases in surgery, gynecology, dermatology and neurology.
1. Chronic active hepatitis and liver cirrhosis:
This product was given 1 pill three times daily for 2 months to one year. 40 cases were treated, 22 cases were cured; 12 cases, effective; 4 cases non-effective; the total effective rate being 90%. All symptoms (lassitude, abdominal distension, poor appetite etc.) were ameliorated or vanished, jaundia disappeared, splenomegaly and hepatomegaly decreased, and liver function markedly improved. In 70% cases sGPT returned to normal, in 64.5% cases icterus index and bilirubin returned to normal. 50 cases of cirrhosis with ascitis were treated with concerted with Liujunzi Decoction, 22 cases were markedly effective; 22 effective. After medication, ascites disappeared, half of them with enlarged spleen and liver returned to the normal size.
2. Hypertension and cerebral thrombosis:
34 cases were treated with this product (modified): one week after medication, the condition begun to mitigate; the paralyzed body parts begun to recover, reaching to its peak effect at the sixth week. 25 cases were clinically cured; 6 cases, markedly effective; 2, effective; 1 cases non-effective.
3. Lung cancer, liver cancer:
62 cases of primary lung carcinoma were treated plus Rhizome Sparganii and Rhizome Zedoariae, 4 cases were markedly effective; 34, effective; 2, survived over 3 years; 2, survived over 2 years; 1, 1 year.
4. Aplastic anemia and chronic leukemia:
16 cases of chronic granulocytic leukemia were treated. After medication, the spleen decreased in size to some extent, of these, 65.5% were markedly decreased, the total effective rate being 87.5%, 1 case, dead; 20 cases treated with myleran alone was inferior to the above group. Indicating this product is helpful as an adjuvant remedy. A case of primary thrombocytopenic purpura, manifesting purpura in the skin, with teeth bleeding, lassitude, vertigo for 5 years, platelet count 62-88X109/L. After 80 doses were given, the platelet increased to 124X109/L. Then honey bolus of this product was administrated 10g daily in two times for one year, the platelet count raised to112-76X109/L. No more bleeding occurred.
5. Others:
19 cases of varicose veins with complications and sequelae were treated with satisfactory results. Modified recipe of this product also applied in high blood viscosity, chlecystitis, hepatic cyst, ovarian cyst, myoma of uterus, intestinal adhesion, polyphagia, chronic glomerulo-nephritis, rheumatoid arthritis, cervical tubereulous lymphadenitis, tuberculous peritonitis, severe chloasma, all with satisfactory results.
Application Recipes Cases from Rehmannia Root:Case 6.Leak Control, Incontinence Treatment Recipe
Leak Control, Incontinence Treatment, is made from a time-honored formula of extracts. This Incontinence Treatment is made from prepared rehmannia root, fried common yam, Chinese angelica root, cinnamon bark, prepared aconite, lindera root, wolfberry fruit, prepared Chinese dodder seed, eucommia bark in ginger, fried antler glue, Asiatic cornus fruit, alpinia fruit, manitis egg case and Chinese leek seed.
Chinese uses it to strengthen the urinary muscles and enhance urine witholding power providing help with incontinence.Chinese Use: urinary incontenence, impotence, urine control. Leak Control, Incontinence Treatment Recipe yields actions of strengthening immunity, protecting and regulating visceral functions. Anti-senility. Regulating the content of hormones, inhibition of electric discharge.
1. Strengthening of organic immunity:
This pill partially antagonizes the hormone action on splenic lymphocytes, and mild action on thymus lymphocytes, markedly increase of hemolytic plaque, prolongation of in vitro survival rate of splenic cells, demonstrating that this pill can improve and adjust B-cell function and promote humoral immunity.
2. Protection and regulation on important organs in experimental "deficient yang":
(1) increase the weight of organs; (2) protect the sub-micro structure of liver cellular nuclei, increase the content of RNA and glucose-b-de-phospho-dehydrogenase, hence, regulate the DNA, RNA and protein synthesis;(3) protect the splenic lymphocyte; (4) mildly in crease the nonspecific esterase of adrenalin.
3. Regulating the content of sex hormone:
It increases the lowered content of serum androgen in deficient yang men, and lowers its content to normal range in those men with elevated androgen. While it yields no action to serum androgen in women whose kidney yang is deficient, but it regulates their lowered estradiol to normal, demonstrating that the mechanism of Yougui Pill is different from exogenic sex hormone, it mainly improves the body function,restores the hormonal secretion of hypothalamus-pituitary-gonad system.
4. Anti-senility:
(1) lowers the hydroxyproline of kidney in senile mice, and also lowers its content to the level of middle-aged in senile rat, demonstrating its delayed action on the senility of the heart and kidney.
Clinical studies Yougui Pill was applied in hyposexuality, osteoporosis, chronic bronchitis, Sciatica with the following results:
1. Hyposexuality:
11 cases were administered with this product for 2-3 consecutive months, 45.5% of the cases had sexual function recovered, 83.3% recovered after medication of 2-4 months.
2. Osteoporosis:
52 senile cases were treated. After 6-8 months of medication signs, symptoms, end X-ray changes in bone trabeculi were used for score evaluation of effect: Results showed that 42 cases (80.8%). Were markedly effective; 8 (15.4%), effective; 2 cases, ineffective, the total effective rate being 96.2%.
3. Chronic bronchitis:
53 cases were treated. Results showed that 84.9% had conditions stable or basically stable; 6 Cases, ameliorated; 2 cases, ineffective; the total effective rate being 96.2%.
4. Sciatica:
48 cases were treated. Among them, 66.7% were cured; 91.7%, effective. 1. Frequent micturation: markedly decreased this volume of urine and micturation frequency.
5.Enuresis:
15 cases were treated, 11 cases were cured, 4 ameliorated after 20-40 doses of medication.
Application Recipes Cases from Rehmannia Root:Case 7.Hair Regeneration Recipe
Hair Regeneration is made with exracts from prepared rehmannia, Chinese angelica (dong quai), notopterygium, Chinese quince, cnidium, common peony root, dodder, gastrodia and prepared Chinese cornbind (shou wu).This time-honored Hair Regeneration formula is used in Chinese medicine to nourish the blood and supplement the kidney, inhibit bacteria, ease itching and to promote healthy hair growth and prevent hair loss.
1. Effect on thymus, adrenal gland, sex gland and acidophilic leucocytes count:
Experiment show that this product can strengthen ACTH's action on adrenals (weight increased) and thymus (atrophied), while no obvious decrease of acidophilic leucocyte is observed.
2. Anti-aging:
In recent years, it has been found that the existence of SOD is closely related to the aging process. When organism is getting older, SOD lowers markedly. It has been approved in mice that as age is progressing, the SOD content in blood lowers. By feeding mice with Radix Polygoni multiflori, its SOD content increases after several months, indicating that it affects SOD, and is beneficial to anti-senility.
3. Bacteriostatic action:
In In vitro antibacterial experiments, water extract of Radix Polygoni multiflori (prepared in different ways) shows antibacterial action to different extent on staphylococcus aureus and staphylococcus albus.
Clinically, this product is used in alopecia due to blood deficiency and kidney deficiency: It is reported that 117 cases were treated with this product for 15-60 days. 83 cases were cured; 18 cases, ameliorated; 16 cases non-effective, the total effective rate being 86.3%
Application Recipes Cases from Rehmannia Root:Case 8.Spermarize Male Fertility Recipe
Spermarize Male Fertility Recipe has been developed and used in China to increase male sperm count and the mobility of human sperm. Spermarize includes ingredients that have been studied in China for their ability to enhance sperm count and mobility in order to enhance fertility during copulation.
According to the publication, Scientific Data of Chinese Herbal Medicine,Spermarize Male Fertility Recipee is an effective herbal formulation for Male Infertility. The article states, that since 1991, 300 male patients have been treated with Spermarize with a total effective rate of 93.33% in the test group. Further tests, also in China, show no side effects or toxicity in doses 170 times greater than the normal human dose.
The combination included: Shorthomed Epimedium herb (Horny Goat Weed),Prepared Rehmannia root (Chinese Foxglove),Barbary Wolfberry fruit (Fructus Lycii, Gou Qi Zi),Chinese angelica (Radix Angelicae Sinensis),Licorice root (Radix Glycyrrhizae),Dipsacus root (Radix Dipsaci),Chinese Magnolcavine fruit (Schisandra chinensis),Plantain seed (Semen plantaginis, Che qian zi),Cornu Cervi Pantotrichum (Lurong, Pilose antler, Pilose deer horn).
Application Recipes Cases from Rehmannia Root:Case 9.Super Male Libido Enhancement Recipe
This time-honored Male Libido Enhancement formula is made of extracts from prepared rehmannia root, fried common yam, wolfberry fruit, prepared Chinese dodder seed, eucommia bark in giner, freid antler glue, Asiatic cornus fruit, Chinese angelica root, cinnamon bark, prepared aconite, lindera root, alpinia fruit, mantis egg case and Chinese leek seed. Chinese medicine uses it to strengthen the kidney and as a natural herbal remedy to increase erection and withholding power for a man, and to increase sperm count.
Reference:
1.What is Chinese FoxGlove Root? How to use a Mountain Cabbage having a root?
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