Lighiyellow Sophora Root and Its Extracts!
Article Content:
- .Basic Instruction of Sophora japonica.
- .Plant Description:Basic Phyto Character of Sophora japonica.
- .Chemical Content.
- .Description in brief of Subprostrate Sophora Root.
- .Function and usages of Lighiyellow Sophora Root.
- .Toxicity and Safety.
- .Research Update:Sophora japonica.
Toxicity and Safety.
Safety and Acute toxicity:Matrine
CAS No.:519-02-8.Molecular Formula:C15-H24-N2-O. Molecular Weight:248.41 Synonmys:Matridin-15-one;(+)-Matrine;alpha-Matrine.
Acute toxicity(LD50):Matrine
LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-rat.125 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:CPBTAL Chemical and Pharmaceutical Bulletin.V.6-1958-Volume(issue)/page/year:18,2555,1970.
LD50-Lethal dose,50 percent kill.Intraperitoneal.Rodent-mouse.150 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:CTYAD8 Zhongcaoyao.Chinese Traditional and Herbal Medicine.(China International Book Trading Corp.,POB 2820,Beijing,Peop.Rep.China)V.11-1980-Volume(issue)/page/year:18,214,1987.
LD50-Lethal dose,50 percent kill.Intravenous.Rodent-mouse.64850 ug/kg.
Details of toxic effects not reported other than lethal dose value.
LD50-Lethal dose,50 percent kill.Intramuscular.Rodent-mouse.74150 ug/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:ZYZAEU Zhongguo Yaoxue Zazhi.Chinese Pharmacuetical Journal.(China International Book Trading Corp,.POB 2820,Beijing,Peop.China)V.24-1989-Volume(issue)/page/year:27,201,1992.
Safety and Acute toxicity:Oxymatrine
CAS No.:16837-52-8.Molecular Formula:C15-H24-N2-O2. Molecular Weight:264.41 Synonmys:Matridin-15-one,1-oxide,(1-beta)-;Matrine oxide;Matrine N-oxide;Oxymatrine.
Acute toxicity(LD50):Oxymatrine
LD50-Lethal dose,50 percent kill. Intraperitoneal.Rodent-mouse.521 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:YHTPAD Yaoxue Tongbao.Bulletin of Pharmacology.(China International Book Trading Corp.,POB 2820,Beijing,Peop.Rep.China)V.13-23,1978-88.For publisher information,see ZYZAEU.Volume(issue)/page/year:18(7),23,1983.
LD50-Lethal dose,50 percent kill.Intravenous.Rodent-mouse.150 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:CPBTAL Chemical and Pharmaceutical Bulletin.V.6-1958-Volume(issue)/page/year: 18,2555,1970
LD50-Lethal dose,50 percent kill.Intramuscular.Rodent-mouse.257 mg/kg.
Details of toxic effects not reported other than lethal dose value.
Reference:ZYZAEU Zhongguo Yaoxue Zazhi.Chinese Pharmacuetical Journal.(China International Book Trading Corp,.POB 2820,Beijing,Peop.China)V.24-1989-Volume(issue)/page/year:27,201,1992.
Reference:
1.Lighiyellow Sophora Root and Its Extracts!
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