Ursolic acid:(3Beta)-3-hydroxyurs-12-en-28-oic acid.:Introduction and Its Benefit Applications.
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Introduction:Ursolic acid.:
Ursolic acid is a pentacyclic triterpene acid, used in cosmetics, that is also capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor.
Ursolic acid is also known as Prunol, Malol, Urson, beta-Ursolic acid, NSC4060, CCRIS 7123, CHEBI:9908, TOS-BB-0966, and 3beta-Hydroxyurs-12-en-28-oic acid. As medicine it is well tolerated and can be used topically and orally.A pentacyclic terpene that crystallizes from absolute alcohol solution, found in leaves and berries of plants; used in pharmaceutical and food industries as an emulsifying agent.
Ursolic acid is present in many plants, including apples, basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, prunes. Apple peels contain high quantity of ursolic acid and related compounds which are responsible for the anti-cancer activity of apple. Ursolic acid can also serve as a starting material for synthesis of more potent bioactive derivatives, such as anti-tumor agents.
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- 1.Ursolic acid:(3Beta)-3-hydroxyurs-12-en-28-oic acid.:Introduction and Its Benefit Applications.
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