Resveratrol:Trans-3,5,4'-trihydroxystilbene.:Introduction and Its Benefit Applications.

Introduction:Resveratrol.

Resveratrol:Trans-3,5,4'-trihydroxystilbene CAS:501-36-0 trans.61434-67-1.cis transresveratrol flavonoids,Phytoestrogen,Antioxidant,Anticancer,Antitoxic photo picture image Trans-Resveratrol is a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 uM, respectively; with essentially no inhibition of the COX activity of COX-2. It also has antioxidant properties. Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity.

Resveratrol (trans-3,5,4'-trihydroxystilbene), a compound found largely in the skins of red grapes,an oriental medicine used to treat diseases of the blood vessels, heart, and liver. It came to scientific attention only a few years ago, however, as a possible explanation for the "French Paradox" -- the low incidence of heart disease among the French people, who eat a relatively high-fat diet. Today, it is touted by manufacturers and being examined by scientific researchers as an antioxidant, an anti-cancer agent, and a phytoestrogen.
Resveratrol:Trans-3,5,4'-trihydroxystilbene CAS:501-36-0 trans.61434-67-1.cis transresveratrol flavonoids,Phytoestrogen,Antioxidant,Anticancer,Antitoxic photo picture image

The four stilbenes cis- and trans-resveratrol, and their glucosides cis- and trans-piceid are sometimes analyzed together as a group.

Resveratrol (trans-resveratrol) is a phytoalexin produced naturally by several plants when under attack by pathogens such as bacteria or fungi. Resveratrol has also been produced by chemical synthesis and is sold as a nutritional supplement derived primarily from Polygonum Caspidatum Root. Resveratrol is found in the skin of red grapes and is a constituent of red wine, but apparently not in sufficient amounts to explain the French paradox. Experiments have shown that resveratrol treatment extended the life of fruit flies, nematode worms and short living fish but it did not increase the life span of mice.

In mouse and rat experiments, anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects of resveratrol have been reported. Most of these results have yet to be replicated in humans. In the only positive human trial, extremely high doses (3~5 g) of resveratrol in a proprietary formulation have been necessary to significantly lower blood sugar.