Aralia elata Root Bark and Its Extracts:Applications and Study!
Article Content:
- .A Brief introduction of Aralia elata.
- .Aralia elata (Miq.) Seem:Classifications and Synonyms.
- .Habit,Form and Physical Characteristics of Aralia Root.
- .Microscopy Aralia Root.
- .Constituents and Phytochemicals.
- .Pharmacological Study.
- .Pharmacopoeia Identifications.
- .Research Update:Aralia elata.
Pharmacological Study.
Total triterpene glycosides from aralia leaf Intravenous injection to cat or rabbit at dose 10mg/kg,make blood pressure drop 20%~25%,continue 15 minutes,such effects not against by atropine,subcutaneous injection 1.25~5mg/kg to mice,lowering narcotism by chloral hydrate and barbital sodium. Total triterpene glycosides 15% lower blood sugar,and lower beta-lipoprotein,but has no effects on level of cholestrol.
1.Cardiovascular Effects:aralia total saponins show good protection against myocardium damage and myocardial infarction. Intraperitoneal injection at dosage 5mg/kg can reduce release of CPK,lowering free fatty acids in muscular tissue of the heart and blood plasma,shows activity of protecting superoxide dismutase.
2.hypoxia tolerance: oral taken aralia total triterpnes to mice brings higher hypoxia tolerance,lowering oxygen metabolic rate,shows protection against histotoxic hypoxia from potassuim cyanide or sodium nitrite,protect against brain hypoxia,total triterpnes boost up partial pressure of oxygen,which proved the triterpen glycosides boost up the oxygen supplying ability to blood and raise up usability of oxygen in tissues.
Medicinal Uses:
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Anodyne; Cancer; Carminative.
The roots and stems are anodyne and carminative. All parts of the plant are used for the treatment of rheumatoid arthralgia, coughs, diabetes, jaundice, stomach ulcers and stomach cancers.
Edible Uses:
Edible Parts: Leaves.Young shoots - cooked. They can also be blanched and used in salads.
Toxicity:oral dose of ethanol saps of aralia root at 2g/kg brings death to most mice,5g/kg oral dose kills rabbit.LD50 of total triterpene for mice by oral dose is 724mg/kg.
Dosage:decoction 15~30g,or dip in alcohol.
Reference:
1.Aralia elata Root Bark and Its Extracts:Applications and Study!
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