Babchi seeds or Psoralea corylifolia,very useful phytochemicals in the future.

Administration and Suggestion.

Psoralea fruit Extract INCI Name Psoralea Corylifolia Extract Babchi seed extract Psoralen CAS 10523-56-5 isopsoralen CAS 523-50-2 photo picture image Dosage Suggestions:

Seed powder: 1 - 2 gms b.i.d.Seed oil : topical use

Psoralea Safety and Interaction Information:Psoralea is generally regarded as safe; however, if this herb is being used to treat a light-sensitive disorder, it is important to use sunscreen or avoid sun exposure. It is possible to experience skin irritation and blistering when using this herb topically. If that happens, discontinue use. There have also been occasional side effects such mild stomach upset, but taking ginger tea usually resolves the problem. If not, discontinue use.
Interactions:Do not use Psoralea with licorice root.

Toxicity Study:

Acute Toxicity:Psoralen

LD₅₀.Lethal dose,50 percent kill,Oral.Mice.625 mg/kg.
LD₅₀,Lethal dose,50 percent kill,Subcutaneous injection.Mice.480 mg/kg.

LD₅₀.Lethal dose,50 percent kill,Oral..Rat.1330 mg/kg.

LD₅₀,Lethal dose,50 percent kill,Subcutaneous injection.Rat.830 mg/kg.Reference:Zhong Yao Da Ci Dian(TCM Big Dictionary),by Jiang Su Xin Yi Xue Yuan,Shang Hai Science and Technology Publishing.1986.1177.

Mutagenic Data:Psoralen

Mutation in microorganisms.Bacteria-Salmonella typhimurium,16500 ug/L.Reference:JOBAAY Journal of Bacteriology.(American Soc. for Microbiology,1913 I St.,NW,Washington,DC 20006)V.1-1916-Volume(issue)/page/year:121,259,1975.

Mutation in microorganisms.Bacteria-Escherichia coli.20 mg/L.Reference:MUREAV Mutation Research.(Elsevier Science Pub.B.V.,POB 211,1000AE Amsterdam,Netherlands)V.1-1964-Volume(issue)/page/year:58,23,1978.

DNA Damage.Bacteria-Escherichia coli;1700 ng/L.Reference:JMOBAK Journal of Molecular Biology.(Academic Press,Inc.,1 E.First St.,Buluth,MN 55802)V.1-1959-Volume(issue)/page/year:103,39,1976.
Mutation in microorganisms.Yeast-Saccharomyces cerevisiae.50 umol/L.

Gene conversion and mitotic recombination.Yeast-Saccharomyces cerevisiae.50 umol/L.Reference:BUCABS Bulletin du Cancer.(SPPIF,B.P.22,F-41353 Vineuil,France)V.53-1966-Volume(issue)/page/year:67,245,1980.

Data in USA:Psoralen

EPA GENETOX PROGRAM 1988,Positive:In vitro mammalian nonhuman micronucleus.
EPA GENETOX PROGRAM 1988,Inconclusive:S cerevisiae-reversion.

Acute Toxicity:Isopsoralen

LD₅₀.Lethal dose,50 percent kill,Intramuscular injection.Mice.180+-29.6 mg/kg.
LD₅₀,Lethal dose,50 percent kill,Intraperitoneal injection .Mice.138.0+-10.9 mg/kg.Reference:Zhong Yi Yan Jiu Yuan Zhong Yao Yan Jiu Suo Ji Hua Sheng Yu Yan Jiu Shi.Zhong Yao Yan Jiu Zi Liao,1979,(1):16.

Reference:

1.Babchi seeds or Psoralea corylifolia,very useful phytochemicals in the future.

last edit date:8th,Mar.2010.

Available Product

Name:Psoralea fruit Extract
Serie No:R101.
Specifications:10:1 TLC
INCI Name:PSORALEA CORYLIFOLIA EXTRACT
EINECS/ELINCS No.:N/A
CAS:N/A
Chem/IUPAC Name:Psoralea Corylifolia Extract is an extract of the fruits and seeds of the psoralea,Psoralea corylifolia,Leguminosae

Supplying Conditions