Oligomeric Proanthocyanidins,OPCs:Introduction and Its Benefit Applications.

Oligomeric Proanthocyanidins Safety and Toxicity.

Oligomeric Proanthocyanidins OPCs INCI Name Vitis Vinifera Seed Extract CAS 84929-27-1 EINECS ELINCS No 284-511-6 glycosidic anthocyanidins,monomeric flavan-3-ol catechins and flavan-3,4-diol units,antioxidants,free radical scavengers photo picture image Acute toxicity(LD50):Grape Seed Extract.OPCs:
LD50-Lethal dose,50 percent kill.Oral.Rodent-mouse.>4000 mg/kg.
LD50-Lethal dose,50 percent kill.Oral.Rodent-rat.>4000 mg/kg.

Chronic toxicity:Grape Seed Extract.OPCs:
Chronic toxicity test.Oral.Dogs.Dose/Period:60 mg/kg/day.12 Months.No toxic effects.
Chronic toxicity test.Oral.Rats.Dose/Period:60 mg/kg/day.6 Months.No toxic effects.

Proanthocyanidins are almost completely non-toxic both in acute dosage (LD50>4,000 mg/kg in rats and mice) and high long-term dosage (no toxic effects at 60 mg/kg/day for 12 months in dogs and six months in rats). They have no potential for causing mutations or birth defects, and have no adverse effect on fertility, pregnancy, or nursing.

Reference:

1.Oligomeric Proanthocyanidins,OPCs:Introduction and Its Benefit Applications.

last edit date:11th,Mar.2010.

Available Product

Name:Oligomeric Proanthocyanidins:OPCs.
Serie No:Pure01.
Specifications:98%UV-VIS.
INCI Name:VITIS VINIFERA SEED EXTRACT
EINECS/ELINCS No.:284-511-6
CAS:84929-27-1
Chem/IUPAC Name:Vitis Vinifera Seed Extract is an extract of the seeds of the grape,Vitis vinifera,Vitaceae

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