Citrus aurantium and Synephrine.

Citrus aurantium Administration guide and Applications.

Bitter Orange Extract INCI Name Citrus Aurantium Amara Extract CAS 72968-50-4 EINECS ELINCS No 277-143-2 Synephrine Seville Orange Zhi Shi Naranja Agria Neroli Petitgrain Seville Orange Citrus Bergamia Citrus Bigaradia Citrus Vulgaris photo picture image Dosage:How much is usually taken?

Usually 1 to 2 grams of dried peel is simmered for 10 to 15 minutes in a cup of water; three cups are drunk daily. As a tincture, 2 to 3 ml (with a weight-to-volume ratio ranging from 1:1 to 1:5) is often recommended for use three times per day. 10 The purified volatile oil is generally avoided for reasons discussed in the side effects section.

Although historically used to stimulate appetite, bitter orange is frequently found in modern weight-loss formulas because synephrine is similar to the compound ephedrine, which is known to promote weight loss. In one study of 23 overweight adults, participants taking a daily intake of bitter orange (975 mg) combined with caffeine (525 mg) and St. John's wort (Hypericum perforatum, 900 mg) for six weeks lost significantly more body weight and fat than the control group.1 No adverse effects on heart rate or blood pressure were found. Bitter orange standardized to contain 4 to 6% synephrine had an anti-obesity effect in rats. However, the amount used to achieve this effect was accompanied by cardiovascular toxicity and mortality.

Many health professionals recommend 1 to 2 grams of dried bitter orange peel simmered for 10 to 15 minutes in a cup of water. Three cups are usually recommended as a daily dosage. As a tincture, 2 to 3 ml is usually recommended, also to be taken three times a day. Supplementing with pure bitter orange oil is usually avoided.

Are there any side effects or interactions?

Bitter orange oil may possibly cause light sensitivity (photosensitivity), especially in fair-skinned individuals.Generally this occurs only if the oil is applied directly to the skin and then exposed to bright light; in rare cases it has also been known to occur in people who have taken bitter orange internally. The oil should not be applied topically and anyone who uses it internally should avoid bright light, including tanning booths.

Internal use of the volatile oil of bitter orange is also potentially unsafe and should not be undertaken without expert guidance. Large amounts of orange peel have caused intestinal colic, convulsions, and death in children. The amounts recommended above for internal use should not be exceeded.

One text on Chinese medicine cautions against the use of bitter orange in pregnancy.This concern is not raised in any other reference, and the American Herbal Products Association classifies the herb as "class 1," an herb that can be safely consumed during pregnancy when used appropriately.

Decoctions of bitter orange substantially increased blood levels of cyclosporine in pigs, causing toxicity.Bitter orange also inhibited human cytochrome P450 3A (CYP3A) in the test tube.16 This is an enzyme that helps the liver get rid of numerous toxins, and strongly affects metabolism of certain drugs. Bitter orange might, therefore, interact with drugs that are metabolized by CYP3A. To be on the safe side, bitter orange should not be combined with prescription medications, unless someone is under the care of an experienced natural medicine clinician.

At the time of writing, there were no well-known drug interactions with bitter orange.

Applications:

Fruit:

Decoction: Take for indigestion, constipation, or coughs. Combine with dang gui for menstrual pain.
Tincture: Use drop doses for uneasiness, shock, or insomnia.

Neroli Oil:

Cream: Add 1-2 drops to skin cream and apply to any skin condition.
Massage Oil: Add 1-2 drops to 10 ml almond oil for nervous conditions and digestive upsets.

Orange Flower Water: A byproduct of steam distillation: take as a soothing carminative and for uneasiness, shock, or insomnia. Add 5-10 ml to a baby's bottle for colic or sleeplessness.

Peel:

Decoction: Use both types of peel for indigestion and abdominal bloating. Take chen pi for coughs.
Syrup: Take 2-4 ml syrup made from chen pi for coughs.

Orange Caramel Custard With Pineapple Sage:This is an easy yet special dessert. To dissolve caramel that remains in the pot after you empty it, fill the pot with water and bring to a boil.

3/4 cup plus 2 tablespoons sugar
2 tablespoons water
2 large eggs
2 egg yolks
1 1/2 cups milk
2 tablespoons grated orange rind
2 tablespoons minced pineapple sage
1/2 teaspoon vanilla

In a small saucepan, cook the water and 1/2 cup of the sugar over medium heat, stirring until the sugar is dissolved. Use a pastry brush dipped in water to wash down any sugar crystals from the side of the pan. Bring to a boil and cook, swirling the pan rather than stirring, until the sugar becomes a caramel color. Pour the hot caramel into 4 glass custard cups. Tilt the cups to cover the bottom evenly; cool.

Preheat the oven to 325 F degrees. Whisk together the eggs, egg yolks, and remaining sugar. Heat the milk and add it in a stream while whisking the eggs and sugar. Beat in the orange rind, pineapple sage, and vanilla. Fill each cup. Set the cups in a baking pan and fill the pan with enough water to come halfway up the sides of the cups. Bake for 30 minutes or until a knife inserted near the center comes out clean. Cool the cups, then chill for at least 1 hour.

To serve, run a knife around the edge of the cups. Invert a dessert plate over each cup; turn the cup over. The custard and caramel will slide out. Garnish with pineapple sage leaves.

Reference:

1.Citrus aurantium and Synephrine.

last edit date:10th,Mar.2010.

Available Product

Name:Bitter Orange Extract
Serie No:P090
Specifications:Synephrine 5%~98%HPLC.
INCI Name:CITRUS AURANTIUM AMARA EXTRACT
EINECS/ELINCS No.:277-143-2
CAS:72968-50-4
Chem/IUPAC Name:Citrus Aurantium Amara Extract is an extract of the fruit of the bitter orange, Citrus aurantium amara, Rutaceae

Supplying Conditions