Feverfew,Dioscorides's Fever Reducer or febrifugia,what is the history of this pretty daisy-like flower?
Contents
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- Basic Botanical Data of Feverfew.
- Cultivation of FeverFew:Feverfew Related Species.
- Feverfew History.
- Phytochemicals and Constituents.
- How FeverFew works in the body and Mechanism.
- Medicinal Action and Uses.
- Modern interest of Tanacetum parthenium.
- Modern Research Update.
- FAQ:Frequently Asked Questions of FeverFew.
- Feverfew:Identification by HPTLC Fingerprint.
- Research Update:FeverFew or Tanacetum parthenium.
Modern Research Update.:
Preventing migraine headaches:
When the wife of a Welsh doctor ended her 50-year-old history of migraine with a course of feverfew, a detailed scientific investigation of feverfew got underway, and in clinical trials in Britain during the 1980s feverfew was demonstrated to be an effective remedy for migraine. Despite extensive research, the exact nature of its action is not yet understood, but the constituent parthenolide appears to inhibit the release of the hormone serotonin, which is thought to trigger migraine.
"Feverfew taken prophylactically prevents attacks of migraine."
Has demonstrated in randomized, double-blind, placebo-controlled clinical trials a reduction in the mean number and severity of migraine attacks and in the degree of vomiting; duration of individual attacks was unaltered. There were no serious side-effects.
Found to be beneficial in migraine prophylaxis as an additive drug during long-term clinical studies in migraine clinics.
A migraine is a severe headache that can last for a day or more with symptoms including pain in the forehead, left or right temples, and is often accompanied by nausea and sensitivity to light. Migraines are classified as with or without "aura," a type of visual disturbance. Successful alternative non-drug treatments include riboflavin (vitamin B2), coenzyme Q10 (CoQ10), feverfew (Tanacetum parthenium), and magnesium. These dietary supplements support nervous-system health and can be part of an effective long-term migraine prevention strategy.
According to a three-month double-blind study of 55 migraine sufferers, those who took 400 mg of vitamin B2 per day reported 68% fewer migraine attacks and, when migraines did occur, shorter episodes of pain compared to placebo. Experts usually recommend taking vitamin B2 along with the rest of the vitamin B complex.
In a three-month double-blind trial of 42 migraine sufferers, those who took 300 mg of CoQ10 per day,in three 100 mg doses,reported less nausea, and just 3.2 migraine attacks per month; down from 4.4 monthly migraine attacks prior to treatment. The placebo group reported no change in migraine frequency or in days of nausea.
In an eight-month double-blind trial of 59 migraine sufferers, about half took a 50 mg capsule of powdered feverfew leaf twice per day for four months, while the others took a placebo. At the midway point in the trial, the groups switched treatment and placebo, and continued for four more months. Overall, those who took feverfew reported an average of 24% fewer migraines, and a decrease in nausea and vomiting during headache episodes, while the placebo groups reported no relief.
Researchers believe that migraine sufferers generally have low body stores of magnesium. In a 12-week trial, 81 migraine sufferers took either 600 mg of magnesium per day or a placebo. After nine weeks, the treatment group reported 41.6% fewer migraines compared with just 15.8% of those in the placebo group.
Rheumatoid arthritis:Feverfew's effectiveness in the treatment of rheumatoid arthritis is being investigated:
Anti-Migraine: Feverfew works in the treatment and prevention of migraine headaches by inhibiting the release of blood vessel dilating substances from platelets (serotonin and histamine), inhibiting the production of inflammatory substances e.g. leukotrienes, and re-establishing proper blood vessel tone. Associated nausea and vomiting have also been shown to decrease or disappear.
Anti-Inflammatory: Inflammatory compounds released by white blood cells and platelets contribute greatly to the inflammation and cellular damage found in rheumatoid arthritis. The inhibitory effects on inflammatory mediators by feverfew are much greater than NSAIDs such as aspirin.
Feverfew may be of benefit due to its inhibiting effect on the production of pro-inflammatory by-products of arachidonic acid.Prefer high quality extracts providing the broad spectrum of lactones and flavonoids indigenous to this plant.
Anti-Allergy: Parthenolide along with other phytochemicals within feverfew are known to inhibit eicosanoid production such as arachidonic acid and to inhibit histamine release from mast cells.
Anti-Microbial: Compounds found in feverfew have demonstrated antibacterial effects towards staph. Aureus, E. coli, and Salmonella spp. Parthenolide has been shown to inhibit the growth of gram-positive bacteria, yeast, and fungi.
Feverfew (Tanacetum parthenium) This is an herb with a long traditional use, although its most noteworthy application is as a migraine remedy. Its name comes from the latin which meant to drive away a fever, which was its common use in that time. It has an antisecretory action which inhibits platelet aggregation and an antiinflammatory action by inhibiting prostaglandin biosynthesis and arachidonic acid products. So it really is the perfect treatment for migraine and tension headaches, although it is still used for fevers, colds, atonic dyspepsia and worm infestation.
Reference:
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- 1.Feverfew,Dioscorides's Fever Reducer or febrifugia,what is the history of this pretty daisy-like flower?
Article Information:
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