Terminalia Belerica and Extract:General Information,Phytochemicals,History,Remedies and Uses Guide.
Article Content:
- .Basic Botanical Info of Terminalia Belerica.
- .Terminalia Belerica General Information.
- .Phytochemicals and Constituents.
- .History of Terminalia Belerica.
- .Modern Medical research.
- .Remedies and Uses Guide.
- .Research Update:Terminalia Belerica.
Phytochemicals and Constituents.
Beta-sitosterol,gallic acid,ellagic acid,ethyl gallate,galloyl glucose,chebulagic acid.
Four lignans including termilignan, thannilignan, hydroxy-3',4'-[methylenedioxy] flavan, and anolignan B identified.
Fruit contains tannins about 23.60%~37.36%,tannins composed of Chebulinic acid(C41 H32 O27)Chebulagicacid(C41 H30 O27);1,3,6-Trigalloylglucose and 1,2,3,4, 6-pentagalloylglucose;Corilagin(C27 H22 O18);Terchebin(C41H30O26);Glucogallin(C13 H16 O10);Ellagic acid and Gallic acid,etc.Other phytochemicals including Shikimic Acid,Dehydro-Shikimic Acid;Quinic acid,arabinose,fructose,sucrose,sugar,Rhamnose and amino acid,triterpenes:terminoic acid;arjugenin;arjunolic acid ;chebupentol.also contains Sennoside A;Chebulin(C28 H48 O4);Tannase;Polyphenol oxidase;peroxidase;ascorbic oxldase,etc.Bark contains beta-sitosterol,tannins,Ellagic acid,Gallic acid and Catechol.
Its principle constituents are beta-sitosterol, gallic acid, ellagic acid, ethyl gallate, galloyl glucose, chebulagic acid. The fruit possesses antibacterial properties. It is employed in dropsy, piles and diarrhea. While using herbal eye drops containing T. bellirica, encouraging results have been obtained in cases of myopia, corneal opacity, pterigium, immature cataract, chronic and acute infective conditions. The fruit possesses myocardial depressive activity
Gallic acid:3,4,5-Trihydroxybenzoic acid:
Formula:C7H6O5
Biological activities of gallic acid include:Analgesic,Antiallergenic,Antibronchitic,Anti-inflammatory,Antioxidant,Antiperoxidant,Antiviral,Bacteristat,Bronchodilator,Immunosuppressant,Astringent
Ellagic acid:
Ellagic acid is a phenolic compound present in fruits and nuts including raspberries, strawberries and walnuts. It is known to inhibit certain carcinogen-induced cancers and may have other chemopreventive properties. The effects of ellagic acid on cell cycle events and apoptosis were studied in cervical carcinoma (CaSki) cells. We found that ellagic acid at a concentration of 10(-5) M induced G arrest within 48 h, inhibited overall cell growth and induced apoptosis in CaSki cells after 72 h of treatment. Activation of the cdk inhibitory protein p21 by ellagic acid suggests a role for ellagic acid in cell cycle regulation of cancer cells.
Ethyl gallate:
CAS NO. 831-61-8
Formula: C6H2(OH)3COOC2H5 ;WT. 198.17
H.S. Code: 2918.29
Synonyms:Gallic acid, ethyl ester; Ethyl 3,4,5-trihydroxybenzoate; 3,4,5-Trihydroxybenzoic acid, ethyl ester;
Other Constituents: ellagic acid;trimethyl ether of gallic acid; trimethyl ethyl of chebulic acid; chebulagic acid; chebulinic acid; chebulic acid; terchubin acid;shikimic acid;dehydroshikimic acid; quinic acid;triacontanoic acid; palmitic acid; beta-sitosterol; daucoterol; 1,3,6-trigallylglucose; 1,2,3,4,6-pentagallylglucose;corilagin; glu-cogallin;sennoside A; tannase; polyphenol oxidase; ascorbic acid oxide;arabinose; fructase; glucose; sucrose; rhamnose;vitamin C; 2alfa-hydroxymicromeric acid; maslinic acid; 2alfa-hydro-xyursolic acid; terminoic acid;arjugenin; arjunolic acid;chebupentol; punicalagin; terflavinA; terchebulin.
Constituents in Volatile Oil: hexadecanoic acid;linoleic acid;9,12-octa-deeadienoic acid;heptadecane;octadecane; cis-alfa-santalol; 2,6-dimethyl hep-tadecane; 2,6-bis(1,1-dimethyl ethyl)-4-methyl phenol; eicosane; benzoic acid; pentadecane.etc.
Reference:
1.Terminalia Belerica and Extract:General Information,Phytochemicals,History,Remedies and Uses Guide.
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