Babchi seeds or Psoralea corylifolia,very useful phytochemicals in the future.

Pharmacology Study of Psoralea corylifolia seed.

Psoralea fruit Extract INCI Name Psoralea Corylifolia Extract Babchi seed extract Psoralen CAS 10523-56-5 isopsoralen CAS 523-50-2 photo picture image Pharmacology of Psoralen(C₁₁H₆O₃):

Pigmented deposit: Oral taken by rabbit at dose 4 mg/g,exposed in sun of rabbit back skin,pigment deposit occurs.Reference:Modern Study of TCM and Clinical Applications,by Yin Jian,etc.Xue Yuan Publishing,Beijing,1993,382.

Anti-Cancer and Boost Immune System: Black light 250 ug/ml,shows strong killing effects on mice osteosarcoma cell S₁₈₀,MTT method shows:relative anti-tumor activity index of proralen for mucoepidermoid carcinoma cells(IC₅₀: 8.6ug/ml): 15;MTT method shows psoralen release stronger kill effects on leukaemia,when dosage lower than 8 ug/ml,the kill capacity decreased;Intraperitoneal injection 1 time daily 0.2 ml dose to mice,10 days period,inhibition ratio of transplanted tumor as :S₁₈₀:40.2%;EAC:68.0%;H₂₂:20.5%;apply Ethyl Carbamate to induce lung tumor of mice,dose 1 mg/ml(contains psoralen and isopsoralen),strong immune boost effects got.Reference:Shaan Xi Zhong Yi,1990,11(9):427,by Zhao Jianbing,etc.Shi Yong Kou Qiang Yi Xue Za Zhi,1990,6(4):320;by Wu Junzheng,etc.Zhong Xi Yi Jie He Za Zhi,1990,10(6):370;by Lu Zehua,etc.Shaan Xi Xin Yi Yao,1983,(10):49,by Yang Yi Can,etc.Zhong Xi Yi Jie He Za Zhi,1989,(1)2:736,by Yang Yican,etc.

Anti-Bacteria: Black light 0.5 ug,shows strong inhibition on bacteria such as:Microsporum Canis,Microsporum gypseum,microsporum ferrugineum,Trichophyton rubrum,Trichophyton mentagrophytes,Staphylococcus aureus,Candida albicans,Group B Streptococcus,E.coli,Pseudomonas aeruginosa,etc.

Effects on Blood System: Stanch effects on uterus,bleeding of uterus,nose and gum,diastolic function of Bronchial Smooth Muscle proved.

Heart Effect: Expand coronary vessels of isolated rabbit heart,Posterior Pituitrin induced coronary artery shrink,boost and strong the heart shrink capacity.

Sleep Effect: Extending sleeping of mice induced by Pentobarbital Sodium and Barbital sodium.

Effect on medicine metabolism: Increase liver microsome protein concentration,thus increase concentration of P-250 and NADPH-cytochrome C.

Pharmacology of Isopsoralen(C₁₁H₆O₃):

Pigmented deposit: Pigmented deposit proved,but weaker than psoralen,prompt re-birth of skin pigmented mole.

Anti-Early Pregnant Effects: Anti-Early Pregnant experiment shows that 10 mg injection to mice uterus released strong anti-early pregnant effects.

Anti skin transplantation Rejection: Dose 2.0 mg/capsule to rabbit ,1 caps daily,black light 2 hours later,20~30 days,Anti skin transplantation Rejection effects proved.

Reference:

1.Babchi seeds or Psoralea corylifolia,very useful phytochemicals in the future.

last edit date:8th,Mar.2010.

Available Product

Name:Psoralea fruit Extract
Serie No:R101.
Specifications:10:1 TLC
INCI Name:PSORALEA CORYLIFOLIA EXTRACT
EINECS/ELINCS No.:N/A
CAS:N/A
Chem/IUPAC Name:Psoralea Corylifolia Extract is an extract of the fruits and seeds of the psoralea,Psoralea corylifolia,Leguminosae

Supplying Conditions