Ursolic acid:(3Beta)-3-hydroxyurs-12-en-28-oic acid.:Introduction and Its Benefit Applications.
Contents
Ursolic acid Safety and Toxicity.:
Acute toxicity (LD50):Ursolic acid
LD50-Lethal dose,50 percent death.Intraperitoneal.Rodent-mouse >637mg/kg.LD50-Lethal dose,50 percent death.Oral.Rodent-mouse.8.33grams(8330 mg)/kg.
Chronic toxicity:Ursolic acid
Hypodermic Injection:Rodent-mouse.3500mg/kg.No Death in 72 hours.
Hypodermic Injection:Rodent-Rat.Dose/Period:0.5 gram/kg.30days.No distinctive effect on body weight, blood, cardiogram, liver,and kidney functions. No pathology changes for important organs,result prove ursolic acid low toxicity and safe enough.
Reference:
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- 1.Ursolic acid:(3Beta)-3-hydroxyurs-12-en-28-oic acid.:Introduction and Its Benefit Applications.
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